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FTL_1473

Victor ID 480
Gene Name FTL_1473
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3952491
NCBI Protein GI 89256762
Locus Tag FTL_1473
Protein Accession YP_514124.1
Taxonomy ID 119857
Gene Starting Position 1396895
Gene Ending Position 1399717
Gene Strand (Orientation) -
Protein Name DNA excision repair enzyme, subunit A
DNA Sequence 
>gi|89255449:1396895-1399717 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
GCTAGAGTAAATCTTTAAGATACTTACCAGTGTATGATTTTTTACAGTTAATTATATCCTCTGGAGTTCC
CTCAAAAATTATCTGCCCTCCTTTACTACCACCTTCTGGACCTAAATCAACAAGCCAATCTGCCATTTTT
ATCACATCTAAATTATGTTCAATAATTACAACAGTATTACCTTTATCACGCAGATCCATGATTACTTTTA
GAAGTTGATGAATATCATAAAAATGTAAACCAGTGGTCGGCTCATCCAATATATATAAGGTTTTACTAGT
TGAACGTTTTGATAGCTCTTTTGCTAATTTAACTCTTTGTGCTTCACCACCAGAAAGAGTAGTAGCACTT
TGTCCTAGCTTAATATACGACAGTCCAACGTTCATCAAAGCTTCCAGCTTAGTCTTAATACTTGGTACTG
CATCATAAAATTCAAGTGCCTCTTCGACAGTCATCTCCAATACTTCGTAAATATTTTTACCTTTGTATTG
CACCGCTAAAGTTTCGCGATTATAACGCTTGCCTTGACAAACATCACAAGCAACATAAACATCTGCGAGA
AAATGCATCTCTACCTTTATAACGCCATCACCTTGACATGCTTCACATCTTCCGCCACGAACATTAAAGC
TAAATCTTCCAGCAATATATCCTCTAGCTCGAGCTTCTGATGTTGCAGCAAATAATTCGCGTATGGGTGT
AAACACTCCCGTATAAGTTGCTGGATTAGAGCGTGGAGTTCTACCTATTGGTGATTGATCAATATCTATA
ACCTTATCAAGGTGATTAAAACCTTTATGTGAGGTATACTGCATTGGTACTAAAATACTTCTGTTTAGTA
AACGAGAAGCCAAAGGATATAAAGTTCTATTTATCAGCGTTGATTTACCTGACCCTGAGACACCTGTCAC
ACATGTCAATGCCCCTAGAGGGATTTTAAGATTATCTCCTTGAAGATTATTACCGACCGCACCACTTATT
TCTAGATAACGATTTTTACTAGCTTTTAGCCTAGTTTTTGGAACTTCAATTTTTCTACGACCACTTAAAT
AATCTGCAGTTAAAGACTTTTTACTCTTGAGTATCGTTTCATAACCGCCAGCAGCAACTACCTCACCACC
ATGTACACCTGCCATTGGTCCCATATCGATTATATAATCTGCTTGACGAATCGCATCCTCATCATGCTCA
ACAACGATTACAGTATTACCTAGATTTTTAAGGTTATGTAAAGCATCAAGCAAACGTTGATTATCCCTTT
GATGAAGACCTATCGATGGCTCATCTAATATATACATCACACCAACAAGACCAGCGCCTATCTGACTTGC
TAAACGAATACGCTGAGCCTCACCACCAGAGAGAGTATCAGCTTGCCTTGCTAAGCTTAAATACTCTAGC
CCAACATTTGCTAAAAACTCTACTCTTAGTTTAATCTCTTTGAGTAAATTCTCTGCGATAACTTGTTGTT
GACCGACAAACTTTAGACTATCCAACCACTTTAATAACTCATCAATAGGCAAAGCACAAACATCAGCTAT
ATTTTTATCAGCAATAAATATATTGCGTGCATATTCATTAATTCTCGCACCATTACAAGACTTACATTCA
AGGTTACTCATAAGCTCATAAAGATCTTTTTTAACCATATCTGAGTCAGACTCATAATATCTGCGTTCAA
AATGAGGTATAACACCCTCAAAAGGTTTAATACGAGTTTGTCTACCTCCTCTGATAGAATCAACACTCAT
TACGATAGCTTCGTCACCAGAACCATATAAGATTATTTCTTGAATTCTTTTAGGTAGCTTCTCAAACCGC
TCATCTAAAGAAAATTTGTAGTGTGTTGCTAAAGACTCTAATTGAGAAAAATAGTATTGATTAGTTTTAT
TCCACTTAACTATAGCTCCATGCTTAAGTGAAATTGATGGATCTATAACAACCTTTTGCTCATCAAAAAA
TTCTTTAACACCAAGTCCATCACAACTGCTACAAGCCCCCAACGGACTGTTAAAAGAAAAAATTCTTGGT
GATAATTCTTTAAGTGCAAAATCACACAAAGGACAAGCATGCTTTGATGAAAATAAGATATCATCGCCAG
TTTGATTTGCCATATCTGCTAATTTAACAATACCATTACCAAGGTCTAAAGCTGTTTCTATTGATTCAGC
GATACGTTGTTCGTTCTCTTTTTTGGGTTTAAATCTATCAATAACGACATCAATATTATGTTTTTTATAA
CGATCCAATTCAGGATAATCTTCATCAAGGTTATAAAACTCGTCATTTATACGCACACGAACATATCCTT
GTGCTAATATCTTATCTAATAAAGTATGATGTGTACCTTTTTTTTGAGAAATAATTGGTGCTAGTATCAT
CAATCTTGAATCTTCATCAAATTCCAAAATTTTATCAACCATTTGGCTGATAGTTTGAGCCTTCAATTCT
ATTTGATGTATCGGACATTTTGGTGTACCAGCTCGTGCAAAAAACACTCGCAGATAATCATATATCTCTG
TTACAGTTCCAACTGTAGATCTTGGATTATGAGATGTTGTTTTTTGATCTATTGAAATAGCTGGAGAAAG
GCCTTCTATATGCTCAATATCTGGTTTATCCATCATCGACAAAAACTGTCTTGCATATGAAGATAATGAC
TCAACATACCTTCTTTGCCCTTCAGCATATAGAGTATCAAAAGCTAATGAAGATTTACCAGAGCCACTTA
ATCCTGTGATAACAGTTAGCTTATCCCGTGGTATCTCAACATCAATATTTTTTAGGTTATGGGTTTTTGC
GCCCTTGACGATAATTTTTTTCA
Protein Sequence 
>gi|89256762|ref|YP_514124.1| DNA excision repair protein subunit A [Francisella tularensis subsp. holarctica LVS] MKKIIVKGAKTHNLKNIDVEIPRDKLTVITGLSGSGKSSLAFDTLYAEGQRRYVESLSSYARQFLSMMDKPDIEHIEGLSPAISIDQKTTSHNPRSTVGTVTEIYDYLRVFFARAGTPKCPIHQIELKAQTISQMVDKILEFDEDSRLMILAPIISQKKGTHHTLLDKILAQGYVRVRINDEFYNLDEDYPELDRYKKHNIDVVIDRFKPKKENEQRIAESIETALDLGNGIVKLADMANQTGDDILFSSKHACPLCDFALKELSPRIFSFNSPLGACSSCDGLGVKEFFDEQKVVIDPSISLKHGAIVKWNKTNQYYFSQLESLATHYKFSLDERFEKLPKRIQEIILYGSGDEAIVMSVDSIRGGRQTRIKPFEGVIPHFERRYYESDSDMVKKDLYELMSNLECKSCNGARINEYARNIFIADKNIADVCALPIDELLKWLDSLKFVGQQQVIAENLLKEIKLRVEFLANVGLEYLSLARQADTLSGGEAQRIRLASQIGAGLVGVMYILDEPSIGLHQRDNQRLLDALHNLKNLGNTVIVVEHDEDAIRQADYIIDMGPMAGVHGGEVVAAGGYETILKSKKSLTADYLSGRRKIEVPKTRLKASKNRYLEISGAVGNNLQGDNLKIPLGALTCVTGVSGSGKSTLINRTLYPLASRLLNRSILVPMQYTSHKGFNHLDKVIDIDQSPIGRTPRSNPATYTGVFTPIRELFAATSEARARGYIAGRFSFNVRGGRCEACQGDGVIKVEMHFLADVYVACDVCQGKRYNRETLAVQYKGKNIYEVLEMTVEEALEFYDAVPSIKTKLEALMNVGLSYIKLGQSATTLSGGEAQRVKLAKELSKRSTSKTLYILDEPTTGLHFYDIHQLLKVIMDLRDKGNTVVIIEHNLDVIKMADWLVDLGPEGGSKGGQIIFEGTPEDIINCKKSYTGKYLKDLL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1473 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0178L, under L: Replication, recombination and repair
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].