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mxiD from Shigella flexneri 5a

Victor ID 48
Gene Name mxiD from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876523
NCBI Protein GI 13449091
Locus Tag pWR501_p152
Protein Accession NP_085307.1
Other Database IDs UniProtKB-ID: MXIE_SHIFL
UniRef100: UniRef100_P0A2S7
UniRef90: UniRef90_P0A2S7
UniRef50: UniRef50_P0A2S7
UniParc: UPI000012FAAE
EMBL: X67206
EMBL: AL391753
EMBL: AF348706
EMBL: AY206439
EMBL: AF386526
EMBL-CDS: CAA47643.1
EMBL-CDS: CAC05819.1
EMBL-CDS: AAK18463.1
EMBL-CDS: AAP79007.1
EMBL-CDS: AAL72330.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093256
EnsemblGenome_TRS: EBESCT00000094212
EnsemblGenome_PRO: EBESCP00000090419
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 116355
Gene Ending Position 116987
Gene Strand (Orientation) +
Protein Name Type III secretion protein
DNA Sequence 
>gi|13448939:116355-116987 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
CATGGAAGGGTTTTTTTTTGTCCGAAATCAAAATATAAAATTCAGTGATAATGTGAACTATCATTATCGC
TTTAACATTAATAGTTGTGCAAAATTTCTTGCTTTTTGGGACTATTTCAGTGGTGCTCTAGTAGAGCATA
GCCATGCTGAAAAATGTATTCATTTCTATCATGAGAATGATCTTCGGGATAGTTGTAATACCGAATCGAT
GCTTGATAAGTTAATGTTAAGATTCATCTTTTCATCTGACCAGAATGTAAGTAATGCACTGGCTATGATA
CGAATGACTGAGTCATATCATTTGGTTCTTTATCTTCTGAGAACTATTGAGAAAGAAAAGGAGGTAAGAA
TAAAGAGTCTGACAGAGCATTATGGTGTGTCGGAGGCTTATTTTAGATCTTTATGTAGAAAAGCTTTAGG
GGCAAAAGTCAAAGAACAACTGAACACTTGGCGGTTAGTAAATGGTTTATTAGATGTATTTTTGCACAAT
CAAACAATCACTTCAGCTGCCATGAATAATGGGTATGCATCAACATCCCATTTTTCAAATGAGATAAAAA
CACGACTAGGCTTTTCTGCAAGAGAATTATCGAATATTACTTTTTTAGTGAAAAAAATAAATGAAAAAAT
TTA
Protein Sequence 
>gi|13449091|ref|NP_085307.1| Type III secretion protein [Shigella flexneri 5a str. M90T] MEGFFFVRNQNIKFSDNVNYHYRFNINSCAKFLAFWDYFSGALVEHSHAEKCIHFYHENDLRDSCNTESMLDKLMLRFIFSSDQNVSNALAMIRMTESYHLVLYLLRTIEKEKEVRIKSLTEHYGVSEAYFRSLCRKALGAKVKEQLNTWRLVNGLLDVFLHNQTITSAAMNNGYASTSHFSNEIKTRLGFSARELSNITFLVKKINEKI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiD mutant is unable to invade HeLa cells or to provoke keratoconjunctivitis in guinea-pigs (Allaoui et al., 1993).
References
Allaoui et al., 1993: Allaoui A, Sansonetti PJ, Parsot C. MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins. Molecular microbiology. 1993; 7(1); 59-68. [PubMed: 8437520].