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phrB

Victor ID 4799
Gene Name phrB
Sequence Strain (Species/Organism) Enterococcus faecalis V583
NCBI Gene ID 1200497
NCBI Protein GI 29376159
Locus Tag EF1598
Genbank Accession AE016830
Protein Accession NP_815313
Taxonomy ID 226185
Gene Starting Position 1550656
Gene Ending Position 1552089
Gene Strand (Orientation) -
Protein Name deoxyribodipyrimidine photolyase
Protein pI 8.17
Protein Weight 55237.86
Protein Length 477
Protein Note similar to GB:M38591, GB:M81457, SP:P08206, PID:179875, PID:180596, GB:X56494, GB:M23725, GB:M26252, SP:P14618, SP:P14786, GB:X56494, GB:M23725, GB:M26252, SP:P14618, and SP:P14786; identified by sequence similarity; putative
DNA Sequence 
>gi|29374661:1550656-1552089 Enterococcus faecalis V583 chromosome, complete genome
TTTATTGAAACCTTGGATTGTTCATTTCTTGATGAATTTCTTTGCTCGCTTCATATAGAAACAATGTTTG
TTTTTTACTTGATGCATAATCGACAATGGGTTTTGGATAATTTTCTCCTAAATGTACATGATATTGCGTT
TGTAAGGCTTCGTTCATTAGATTTGGTTGATGAATATACTTTTGTGGCACTTGCTTAAGTTCTGGAACAT
ATTTTTTGATGAACTGGCCGTCATTATCAAATTTTTTTGACTGGATAATTGGATTAAAAATCCGAAAATA
AGGGACAGCGTCCGTTCCTGTTGAAGCAGCCCATTGCCAGCCACCGATATTATTGGCAGCATCATAGTCA
ATCAACATTTTTTGAAAGTATTTTTCACCCCAACGCCAATCGATGTGTAAATTTTTAACTAAAAAAGAGG
CAGTAATCATTCTTAAGCGATTGTGCATCCAACCAGTTTGATTCAGTTGTCGCATTGCGGCATCAATTAT
AGGGTACCCCGTCTCCCCTTTTTGCCACTTGACAAACATTTCTGGGTCATTTGTCCATTGAATATAACGA
AATTTTTCTTGAATAGCTTCCTCTTTTTGTTGTGGAAACGCACTATAGATCATATTGTAAAAGTCGCGCC
AAGCTAATTCTTTTTTGAAGGTTTCTTTACTTAAGCTAGAAGGCACAGATGCAAGCTCTTGCCAAATGGT
GCGAATCGAAAGTTCTCCCGTTCTTAAAAAAGTAGACAGATGACTCGTTTGATCCTGATAAGGAAAATCA
CGCTTATTTTCATAGGATTGAAGTTTTTGATCAATAAAAGTATTTAAGCGCCTTCTGGCTGTTTCTTCGC
CGACACTATAGTGTGTTAAAGGAATCCTCGCAATCTGTTCACGATAAGCTGCTTCCTCTTCTGGAAAAAG
ACACGCACTAAAAATTTTTTCAGCTGTATAGGAAACAGGAATCGGTGTTTCTTTAGGCGCCTCTTTCCAT
TTATTGTAATAGGGCGTAAACACTTGGTACTTGCTGCCATCGTTCTTCTTAATTTCTTCAGAGCCATGCA
AATAGGCATCTTGAAAAGAGAAAGACTGAATATTATTTTCTTCAAAAAAGCGCATAGCTTGCTGGTCCCG
CTTTGCCCCAAAGCCACAAGTATCTTCATTAAAATAAATGGCCTGCCAATCGGGTAATTTGCGTTTCAAA
CGTGAAAATAAATCTAATGGTTCGCCGACCATGATTTGTAAATGTGCCTCTTGATCGATTCGTTCTTTGA
ACGAGGCTAAGCTTGCAAAAAAAGCGTTATGATTAGCACTTTCTTGAATAAATTGTTGAGGATTCATTTG
GAATAATAAAATCAATTCATCAGCTGCAGAATTTTGTAACGCGTGTGCTAATGCTTTATTATCCTGTAAT
CGTAAATCACGTCTAAACCATATTACTCTTTTCA
Protein Sequence 
>gi|29376159|ref|NP_815313.1| deoxyribodipyrimidine photolyase [Enterococcus faecalis V583]
MKRVIWFRRDLRLQDNKALAHALQNSAADELILLFQMNPQQFIQESANHNAFFASLASFKERIDQEAHLQ
IMVGEPLDLFSRLKRKLPDWQAIYFNEDTCGFGAKRDQQAMRFFEENNIQSFSFQDAYLHGSEEIKKNDG
SKYQVFTPYYNKWKEAPKETPIPVSYTAEKIFSACLFPEEEAAYREQIARIPLTHYSVGEETARRRLNTF
IDQKLQSYENKRDFPYQDQTSHLSTFLRTGELSIRTIWQELASVPSSLSKETFKKELAWRDFYNMIYSAF
PQQKEEAIQEKFRYIQWTNDPEMFVKWQKGETGYPIIDAAMRQLNQTGWMHNRLRMITASFLVKNLHIDW
RWGEKYFQKMLIDYDAANNIGGWQWAASTGTDAVPYFRIFNPIIQSKKFDNDGQFIKKYVPELKQVPQKY
IHQPNLMNEALQTQYHVHLGENYPKPIVDYASSKKQTLFLYEASKEIHQEMNNPRFQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: phrB mutant is attenuated in killing C. elegans and is attenuated in mice (Maadani et al., 2007).
References
Maadani et al., 2007: Maadani A, Fox KA, Mylonakis E, Garsin DA. Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host. Infection and immunity. 2007; 75(5); 2634-2637. [PubMed: 17307944].