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efaA

Victor ID 4783
Gene Name efaA
Sequence Strain (Species/Organism) Enterococcus faecalis
NCBI Protein GI 306753329
Other Database IDs CDD:185870
CDD:29734
Taxonomy ID 1351
Gene Strand (Orientation) ?
Protein Name endocarditis specific antigen
Protein Length 230
Protein Note Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface...; cl00262
Protein Sequence 
>gi|306753329|gb|ADN04037.1| endocarditis specific antigen [Enterococcus faecalis]
AAEKKEKLAIVTTNSILSDLVKNVGQDKIELHSIVPIGTDPHEYEPLPEDIAKASEADILFFNGLNLETG
GDGWFNKLMKTAKKVENKDYFSTSKNVTPQYLTSAGQEQTEDPHAWLDIENGIKYVENIRDVLVEKDPKN
KDFYTENAKNYTEKLSKLHEEAKAKFADIPDDKKLLVTSEGAFKYFSKAYDLNAAYIWEINTESQGTPEQ
MTTIIDTIKKSKAPVLFVET
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: efaA mutant is attenuated in mouse peritonitis model (Singh et al., 1998b).
References
Singh et al., 1998: Singh KV, Coque TM, Weinstock GM, Murray BE. In vivo testing of an Enterococcus faecalis efaA mutant and use of efaA homologs for species identification. FEMS immunology and medical microbiology. 1998; 21(4); 323-331. [PubMed: 9753005].