Victors

EF3314
Victor ID	4772
Gene Name	EF3314
Sequence Strain (Species/Organism)	Enterococcus faecalis V583
NCBI Gene ID	1202157
NCBI Protein GI	29377755
Locus Tag	EF3314
Genbank Accession	AE016830
Protein Accession	NP_816909
Taxonomy ID	226185
Gene Starting Position	3195823
Gene Ending Position	3201057
Gene Strand (Orientation)	-
Protein Name	cell wall surface anchor family protein
Protein pI	4.05
Protein Weight	157822.65
Protein Length	1744
Protein Note	similar to GP:7741985; identified by sequence similarity; putative
DNA Sequence	>gi\|29374661:3195823-3201057 Enterococcus faecalis V583 chromosome, complete genome GCTAGTTTTTACGTTTGCGTTTGATGATTCCCATGCTCGCAAGGAGTGCGACAAAGGCGCCAAACAAACT TGTTGTCACGGCTGAAGACTCTTTTTCACCTGTGCTAGGTAAGTAGCCTGTTTTCCCGTGATTTCCAGTG CCATAACTGATGGTACTTAGTTTAGGGTGGTAGCCACTACCATTTGTACCGAGGCCATTGCCTAGTGAAC CTAAGCCAGAACCTGTTGTGCCTAAACCAGAACCTCCATTTGGATTTGAACCTGTGTTTGAACCATTCCC ATTATTCCCGCCAGTTGCGCCATTGTTTCCTGTATTGCCGCCTGTATTGCCGTTATTTCCGCCAGTGTTA CCATTGCCTCCTCCAGGATTCGTTGGGTCGGCTGGCGTCATGAAGGTTGTAGCCGTACTGTAATGTCCTG CGCCATCGGTAGCTGTCGCAAGTAAACTTTGTTGAGCAGTCGCTTGTCCCGCTGTTAATTGGATAGCGAA GTTGCCTTCAGCATCGGTGGCACCTACAGCAATCACACTTCTTAATAGTCGGTTACTAATTTGAATGATT CGGTTTGGTTCAGCTGTTCCTTTGATGAGGTAGCCGGCTTTAGACGTTCCTAAAACTGAAGAAACAGTTG GTGCCGCAATTTTAATCTCTGGTTCTCCCGTAATATCGGCTGGCGTCATAAATGTGGTTTTAGGACTCAC ATTTCCTTGTGTATCTGTGGTTAGTGCGGTTAACGTTTCTTTTTCTGTTGCTAACCCTGCTGCAATATGA ACGGAGAAGGTACCTCCAGTAGTTGTATTGCCACTTGCCAATAATTGTTCACTGCTATTGTAAAATTGAA CCGTGACATTTGGATCAGCAGTTCCAGTGACTGTATAGCCATTGGCTTTGTTTCCTTCAACCTTCGTAAT AGTTGGCGCCGCTAAAACAACATCCGCTGGAATAACGGCTGTAGCTGGTTGACTTTCATTACCTGCGCCA TCTTTGCTAATAATCGTAATCGTTTCTCCTGGTGTCACTACGCCAGCTGGTAGAGTCACCGTATATTGGC CGGTTTCGTTAGCAGTTGTAGCAGCAATGATGGTTCCGTCTGCGTCACGGACATCAATAGTGGTTTTTGG CTCCGCCGTTCCAGTGATTTCGTAACCTTTACTAGAATTTCCGGTAATAGAATCAATGGTTGGTGTGGCT AAGTCGACTGGTGTAGTTGCTGTAGCTGGCTGACTTTCTTTTCCTGTTGCATTTTTCGCTACGACAGTTA TTGTTTCGTTAGCTGAGGCCTTCCCTGGCTCTAAAGTCACTGTGTATTTGCCATCAGTTCCAGTAGTTGC CATGCCAAGGACTGTGCCATCGGCGTCACGCACCTCAACTGTTGTACCAACTTCTGCTGCTCCTACTACT TGATAGCCGTTTGTCGTGCTACCAGTGATTTTGTCAACAGTAGGTGTCGCGACTGGTGCATCTGGATCAG CAGGTGTTTTGAAAGCAGTCGGATTACTTTCTTTCCCAGCAGCATCTTTCGCAATGGCAGTTAAGGCTTC GTTAGCTGTTGCTGTGCCCGTCGGAAGAGTGATTGTAAATGCGCCAGCACCATCAGTCGTTCCCGTAGCA ATAACTAAACCTGCTTCATTGTGAATCTCAATGGTGACATTTGGCTCTGCCGTGCCGGTTACTTGATACC CAGTGGCAGTTGTTCCTGTAACAGTCGTCACAGTTGGTGCTGCTACGGTTGCATCTTCAGGGACCGTCAC TTCCGTTGGTTGACTTTCATTGCCGTCACCGTCTTTTCCAACAACTGTTAATGTATCACCAGGATTAGCG GCTCCCGCTGGAAGGTCCACAGTAAAGTTTCCTTGATCATCCGTTGTCGTTGTACCAATAATTGTTCCAT CTGGGTTCCGTACTTCAATGGTGGTATTAGGGTCCGCCGTCCCAGTGATTTCATAACCAGTTGTTGAATC TCCAGTAATGTCACCAATTGTTGGTGTGGTAACATCAGCGGGTGTCATAGCTGTAGTTGGTTGACTCTCA AGTCCAGTATCATTTTTAGCAACTACATTCACTGTTTGTTTAGCTGTTGCTTTTCCTGAAGCTAACGTCA CAGTATATTGGCCAGTCGGTCCAGTTGTTGCGGTGCCTAAAACTGTTCCGTCTGTTGCACGAACTTCAAT GGTGGTGCCAAGTTCAGCGGTACCTGTCACTTGATATCCTTGTGTTGTATTCCCAGTAACTTTGTCGACA CTTGGCGGTGCCACTACTTCATCTGCTGGTGTTTGGAAGGTTGTCGGTGTACTTGTATTGCCAGCAGGAT CTTTGGCTAACGCTGTCAATGTTTCATTCGCATTTGCCGTCCCAGCTGGAAGGTTCACAGCAAAGGAACC AGTCCCATCGGCAGTCCCTGTTGCAATCACGTTCCCATCTGCATCACGAATTTCGATGGTAGCATTCGGA TCAGCGGTGCCTGTCACCTGATAACCAGCAACTGAATTACCTGTTACTCCTGTTACAGTTGGTGCTGTAA CCGTGGCATCAGCAGGAACAAGGACTTCAGTCGGTTGACTTTCATTTCCCGCGTTATCCTTTCCAATCAC TGTTAACGTATCCCCAGGATTGGTCGTTCCCGTTGGTAGCGTTACAGTAAAATCACCATTCGCATCAGAG GTACCTGTACCAATGACTGCCCCAGATGGATCACGAACTTCGATTGTTGTGTTAGGGTCTGCTGTTCCTG TAATTTCATAACCCGAACCAGAGTTGCCTGTGATGTTATCAACTGTTGGTGCAGTGACATCAGCTGGTGT TGTCGCCGTTGCTGGTTGACTTTCCGTGCCACTAGCGTTTTTCGCTACAACGCTCAGCGTTTGATTTGCT GTTGCTGTTCCTGAATCTAAAGTCACTGTATATTTTCCGTCAGTTCCAGTTGTTGCAGTACCAAGGACCG TGCCAGCTGCATCGCGAACCTCAATGGTGGTGCCAACTTCAGCAGTCCCTTTGACCTCATAGCCTTTTGT TGTACTACCTGTTACAGTCTCAACAATTGGCGTCGCCACGGGCGTATTAGGATCCGCTGGCGTTTGGAAC GTTGTTGGCGTACTTTCTGTACCGCTGGCGTTTTTCGCTACGGCGGTTAACGTTTCATTCGCACCTGCTT CACCTGCGGGAATGGTAACTGTAAATGCCCCTGTCCCATCAGCAGTACCTGTACCTATCACGGCACCTCC TGCATTTCGGATCTCAACCGTGGCATTGGCATCGGCAGTTCCTTTAACTTCGTAACCTGCTGTTGAATTA CCTGTCACTCCTGTGATTGTTGGTGCGGTTACGGTTGCTTCATCCGCTGGTGTTTGGAACGTTGTTGGCG TACTTTCTGTGCCGCTGGCGTTTTTCGCTACGGCGGTTAACGTTTCATTGGCACCTGCTTCACCTGCGGG AACGGTAACTGTAAACGCTCCTGTCCCATCAGCGGTACCTGTGCCTATTACGGTGCCTCCTGCATTTCGG ATTTCAACCGTGGCATTGGCATCGGCAGTTCCTTTAACTTCGTAACCTGCCGTTGAATTACCTGTCACTC CTGTGATTGTTGGTGCGGTTACGGTTGCTTCATCCGCTGGTGTTTGGAACGTTGTTGGCGTACTTTCTGT ACCGCTGGCGTTTTTCGCTACGGCGGTTAACGTTTCATTGGCGCCTGCTTCACCTGCGGGAACGGTAACT GTAAACGCTCCTGTCCCATCAGCGGTACCTGTGCCTATTACGGTGCCTCCTGCATTTCGGATTTCAACTG TGGCATTGGCATCAGCAGTTCCTTTAACCTCGTAACCTGCCGTTGAATTACCTGTCACTCCTGTGATTGT TGGTGCGGTTACGGTTGCTTCATCCGCTGGCGTTTGGAACGTTGTTGGCGTGCTTTCTGTGCCGCTGGCG TTTTTCGCTACGGCGGTTAACGTTTCATTGGCGCCTGCTTCACCTGCGGGAACGGTAACTGTAAACGCTC CTGTCCCATCAGCGGTACCTGTGCCTATTACGGTGCCTCCTGCATTTCGGATTTCAACCGTGGCATTGGC ATCGGCAGTTCCTTTAACTTCGTAACCTGCTGTTGAATTACCTGTTACTCCTGTGATTGTTGGTGCGGTT ACTTCACTAGTAGTGCCTGCAGCAAAATAAATGTTGGATACACCGTCTGCTGTTGCTAATAAATTAACGT CTAAAAGATCTGTTTGAACGACTGTTCCTACAAAACGAGCATCTAAATTATTGGATAAATTTTGAGGTGT TGAAACGGTAGTTGGTAAAGTAACCGTGGTTGTGCCTAGTAAAGAAGCATCCACTAACTCATTTACGCCT GAACCACCAACCGCTAATAAAGGCAAAGCACCTGAAACAGCCACGTTTACCGTGCCTTTGACAGGAAGCA AGGCTGCATTTATAGCTGCGGCGACAAGATTACTTGGGATACTGGTACCTTTTGCCTCCAAAGCTTGAAC TGCCGCATTCAAATCTTGTAAGATGTTTGAAACATTTTGGGCTAAAACTAACCCTAAACCATCACTAATC GGTGCACTAATGTATGAGCCGTCAGCTGCTAACGTTTCCGGAGCTGTAAATGAAGCAGCACCTAAGTTTT CAATGTTATTAACTAATTCCAATTGACGATTCACTTCCGTCAAATCAATATCAACACCAGTTAAATTCCC TAACGCCCCACTGGTAATTTGAGTAATCACATTGGTTAAATCATTGGCTGCATTCAAAACGGCAGTCAAA AAAGTAACTTTTGAAAGATCAATCGTGACATTGGTATTGATTGCTGCGCTGCCTGCTGCAGCTACATTTC CTCTTAACTCAGGAGGAACCACTAACACCGCTTGTTTTTGTCCACTAAACACAGCGGAAGCATCTGCTAA AGCGCCACCAGAAACCGTGAAATTAACTGGTTGATTTTGGTTTGCGGCTGTCCAACGATTACTCGTTGAA GTGCCACTGTCATTATTTGACGTAACATTTGATAATAGTTCGATATCCAAGACCGCTGCTGATGCACTGA TTGTGCCAGAGGTAACAGCTATACTTACAGGGATTGCTAATGACGTAAATAATAAACCACTTGATATTGC TAAATTAAGCATCTTGCGTTTTGTCCATTTTTTATGCTGACTTTTCCGATTAAAATCCTCAACAATTTTC TTTTTCATCTGATCGTCCCTCTTTTCTTTAAAATAAACGATAAATACCAAGATCA
Protein Sequence	>gi\|29377755\|ref\|NP_816909.1\| cell wall surface anchor family protein [Enterococcus faecalis V583] MILVFIVYFKEKRDDQMKKKIVEDFNRKSQHKKWTKRKMLNLAISSGLLFTSLAIPVSIAVTSGTISASA AVLDIELLSNVTSNNDSGTSTSNRWTAANQNQPVNFTVSGGALADASAVFSGQKQAVLVVPPELRGNVAA AGSAAINTNVTIDLSKVTFLTAVLNAANDLTNVITQITSGALGNLTGVDIDLTEVNRQLELVNNIENLGA ASFTAPETLAADGSYISAPISDGLGLVLAQNVSNILQDLNAAVQALEAKGTSIPSNLVAAAINAALLPVK GTVNVAVSGALPLLAVGGSGVNELVDASLLGTTTVTLPTTVSTPQNLSNNLDARFVGTVVQTDLLDVNLL ATADGVSNIYFAAGTTSEVTAPTITGVTGNSTAGYEVKGTADANATVEIRNAGGTVIGTGTADGTGAFTV TVPAGEAGANETLTAVAKNASGTESTPTTFQTPADEATVTAPTITGVTGNSTAGYEVKGTADANATVEIR NAGGTVIGTGTADGTGAFTVTVPAGEAGANETLTAVAKNASGTESTPTTFQTPADEATVTAPTITGVTGN STAGYEVKGTADANATVEIRNAGGTVIGTGTADGTGAFTVTVPAGEAGANETLTAVAKNASGTESTPTTF QTPADEATVTAPTITGVTGNSTAGYEVKGTADANATVEIRNAGGAVIGTGTADGTGAFTVTIPAGEAGAN ETLTAVAKNASGTESTPTTFQTPADPNTPVATPIVETVTGSTTKGYEVKGTAEVGTTIEVRDAAGTVLGT ATTGTDGKYTVTLDSGTATANQTLSVVAKNASGTESQPATATTPADVTAPTVDNITGNSGSGYEITGTAD PNTTIEVRDPSGAVIGTGTSDANGDFTVTLPTGTTNPGDTLTVIGKDNAGNESQPTEVLVPADATVTAPT VTGVTGNSVAGYQVTGTADPNATIEIRDADGNVIATGTADGTGSFAVNLPAGTANANETLTALAKDPAGN TSTPTTFQTPADEVVAPPSVDKVTGNTTQGYQVTGTAELGTTIEVRATDGTVLGTATTGPTGQYTVTLAS GKATAKQTVNVVAKNDTGLESQPTTAMTPADVTTPTIGDITGDSTTGYEITGTADPNTTIEVRNPDGTII GTTTTDDQGNFTVDLPAGAANPGDTLTVVGKDGDGNESQPTEVTVPEDATVAAPTVTTVTGTTATGYQVT GTAEPNVTIEIHNEAGLVIATGTTDGAGAFTITLPTGTATANEALTAIAKDAAGKESNPTAFKTPADPDA PVATPTVDKITGSTTNGYQVVGAAEVGTTVEVRDADGTVLGMATTGTDGKYTVTLEPGKASANETITVVA KNATGKESQPATATTPVDLATPTIDSITGNSSKGYEITGTAEPKTTIDVRDADGTIIAATTANETGQYTV TLPAGVVTPGETITIISKDGAGNESQPATAVIPADVVLAAPTITKVEGNKANGYTVTGTADPNVTVQFYN SSEQLLASGNTTTGGTFSVHIAAGLATEKETLTALTTDTQGNVSPKTTFMTPADITGEPEIKIAAPTVSS VLGTSKAGYLIKGTAEPNRIIQISNRLLRSVIAVGATDAEGNFAIQLTAGQATAQQSLLATATDGAGHYS TATTFMTPADPTNPGGGNGNTGGNNGNTGGNTGNNGATGGNNGNGSNTGSNPNGGSGLGTTGSGLGSLGN GLGTNGSGYHPKLSTISYGTGNHGKTGYLPSTGEKESSAVTTSLFGAFVALLASMGIIKRKRKN
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: EF3314 deletion mutant is attenuated in attachment to HeLa cells, survival within macrophages and in a C. elegans killing model (Creti et al., 2009).
References	*Creti et al., 2009:* Creti R, Fabretti F, Koch S, Huebner J, Garsin DA, Baldassarri L, Montanaro L, Arciola CR. Surface protein EF3314 contributes to virulence properties of Enterococcus faecalis. The International journal of artificial organs. 2009; 32(9); 611-620. [PubMed: 19856273].


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EF3314