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ace

Victor ID 4771
Gene Name ace
Sequence Strain (Species/Organism) Enterococcus faecalis OG1RF
NCBI Nucleotide GI 10863204
NCBI Protein GI 10863205
Protein Accession AAG23931.1
Taxonomy ID 474186
Gene Strand (Orientation) ?
Protein Name collagen adhesin precursor
Protein Note Region: A domain
DNA Sequence 
>gi|10863204|gb|AF260872.1| Enterococcus faecalis strain OG1RF collagen adhesin precursor (ace) gene, complete cds
ACCACTAAGTGGAAAAAATAAGAGAAAAGAAGGGTGAATAATTTTTTATGACAAAAAGTGTAAAATTTTT
AGTGTTACTGTTGGTAATGATTCTACCAATTGCGGGGGCGTTATTGATTGGTCCAATTTCGTTTGGCGCC
GAATTGAGCAAAAGTTCAATCGTTGACAAAGTAGAATTAGATCACACTACTTTATATCAAGGAGAGATGA
CCTCAATTAAAGTATCTTTTAGTGACAAAGAAAATCAGAAAATAAAACCTGGAGATACTATTACTTTAAC
TTTACCAGACGCACTAGTTGGAATGACCGAGAACGATGGTTCACCACGAAAAATCAATTTAAATGGTTTA
GGGGAAGTTTTTATCTATAAAGATCATGTTGTAGCAACATTTAACGAAAAAGTTGAATCTTTACATAATG
TGAATGGGCATTTTTCTTTCGGGATTAAAACGCTTATCACCAATAGTTCGCAACCGAACGTGATAGAAAC
GGATTTCGGAACAGCAACGGCGACTCAACGTTTGACGATTGAAGGAGTGACTAACACAGAGACTGGCCAA
ATTGAGCGAGACTATCCGTTTTTTTATAAAGTAGGCGATTTGGCTGGAGAGTCAAATCAAGTACGTTGGT
TTTTAAATGTGAACCTCAATAAATCCGATGTCACAGAAGATATTTCAATTGCGGATCGACAAGGAAGTGG
TCAACAATTAAATAAAGAGAGTTTTACATTTGATATTGTGAATGACAAAGAAACTAAATATATTTCACTT
GCCGAGTTTGAGCAACAAGGTTATGGCAAAATTGACTTCGTGACAGATAATGACTTTAATTTACGTTTTT
ATCGGAATAAAGCACGCTTTACTTCCTTTATCGTCCGTTACACTTCGACAATCACAGAAGCAGGCCAACA
TCAAGCAACATTTGAAAATAGTTATGACATCAATTATCAACTAAACAATCAAGACGCAACGAATGAAAAA
AATACATCACAGGTTAAAAATGTTTTTGTAGAAGGCGAGGCAAGCGGCAATCAAAATGTGGAAATGCCAA
CAGAAGAAAGTCTAGACATTCCTTTAGAGACAATAGATGAATGGGAACCAAAGACACCTACTTCGGAACA
GGCAACAGAAACAAGTGAAAAGACAGGCGCAACAGAAACTGCAGAAAGCAGCCAACCAGAAGTTCATGTC
TCGCCAACAGAAGAAGAAAATCCAGATGAAGGTGGAACACTAGGCACGATTGAGCCAATCATACCTGAAA
AACCAAGTGTGACAACTGAAGAGAATGGCGTAACAGAAACTGCAGAAGGCAGCCAACCAGAAGTTCATGT
CTCTCCAACAGAAGAAGAAAATCCAGATGAAAGTGAAACGTTAGGTACAATTACACCAATTATTCCTGAA
AAACCAAGTGTGACAACTGAAGAGAATGGCGTAACAGAAACTGCAGAAGGCAGCCAACCAGAAGTTCATG
TCTCTCCAACAGAAGAAGAAAATCCAGATGAAAGTGAAACGTTAGGTACAATTACACCAATTATTCCTGA
AAAACCAAGCGTAACAACTGAAGAGAACGGCGCAACAGAAACTGCAGAAAGCAGCCAACCAGAAGTTCAT
GTCTCACCAGCGGAAGAAGAAAATCCAGATGAAAGTGAAACGTTAGGTACAATTACACCAATTATTCCTG
AAAAACCAAGTGTGACAACTGAAGAGAACGGCACAACAGAAACCGCAGAAAGCAGTCAACCAGAAGTTCA
TGTCTCACCAACAGAAGAAGAAAATCTAGATGAAAGTGAAACACTAGGCACGATTGAGCCAATCATACCT
GAAAAACCAAGCGTAACAACTGAAGAGAATGGCACAACGGAAACGGCAGAAAGCAGCCAACCAGAAGTTC
ATGTGTCGCCAACAAAAGAAATTACTACAACTGAGAAAAAACAGCCATCCACAGAAACAACTGTGGAGAA
AAATAAAAATGTTACATCAAAAAATCAACCACAAATACTAAACGCTCCATTAAATACAGTGAAAAATGAA
GGAAGCCCACAGTTGGCTCCCCAACTGCTTAGTGAACCAATTCAAAAATTAAATGAAGCAAACGGGCAAC
GAGAACTTCCCAAAACAGGCACAACAAAAACACCGTTTATGCTAATAGCAGGAATACTGGCAAGTACATT
TGCCGTTTTAGGTGTAAGTTATCTACAAATCAGAAAGAATTAACAATAGAAAAGCCATCCAGCTTTCGCT
GGGGG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: an ace deletion mutant is significantly attenuated in a mixed infection rat endocarditis model (Singh et al., 2010).
References
Singh et al., 2010: Singh KV, Nallapareddy SR, Sillanpää J, Murray BE. Importance of the collagen adhesin ace in pathogenesis and protection against Enterococcus faecalis experimental endocarditis. PLoS pathogens. 2010; 6(1); e1000716. [PubMed: 20072611].