Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

TSA1

Victor ID 4768
Gene Name TSA1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Protein GI 32140413
Other Database IDs CDD:30799
CDD:48564
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name thiol-specific antioxidant protein 1
Protein Length 197
Protein Note Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; COG0450
Protein Sequence 
>gi|32140413|gb|AAP68994.1| thiol-specific antioxidant protein 1 [Cryptococcus neoformans var. grubii]
MATYALPQIQKPAPNFAGTAVKEGSFEEIKLDDFKGKWTVLVFYPMDFTFVCPTEILAFNKALDQFAAIG
AEVICVSTDSEFTHLAWSQTKRSEGGLGPDLKLTLLADRNHAAAKAYGVLLPEEGVALRGTFFIDPKGTL
RAMHVHDLPVGRSVEETIRVIKAFQFTDEHGEVCPAGWEEGKDTIDTSAPSAYFSKQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: TSA1 mutant is attenuated in mice (Missall et al., 2004).
References
Missall et al., 2004: Missall TA, Pusateri ME, Lodge JK. Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. Molecular microbiology. 2004; 51(5); 1447-1458. [PubMed: 14982637].