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STE20alpha

Victor ID 4765
Gene Name STE20alpha
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Protein GI 25573205
Other Database IDs CDD:176418
CDD:29038
CDD:173728
CDD:128516
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name STE20
Protein Length 644
Protein Note mating type alpha
Protein Sequence 
>gi|25573205|gb|AAN75173.1| STE20 [Cryptococcus neoformans var. grubii]
MAFSPSLTPSRPAPVPPRRAAITAPYIVRVTDASAAPQSNFSATSYSPSFSYTNSSIPSTKVLDTTRSRT
IRSGAASIKEEGLRAFMWSKRWLVLGSAELRIYKNESSPSPVYTVSLEDIQDVQRVDMKPYCVEIETSDK
LLYLAFRSDNEVYGWMDDIYSRSPRLGVSQPTNFVHQVHVGFDPKSGGFTGLPPQWSKLLTSSAITKEEA
ARNPEAVLDVLQFYTQQQAGNVLEGYQQFPMPTVSNQSLTTGAAATRFEGVGLGGQQHQQQQQLRSAPFT
APGSLEAITVVPARPSFETEEKTSAQKEKEKVLNPQHQLLESTRPAMAKFDKEKVTRSPGPTMEKRISTM
NEVQIMEKLRSVVSAKDPSQLYSKIRKVGQGASGMVFVAKTLLNGKKVAVKQMDLSQQPRKELIVNEIIV
MRESQHPNVVNFLDAFLVRGSELWVVMEYMEGGALTDVIENNKLEENQIAAICLETCRGLQHLHSRSIIH
RDIKSDNLLMNTQGEVKITDFGFCAKLTDQKSKRATMVGTPYWMAPEVVKQKEYGAKVDIWSLGIMTIEM
IENEPPYLDEEPLKALYLIATNGTPTLKSPEKLSQDLKHFLSVCLCVDVAFRATSTELLKHEFLQLACSV
RDLAPLLRFKQDTL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ste20alpha mutant is attenuated in mice (Wang et al., 2002).
References
Wang et al., 2002: Wang P, Nichols CB, Lengeler KB, Cardenas ME, Cox GM, Perfect JR, Heitman J. Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. Eukaryotic cell. 2002; 1(2); 257-272. [PubMed: 12455960].