Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

STE12a

Victor ID 4764
Gene Name STE12a
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans
NCBI Protein GI 12247088
Other Database IDs CDD:155007
CDD:143876
Taxonomy ID 40410
Gene Strand (Orientation) ?
Protein Name STE12a
Protein Length 606
Protein Note contains homeodomain and C2H2 zinc fingers
Protein Sequence 
>gi|12247088|gb|AAG49739.1|AF242352_1 STE12a [Cryptococcus neoformans var. neoformans]
MSNTTPDCQTARSKDIAQTDTRNECPRNLEVVRRHPESPFLPEDLYILPVPIYRSPRLPNEEEMKRIKIL
ERLQFFLTTAPTQWSGEISKTEASMVKFPLPRGEQVSCVLWNGLFHITGTDIVRALSFRFDAFSRPIKRS
RKWEEGVFSDLRNLKAGVDATLEEPKSPLLDYLFRNGCIRTQKKQKVFYWFSVPHDRLFLDALERDLKRE
KAGREPTSVIQGEPARSFRYDPRKALYEQFGSETEKVASTVNNVSRLIDPGQPHYDVPIILDECSDARSH
HFAPPFKGRNHMLLACNKSISQASRHLVGTADEPSECGVRSKGSESSYLRPTYFNTAPDPTLPTDSYLNS
STHLLATAARVHIPSLGSPDDREKCSSLLPSPTHERPQNNVRVFNCPYDFCKRPFKRFEHLRRHVRCHTD
DRPFTCDICHRTFTRRDNLAQHAKTHNKSRNHTEMQHQCQFQPNRSISIPVGHDLFTTGRGLGERIEGNV
AIETKSPALSRAITAPPVWVGAIPPLPTEDSPIPPILTTGPSSTFFPMPTTHSLPLLGSHVPHLRSIAED
RNSSFILGPCKSPVLLHPLISLHDDKETLQKHAANMSWPINDTDVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: STE12a deletion mutant is attenuated in mice (Chang et al., 2001).
References
Chang et al., 2001: Chang YC, Penoyer LA, Kwon-Chung KJ. The second STE12 homologue of Cryptococcus neoformans is MATa-specific and plays an important role in virulence. Proceedings of the National Academy of Sciences of the United States of America. 2001; 98(6); 3258-3263. [PubMed: 11248066].