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SCH9

Victor ID 4761
Gene Name SCH9
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Protein GI 20385903
Other Database IDs CDD:176438
CDD:173677
CDD:128516
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name protein kinase Sch9
Protein Length 690
Protein Note C2 domain; cl14603
Protein Sequence 
>gi|20385903|gb|AAM21494.1|AF430213_1 protein kinase Sch9 [Cryptococcus neoformans var. grubii]
MRKAMANDGQGTTESTEAAMENSQTNLSHTSRTTGPKGTLRVKVISARGLAVSHSPGAEPQPYVVIQFEQ
NEYVSRPPHPVTSASSVPFTTSTPQPIGTPNNLTRSSSGLGVGAISRAFADAVGRGKKKEDGSGTMTPKA
EEPAGGSWLGKPGPGDPVWKEEVSFDVTSSKPTLHLSVYDRNRDGEGFLGMLDIKPVLQDGYVLDNWYKL
DTRGDETVTGEVWIQMTYTIIRKRISLKPSDFEFLKLIGRGTFGRVFQVRKKDTRRIYAMKVLSKKEIVA
KKEVAHTIGERKILQCSLECPFLVGLKFSFQTDTELYFVTDYKCGGELFWHLQKEGRFQRRSGGLQKEGR
FSEDRARFYIAELVLALEHLHKYNIVYRDLKPENILLDATGHVALCDFGLSKPDLTDDKLTNTFCGTTEY
LAPEVLLDEKGYGKHVDFWSLGVLLFEMCCGWSPFYAEQTQEMYRLICYGKIRFPKNVIGDDGKQFVKGL
LNRNPQNRLGSHRGAVELKEHPFFKNIDWDLLYKKQITPPFKPIVDSDESVANFDPEFTNSSLLDAGIVP
WEEVNANVDPGTASQPGKHSYLGPGAGISGSVPGGGGVAINKAQRPGLPGANGSPLTSSVQENFRGFTYT
GESLMPQSMLADQSMDSDSDNENAVDDDEDDDEDEEEYEEDDDEENGIGSSRRECDVDMD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sch9 mutant is attenuated in rabbits (Wang et al., 2004).
References
Wang et al., 2004: Wang P, Cox GM, Heitman J. A Sch9 protein kinase homologue controlling virulence independently of the cAMP pathway in Cryptococcus neoformans. Current genetics. 2004; 46(5); 247-255. [PubMed: 15503029].