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HOG1

Victor ID 4755
Gene Name HOG1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Nucleotide GI 59805189
NCBI Protein GI 59805190
Protein Accession AAX08139.1
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name mitogen-activated protein kinase
DNA Sequence 
>gi|59805189|gb|AY775548.1| Cryptococcus neoformans var. grubii mitogen-activated protein kinase (HOG1) gene, complete cds
ATGGCCGATTTTGTCAAGCTCTCCATCTTTGGAACCGTATGTTTCTTTTATTGCTCTTTCTCTTTTCCCA
CCACCGTCATGATCTGCTCTTCCAACCAACCAACCTACGAACACGCGGCGTTTGTTTTTTCCGTTGGCCA
CTGGATCATATCGTGTTGATTCTGTCCATACGCCGGATGGAGGAGATCTGTAAAGGCAAGGCCGCGGACG
CTGATGGATGGGCTTTCTCCATGGATAGGTTTTTGAGGTTACCACGCGTTATGTCGACCTCCAACCTGTC
GGTATGGGCGCTTTCGGTCTCGTCTGGTGAGTCTTGTTTTTCTCAAGCAACTATCCTTTCATCTGGTTTT
TCAACCCAGCGTCGAAACAGGTCGTCCGACCTTTGCATGTCGATGTAGAGATGTGAACTGACAAAACCAT
CTTGTTTGATGCAGTTCCGCCAAGGATCAGCTGTCTGGAACTTCTGTGGCTATCAAGAAGATTATGAAGC
CCTTTTCAACCCCTGTTCTTTCCAAGAGGACTTACCGAGAGCTCAAGCTTCTTAAGCACTTGAGACATGA
GAACATTATCTCTCTTAGTGACATTTTCATCTCTCCTCTCGAAGATATGTGAGTTTTGCTCAATAGTTGC
ATATCAAAGAAGGGGGGAGGGGGCCTGCTGACATTTATCCAATAGCTACTTTGTCACCGAGCTGCTCGGT
ACTGACCTTCATCGACTCCTTACCTCTCGCCCTCTTGAGAAGCAATTCATCCAATACTTCCTTTATCAAA
TCCTCCGTGGTCTCAAGTATGTCCACTCTGCCGGTGTAGTCCATCGAGACTTGAAGCCTTCAAACATTCT
CGTCAACGAGAACTGTGACTTGAAGATTTGCGATTTCGGCCTTGCGAGGATCCAAGACCCTCAGATGACT
GGTTATGTTTCTACGAGGTACTACCGAGCACCCGAGATCATGTTGACATGGCAAAAGTATGATGTCGCGG
GTGAGTTTCAAGTTTTACGTTTGGGGGTGGTCTTTTAATTGGCGATCCATGCTGACCACGCAAAAAATCA
GTTGACATTTGGAGTACCGGCTGTATCTTTGCGGAGATGCTGGAGGGCAAGCCATTATTCCCCGGAAAGG
ACCACGTGAACCAATTCTCAATCATCACCGAATTGCTCGGTACTCCGCCGGACGATGTCATTCAAACTAT
CGCCTCTGAAAACACTCTCCGTTTCGTCCAGAGTCTGCCCAAGCGCGAAAAGGTCCCATTCTCCACCAAG
TTCCCCAACGCCGACCCTGTGTCTCTTGATTTGTTAGAGAAGATGCTCGTGTTTGACCCTCGTACCCGTA
TATCCGCCGCTGAAGGTCTCGCGCACGAGTATCTTGCGCCTTACCATGATCCTACCGATGAGCCTGTTGC
CGCCGAGGTGTTTGATTGGAGTTTTAACGATGCGGATTTGCCGGTGGATACTTGGAAGGTGATGATGTAT
AGTGAAATTCTTGGTAAGTCTCTGTGCCTTGCCTTTTTTTGGGTATTATACTAACGTCGGACTTTAGACT
TCCACAACCTCGGAGATATTTCACAGAACGAAGCAGAGGGACCCGTTACTGGCGAAGTCCCCGCTGCTCC
TGCCAGCTAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hog1 mutant is attenuated in mice (Bahn et al., 2005).
References
Bahn et al., 2005: Bahn YS, Kojima K, Cox GM, Heitman J. Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans. Molecular biology of the cell. 2005; 16(5); 2285-2300. [PubMed: 15728721].