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FHB1

Victor ID 4753
Gene Name FHB1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Protein GI 37783289
Other Database IDs CDD:183952
CDD:29979
CDD:99781
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name flavohemoglobin
Protein Length 504
Protein Note bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional
Protein Sequence 
>gi|37783289|gb|AAP41066.1| flavohemoglobin [Cryptococcus neoformans var. grubii]
MDAKKATIAIIALAAAATAYKVMSTTQEKKNTEGVCPATGQKRAGSTGCPFSSGLPLPDPGHRCDPNSIQ
EEYKVPEVPPLTEAQKDIIKSTAPILEQHGVTITTHFYKNMIRAHPELRDVFSESAQKLGHQPAALAAAV
YAYACNIHDLTPILPVVERIAHKHTSLHITANQYGIVGKHLIQAIVDILGDAVTPEVGDAWYNGYWNLAH
VFIKRERQLYDSAIEAGGWEGWRQFKVAKRVKESNEITSFYLKPVEGSGAPLPKFRPGQYTAVQIDIPGL
GYKQARQYSLSDAPNGEYFRISVKREDGVPVPTLSNPEVPFHPGWMSNVLHKDYQEGSIVNVASPFGDFY
YAPSDSSPTAPLVLLSAGVGQTPVMAMLNAQLAKNNEPNSPIKPITYVTVARSPKVRAFKDHVKKLSDVH
ENVKSRIFYSRPTDDVVEGQDYDFKGRMDLEKIKEDLYLGDKTAEYYICGPSKFMLNTRDKLQSLGVDPS
RIHYELFEAGNLSA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fhb1 mutant is attenuated in mice (de et al., 2003).
References
de et al., 2003: de Jesús-Berríos M, Liu L, Nussbaum JC, Cox GM, Stamler JS, Heitman J. Enzymes that counteract nitrosative stress promote fungal virulence. Current biology : CB. 2003; 13(22); 1963-1968. [PubMed: 14614821].