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CBP1

Victor ID 4751
Gene Name CBP1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Protein GI 7546976
Other Database IDs CDD:147151
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name calcineurin-binding protein
Protein Length 249
Protein Note anamorph: Cryptococcus neoformans
Protein Sequence 
>gi|7546976|gb|AAF63734.1|AF230799_1 calcineurin-binding protein [Cryptococcus neoformans var. grubii]
MTISSPQRPNGQPIEHEPTNTLALLLPHPTLFAPPVLDLLRAHYEHFGRIVHWAPVRGFGRAIVVFESEE
EAENAKRQGDWLKLDVPVGGEEKVDNEGKLKDIELVLRLHYLPPTTLNPDPATTHLAPPPLPHNFLISPP
GSPPEGWEPAAEEAPNRIILPEDLQRALETLELNSGSKADDGKEIILDEGGVRVQVEDTTKQERYGGEDY
EMGETLESGTGAWNLPSQSGGMGTPAFGVKIMPTTRPPL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cpb1 mutant is avirulent in both a rabbit model of cryptococcal meningitis and in a murine systemic infection model (Görlach et al., 2000).
References
Görlach et al., 2000: Görlach J, Fox DS, Cutler NS, Cox GM, Perfect JR, Heitman J. Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. The EMBO journal. 2000; 19(14); 3618-3629. [PubMed: 10899116].