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BWC2

Victor ID 4750
Gene Name BWC2
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans JEC 21
NCBI Protein GI 58397461
Other Database IDs CDD:141436
CDD:29259
Taxonomy ID 40410
Gene Strand (Orientation) ?
Protein Name white collar 2
Protein Length 392
Protein Note PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cl02459
Protein Sequence 
>gi|58397461|gb|AAW72938.1| white collar 2 [Cryptococcus neoformans var. neoformans]
MSLLAESLAGAKYMVATNDDRESSTNGAAEFLRRKRWPEILLKELVGSAVFCLKPTLILGSRQYQNGEAW
SWKIIYSSPSVYEMLGQRPADLEGRDFFDLVLVDDRPQLQSFFNSLLAPPLLNVEPTLLSSEGPDTLGGS
RTTYIRMLSAAPGPSRSDSSSRSSSGQRSLPQSNYGTPVGRILGPVVWEIRAHATGIGEDLGEAAGNGET
LRMAADGTVVSAIREGDGKHKAIWLMARQVGEGMNEDQKSLEAFLEVKLENERLLAELQELEEEVGMTVE
DSINNNQSASTPSSHSSTDTPPGGDKNKNKAGRPPKTNTQVSASGHKRQKSGTGGPAGASEGETMHVCVT
CGRTDSPEWRKGPLGPKTLCNACGLRWAKRNSTHIPKKDKQS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bwc2 mutant is attenuated in mice (Idnurm and Heitman, 2005).
References
Idnurm and Heitman, 2005: Idnurm A, Heitman J. Light controls growth and development via a conserved pathway in the fungal kingdom. PLoS biology. 2005; 3(4); e95. [PubMed: 15760278].