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SOD1

Victor ID 4744
Gene Name SOD1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. grubii H99
NCBI Protein GI 12698734
Other Database IDs CDD:48338
Taxonomy ID 178876
Gene Strand (Orientation) ?
Protein Name Cu/Zn superoxide dismutase
Protein Length 183
Protein Note Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; cd00305
Protein Sequence 
>gi|12698734|gb|AAK01665.1|AF324862_1 Cu/Zn superoxide dismutase [Cryptococcus neoformans var. grubii]
MVKAVVVLKGESYAHGIVCFTQESENAPVCITGEIKDMDADAKRGMHVHEFGDNTNGCTSAAPHYNPFKK
HHGAPTDSERHVGDLGNIQTNSCGAAQLDFSDKIISLYGPHSIIGGSFVVHASTDDLGKGGNEESLKTGN
AGARLACGVIGISTCQCYHSKLIVFAAVFLPKRTVTTYSWLNK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sod1 mutant is attenuated in mice (Cox et al., 2003).
References
Cox et al., 2003: Cox GM, Harrison TS, McDade HC, Taborda CP, Heinrich G, Casadevall A, Perfect JR. Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages. Infection and immunity. 2003; 71(1); 173-180. [PubMed: 12496163].