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snf1

Victor ID 4743
Gene Name snf1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans JEC 21
NCBI Gene ID 3256405
NCBI Protein GI 58265606
Locus Tag CNC01260
Genbank Accession AE017343
Protein Accession XP_569959
Taxonomy ID 214684
Chromosome No 3
Gene Starting Position 348155
Gene Ending Position 351352
Gene Strand (Orientation) +
Protein pI 9.74
Protein Weight 63138.52
Protein Length 596
Protein Note Supported by
DNA Sequence 
>gi|58271753:348155-351352 Cryptococcus neoformans var. neoformans JEC21 chromosome 3, complete sequence
TAATTACTCAACTATATCCCTATTTAGCGTAAAAGGAGGGATCAATAAGCCGCTCCTTCAGGAGCAAGGC
GGAGACAAATTGAAGAGCAGTCGAGACAGATTCTTATCAATAATAGAAAGAAGTAACGATGACTGATAGA
TTCTTTAGGCGTTCCCGGAACTTATTCATATCACCACAGTACGATAATAGATATTCTTCCACTGTATCAT
ATGCTGACATTTTGCATGGCATATGTCCTTAGGATGCAGCACTGATGACAGAAAAAGGATACAATCTGAC
ATTGATGAGACAACCATGGAAGGATAGTGGTTAAGAATAATGAGTGTTGTTGTGGTGGAGCGGCGTGACT
ATTGAAAGATGATGAGGACTACTACGAGGAGACTGCTGGTGCATCGCATCTATGCACGGACCTCTTGTCG
CCACCATTGCCCCTCCATCTTATTTGCGGTTGAGTCAACTAAGAACAACACTTTGAATTATTTCACTCTA
CTATCATATATATCCATTTTATTTTCGCTCCGTAGCCACTCTCGACTTCTTCGCTTTATCATCCCGAGGT
GAGTTACTCGGTTCCGTTGAAGGATTGTCTAGTGAGTAACTCGTCTGAAGGCGCAAAATTGAACGTTATT
GGAGACGGCCTTGGTAGCTAAACCGTTCGTTGGTCGACCTTGTCCGAGTATCCACTCGACAGAGAATACC
GAATCAAGATGGAAGCAGCCCAAACGCCTCGAAGTGTCTTAACTCATATAGGCGGTTGGAAGTTGGGTAA
GACTCTGGGTAGAGGTGCATACGGTCAGTCGCCATCCAGAAAGAATACAATCCAAGAGGCCAATGTTGAC
CAGAAGTTCTGTGTATCTAGCCCATGTTCGTCTCGCGACTCATAAAAATGGACACCAAGCAGCTTGCAAA
ATCCTTCCAGCATTACATAAAGACCCCGGGCTTCCAGTGACGTGGGATGAGACTATCGACGCAGTTGAAG
CTCATAAAGAAGTGGTACTGCTCAAAGCTCTTTGTGGAGCAGGCGTGGAAGGTATCGCCGGATTGGAAGG
AGTGGTGGAAGAAGGTGGCTGGACGTAAGGTCTAATCTAATGGGGACTTTTCGCTGTCACTAAAAGTGTG
CATAGTTACGTTTTCCTTACCCTTTATCCGTGTTCCATATCATCCATTTCTAAACCTTGGGCTTCTGATG
CTGTCGTCATCTTTTTCCGCCGGTTGCTCCATACCGTTCGTAACCTGCACCAACTCAATGTCAGTCACGA
GGATATCAAGCGGTCCAATGTCCTTGCAGACTCCCAAGGTTCCCCTGTGCTTGTCGATTTTGGGTTTTCC
CATTTCAAAGCAAATGGAGGTTATGTCAAGAGTGCTGGCGGAACTTTGGATTACTCAAGTCCGGAGAAAA
CTGCCGTGTGTTTATCCCGTAATTTTACATATCAGATTAGGCGCTAACAAATGCCAGGACAAACATTACG
ATCCCAAAGCCAATGATATTTGGGCTCTCGGTATTTTACTCACCAAGATTCTCTGTATACAACATCCATA
CGCACACTCTTATGTCGATGACACTAGCACCACTGTCAAGCGCCGTATCTTGACAGGTGATGCGAAATTC
CATTGGAAAACTGATCACCTGGTTCCAGGTGGCGTTGCTGAACTTATCATGGGAATGCTGGAGCGCGATC
CCCAGCAACGCTGGACAGTGAGGCAATGAGTATCTTTCTCTCAGCTCAATATTGACGATTTTATTTAGAT
AACACGTATACTCGGACACCCATGGCTCAGAACAAAATACCCTGATCTAAGACCTTTCCAGCTCCCCTCG
TATGAGCTCAAGCTTTTACATAAGCCATCACAGAGTGTCATTGAAGATCTATGCTTTCTAGCCTACCTCA
ATGGCGAATTCGCGCTTTGTGAGACTTCGATGAGGATAGAAGAGCATCTAGAAGGTAAAGAGCCCTGTTG
GGAAAAAAGATGGGCAGGGATGTTGGGATCCTGGTCTCAAAGAGCGGAGATGGACTGGCAGGACATACCT
ACTGCTATCACTCCCCTTCCCAAATCTAGAAGCAGTGAGTTGAAAGTTAATTTGGGAGAAGTTTACAATT
CTGACGATTATTCTTAAAGGTTTTACTCGTGTGAACGGTCCTACGAAGGCCAACGCGATAGGAAATTCCA
AAGGGGGAATTTTAAAGGAAATCCATCTTCTTCCCAACGTGAGATAAGCCTGATATCACAGGGACCGATT
ACTGATTATTTTCAGGCGCAAGCTCTCACCACATTAGGGTCAAATGGAGACATTAAAAAAGGACTCAGGC
CCGCCCGCTCGCGATTCTATAATATGAAAACTAAAAATGGCGCCCAGAATCTCTTGGTCTGTAGTCTTCG
GCCAGGCATACATACTCAAACTACGCTGCAAGAGAAATTTGTGCCGGACGATTTGATGGCCGCTACGAAC
AACCAATCCAGCAAAGCTAAACCCGGTATCGTTCGGGTCAAAAAGCCCAAGGCTAAGCAAAAATCAAAGG
TTAGCGCTAGCCCTTTATTGTGATTCTTTATATGTCATTGTCGCTGTTGATCGCTGATCGGCAGCGCGTC
CAGGCGGATTTCAAGATCTTCATTAGCGACACAGATAATTCTGGAGAAGAGAACGAAACCGTTGAAAAGC
GGCAAAATCAGCAAGGACCAAGGAAGCTCGATAAAACGGGTGCAAAGAATTTAATTATTGGCGAGAGCCC
TACATTGGCAGCCTTGGTGACGTGAATGACTATCGAACAAGACTGTGGGATAGTTTAACAGCTGACAACC
TAAAGAGATAGTAAAGAGGGGTTCATAACTTCCGTCCCAGACGAGCAAATGAAAGGTTCGTATGAGTATT
CAATGGATTGAGCCCACTTACCAGATCCATCAGGATTATTTCTGTCCAAGCCAGACCCGCCACGCGCGCG
ATGCACACAACGTCGCTCCCCTCGCTTGCAAGAAGAAAAGAGAATTGACCTTAACTAGTGTTTACAGTGG
TCTGTCGGTCAAAACTTAGACACTATTGGAGGCTTTGTTTATTTTCCCTTTTCTGATGGTTCTTGAGATT
TTCGAATATACTTCCTGTGATCGATAGACCAGTGACACCTTAGCACACCTGATCATCACCATTCTACGGA
CGTAGTAAGCGATGGCTGACAAGCAGATAGCTCCTTACGCTCTGCATG
Protein Sequence 
>gi|58265606|ref|XP_569959.1| SNF1 family protein kinase [Cryptococcus neoformans var. neoformans JEC21]
MEAAQTPRSVLTHIGGWKLGKTLGRGAYAHVRLATHKNGHQAACKILPALHKDPGLPVTWDETIDAVEAH
KEVVLLKALCGAGVEGIAGLEGVVEEGGWTYVFLTLYPCSISSISKPWASDAVVIFFRRLLHTVRNLHQL
NVSHEDIKRSNVLADSQGSPVLVDFGFSHFKANGGYVKSAGGTLDYSSPEKTADKHYDPKANDIWALGIL
LTKILCIQHPYAHSYVDDTSTTVKRRILTGDAKFHWKTDHLVPGGVAELIMGMLERDPQQRWTITRILGH
PWLRTKYPDLRPFQLPSYELKLLHKPSQSVIEDLCFLAYLNGEFALCETSMRIEEHLEGKEPCWEKRWAG
MLGSWSQRAEMDWQDIPTAITPLPKSRSSFTRVNGPTKANAIGNSKGGILKEIHLLPNAQALTTLGSNGD
IKKGLRPARSRFYNMKTKNGAQNLLVCSLRPGIHTQTTLQEKFVPDDLMAATNNQSSKAKPGIVRVKKPK
AKQKSKADFKIFISDTDNSGEENETVEKRQNQQGPRKLDKTGAKNLIIGESPTLAALVTDSKEGFITSVP
DEQMKGLFLSKPDPPRARCTQRRSPRLQEEKRIDLN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: snf1 mutant is attenuated in mice (Hu et al., 2008).
References
Hu et al., 2008: Hu G, Cheng PY, Sham A, Perfect JR, Kronstad JW. Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection. Molecular microbiology. 2008; 69(6); 1456-1475. [PubMed: 18673460].