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nmt

Victor ID 4738
Gene Name nmt
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans B-3501A
NCBI Gene ID 4939624
NCBI Protein GI 134118644
Locus Tag CNBN0070
Genbank Accession AAEY01000065
Protein Accession XP_772024
Taxonomy ID 283643
Chromosome No 14
Gene Starting Position 26988
Gene Ending Position 29604
Gene Strand (Orientation) +
Protein pI 6.03
Protein Weight 61508.93
Protein Length 595
DNA Sequence 
>gi|134119137:26988-29604 Cryptococcus neoformans var. neoformans B-3501A chromosome 14, whole genome shotgun sequence
GATGTCCAGTCTACCCAACCAATCCCTCCCGGCAGAACCGCAACCTGGCGTAGAGGAAGTCCTCGACAAA
TTCCAGAAACTCGGAGAAGAAGCCGTCGAGGAAGATGCCGGTGAAGATGATGCCGATGCCGCTGAGGAGG
ATGGCGATGAACAGCCTGAGGATGGTGAGGGAGGGGAAGGTCTTGGAGACAAGAAGAAGAAAAAGAAGAA
GAAGAAGAAGGGAAAGGCTAGCAAAGCTGTCGAAAAGCTCAAGTTCGTGTCTTTTGTGTTTCCCAACAGT
ATCATCTCTGACTTCGCGTCGTGTAGGACTATCGCTACAGGTCAAGCCCCTCAGGAAGTCATCAATGCTG
TAAGAGGGCAGATGGATTCCTCTGATAGCAAGGCCGCTACCGACGGTAAGTTTTGTCGTCCCAGTCCATC
CCATCTCGACTTGCCCCACCCAATTTTCAAGGCTGACAAAAAAGACGGGCTGTAGAGGAGATTCGACGTG
CTTTGAAAGCGGCGGATTTGATGAAGATCCTTGATGGTAAAATAGCTTTGGGCAATAAGTCTGGTACCAA
GAACCTCGGCGAGCACAAGGTAGGCACTCTTTCCCCGACCTCAGACCATTACCGTTTCATCTGCTGTTTC
AAGCACTTATGCCTCTCAATAGTTTTGGAAGACCCAGCCCGTTCCTCAGATCACCGGTTCCGGCGCTCCA
GCTCCTATTGAAGAAGGCCCTATCGACGATCCCAAAACCCCCGCAGACGTCAGACAAGAACCTGGGGTTT
TACCCGCTGGATTCGAATGGAGTACTATCGATATCAATGACGAGGAGCAAGTAAGTTTCTGCCTCAATCT
TTCGTGTCTTTTATGATACCGTTAGCTGCAGCTCATTCATATCCTTTTACTCAGAGTAAAGAAGTTTACG
TCCTGTTATGCGAAAATTATGTAGAGGATGACGATGCCATGTTCCGATTTAACTACTCTAGAGAATTCTT
ACTCTGGTACGTGTATACTAAATCAGCAAGTCGGGTTTTACGCTCGCTAATATCCTTGTTCAGGGCACTT
ACCGCTCCGGGATACTTGCCAGACTGGCACATTGGTGTACGCGTACAAAAGACAAAGAAACTTGTTGCTT
TCATTTCTGGTATCAAGATTGACATTCGCGTTCGTGCCAAGTAAGTCACATCTCTCTACTTTTTACGTTG
CAATCAATACCCTAGCAGCCTAAATGCCCTGTATGCTGACCTCTCCATCCACCTCCCCTTTAGGACATTC
CCCGCGGCCGAGATCAACTTTCTTTGCGTCCACAAAAAACTCCGATCCAAGCGCCTCGCACCGGTATTAA
TCAAAGAAGTCACCCGACGAGTCAATTTGACAAATATCTGGCAAGCCATCTACACTGCTGGTGTCATCCT
CCCTACTCCTATCGGTACCTGTCGGTAAGTCAAAACATGCTGCTCTCCAGTCCCCTTCCCATGCATTTTC
AGGACTGACGTATTCGACCCCCAATTTCATCCCTATCTCCACAGATACTTCCATCGCAACCTCAACCCCC
CCAAACTCGTCGACATTGGCTTCTCCCCCCTTCCCCGGGGAAGCACCATCGCTCGTCTCGTACAACAATA
CTCTGTTCCCTCTCACCCCCGTATCCCCGGTTTCCGCGAGATGAAAAAGGAAGACGTGCCCCAAGTTGGA
GCTCTGTTGAGGAGATATTTGGATAGGTTCGATGTGGCGCAAGCGTTCAGGGATGATGACGAGGTTGAGC
ATTGGCTTTTGAGTGGACAGGGGAAGGAGGTGGGCGGGAGGAGGGTAGAGCAGGTCGTTTGGGCCTATGT
CGTCGAGGTGGGTTTTATCTCTTTTCCTTTTCTTTGTCCCATATCCAAGCCAACTTTGACCCCTTTGCCT
TTTCTTTACAAAGGACCCAACAACCCACCGTATCACCGACCTCATCTCCTTCTACGCCCTCCCCTCAACC
ATCATGAAACACCCCAAACACAACTTGCTCAATGCCGCTTACATGTTCTACTACGCTACCGACGTCGTCT
TCCCGCCCTCATCCTCTTCTGCCAACTCTGATGTCGATGTCGATGCCAATGCCGGAGAAAGCTCGGTAGC
GGCTGTGGGTACGGGAGGGGAAGATGCGAAAACGAAGAAAAAGTTGGAGACGAGGTTGAATGCGCTGACT
GCGGATATACTGATCATCGCCAAACAGGTGAGGCTCTTTACACCTCCCTTTTCCAAACGATGGAGAAAAC
TCATACCTCCTCTTTTCCTTTTTACCTAGGCCGGTTTCGATGTCTTCAACGCACTGACGTTACTCGACAA
CAACATGTTCTTGCAAGAACAAAAGGTGAGCAACCCTCCCACTTTCATACTCCCATGCTAACCCTTTTTT
TTTTTCTCGTCATAGTTCGGACCAGGCGATGGATACCTCAACTGTAAGTCCGTCCCTCGTCCCCTGTGCA
TTAAATTCCCCTATCCTATTCGCATTCGAAAATTCAATGACCATCACGCTGACCAAACGGTGATTATCTA
TAGATTACCTGTACAACTGGAACTGCGCCCCTATCGATGGCGGACATCATTCCACAACCGCCAAACAAGG
ATCCAAGATCGGCGTTGTCATGCTCTA
Protein Sequence 
>gi|134118644|ref|XP_772024.1| hypothetical protein CNBN0070 [Cryptococcus neoformans var. neoformans B-3501A]
MSSLPNQSLPAEPQPGVEEVLDKFQKLGEEAVEEDAGEDDADAAEEDGDEQPEDGEGGEGLGDKKKKKKK
KKKGKASKAVEKLKTIATGQAPQEVINAVRGQMDSSDSKAATDEEIRRALKAADLMKILDGKIALGNKSG
TKNLGEHKFWKTQPVPQITGSGAPAPIEEGPIDDPKTPADVRQEPGVLPAGFEWSTIDINDEEQSKEVYV
LLCENYVEDDDAMFRFNYSREFLLWALTAPGYLPDWHIGVRVQKTKKLVAFISGIKIDIRVRAKTFPAAE
INFLCVHKKLRSKRLAPVLIKEVTRRVNLTNIWQAIYTAGVILPTPIGTCRYFHRNLNPPKLVDIGFSPL
PRGSTIARLVQQYSVPSHPRIPGFREMKKEDVPQVGALLRRYLDRFDVAQAFRDDDEVEHWLLSGQGKEV
GGRRVEQVVWAYVVEDPTTHRITDLISFYALPSTIMKHPKHNLLNAAYMFYYATDVVFPPSSSSANSDVD
VDANAGESSVAAVGTGGEDAKTKKKLETRLNALTADILIIAKQAGFDVFNALTLLDNNMFLQEQKFGPGD
GYLNYYLYNWNCAPIDGGHHSTTAKQGSKIGVVML
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: nmt mutant is attenuated in immunosuppressed rabbits (Lodge et al., 1994).
References
Lodge et al., 1994: Lodge JK, Jackson-Machelski E, Toffaletti DL, Perfect JR, Gordon JI. Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. Proceedings of the National Academy of Sciences of the United States of America. 1994; 91(25); 12008-12012. [PubMed: 7991574].