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MAN1

Victor ID 4736
Gene Name MAN1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans
NCBI Nucleotide GI 9965933
NCBI Protein GI 9965934
Protein Accession AAG10203.1
Taxonomy ID 40410
Gene Strand (Orientation) ?
Protein Name mannose-6-phosphate isomerase
Protein Note contains promoter and 5' UTR
DNA Sequence 
>gi|9965933|gb|AF291701.1| Filobasidiella neoformans var. neoformans mannose-6-phosphate isomerase (MAN1) gene, complete cds
TAATACACATCGTTTAACTGTTCCTTATGATAGATGTCTGCGTGTTGTACAATACGATACATGTTTGATG
GTTGTTTGTTGATGCTTGATGACGGCGGATGAAAGATGATGGCTGACGGGTTGTCCAGAAGAAGGTGGTA
GGCAGTGATAATGTAGGTAGGCAGACAAACAGCAGGCAACAGAGACGACTTTTATTAGCCCCACGATCCC
AGTACAGTCAATAATAGACTTTTTCAGGTCTCGATCTGCTCTCTGCCTGCATATTTCCTGTTCCGAAAGA
TCAAAGATTAAAGGATCAAAGTCAAGGAACGGTGCACGCGATAAGCGCAGTAGGCGAGACCTTCCGGGCT
TCCACGTGCTCAGTAATCTGCGGTAGAGGCGGCAGAGCCCACTTACCGCTAATCGTGTCCCTGAAAGTAT
GACGATCCGATTAAGGACGACCCTCTGAAACCGAACTTCGTTGGGAATTTTGACGCGTTTAGCGTTTTAC
CCGCGGCATATCCACCATCACAGCCAGGCAGAGCAGATCAAATCCTCAACAAACGTGTCTTTTATCACAC
CTTTTATATTCACATCCATTCCCATTCGCCTCCACAGCTGTCTATATCCCATTCGCAATGTCTCCTTCCG
TGTTCAAAATCTCGCCAGGTATTAACTCATACGACTGGGGCAAGAAAGGCTCAGCATCCCTAGCCGCACA
GCTTGCAACCACCTCCATCCCAGATTTCGCCATTGATGAGGACAGGGCCTACGCTGAAGTACGCGTTTAT
TTAAAAGTTTAGTGATTATACGCTAATGCGAATCAGTTATGGATGGGTACTCACCCCAACAATCCATCTA
GGTTATCGGACAACACTTTACTCTCTGAACACCTCAGGTCTCATCCAGAGCTTATCGGCACCACTGTGTC
TTCCAAGTTTGAGGACTGCAAGGACGGCTCTTTACCCTTCCTATTCAAGGTCCTGAGTATAGGTACTGCT
CTCAGTATACAGGCTCACCCTGATAAGCCGCTTGCGAAGAAACTCTTTGATGAGAAGCCTGATGTCTATA
AAGTGTGTCACTCCCTTCTACTCCATGTTGGGCGCCAAACTCATCGAAGGCGCTGTAGGACCCTAACCAC
AAGCCCGAGATGGCCATTGCCCTTACTCCTTTCCTTGCCTTCCTTAATTTCCTTCCCCTCCCTGTGCTTC
TCTTGCACCTTCTGACCGTCCCCGAACTGCAAGAGTTTGTCGATTCTTCTCTCACCGAATCCCTAGCGTC
ATCGCTCGACTTACCTACATCTCAACCGCCTGATTCTTCCCTTTTCAAACCTACGGAATCCCCAGCCACT
GCCGAGCAGAAAGATATTCTCAAGCAGATTTTTGCCGCTCTTATGTCAGCAGATAAGAAGCATGTTGAAG
AAGCTATCTCCAAACTTATCAAGAGATATAAAGCGAAGCGAGATATCAAGGAAAACGAGAAGGATCTTGT
GGACTTGGCTTTGAGGCTTAATGATCAGTACCCTGGGGATGTTGGTGTCCTCTGTGTGTTCCTGTTGAAC
GTCGTGGAGCTTAAGAGAGGCGAAGCTGCTTTTCTTGGGGCCAATGAGCCGCACGCCTATATCGAGGGTG
TGAGTAATTTCATGCTTTCAGGGGAAAGCTGATTGATGTCTGACTTAACCAGGATATCATTGAATGTATG
GCTACATCCGACAACGTCGTTCGCGCGGGTCTTACCCCCAAGCTCCGAGATGTCGACACTCTTGTCTCCA
TGCTCACATACGAAGCTGCTCCAGGGAACAAGCAACTACTCCAACCCACCTCATTTCAAAAGGGTGACGA
TACTACCAAACTCTACGATCCCCCTATTGCTGAATTCTCTGTCTTGCGTACTGAGCTTTCTAAAGGAATG
AAGACTTCTCACCGGCCTGTGGAGGGTCCTAGCTTGTGTGTTATCACTGAAGGTGAGGGTGTTGTCAGAG
ATGGAAATGATCAAACAGAGTTTGTCAGGGGTGATGTTATCTTTGTGGGAGCTGGCAAAGAAGTGGAATG
GGAGGCGATTAAGGGATTGGAGATGTTTAGGGCCTATGTTGAGGCTTAAAAAACCCCTTGTTGAGGCTTA
GAAAAAGACCTTGTGGAATCCCGGTACCGACAAAGGCAGTTGCTTGAACATCTATAGAATTATTAAGGTA
TAGGCCCCGTATTGCAGTCAGTATGTATCATGATGCATGTCTCTCATTGAATCTTCTGGACAATCCTATC
AGTCAATATGTCGCAACTACAAGCTGATGGTAAGCACACTGACTATCCATTATTGTTGTCATTATCCGTC
CGTCGTTGGACACTTGCAACAACCATAGGCAGCGTCAAATGATGACGTGGAAGTAAGACTTTGCCTGATT
ATTAATAAAAAAAATTGTTGTTGATGAATTGATTATACTTGTCGGAAAGCGACGCCTGGAATTTGAGGCG
AGCAGACGATGACAAGCGAACTGCACTGCGCATGATGAGGAAGCCAGCGTGCTGAGGTAGCGCGCTCTCG
CTTTATAGCCCAATAGGCCAAGCATGGTTCGTTTGTTTTGGTTTAATAACAGGAGACCTCCACCTCCA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: man1 mutant is attenuated in mice and rabbits (Wills et al., 2001).
References
Wills et al., 2001: Wills EA, Roberts IS, Del Poeta M, Rivera J, Casadevall A, Cox GM, Perfect JR. Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity. Molecular microbiology. 2001; 40(3); 610-620. [PubMed: 11359567].