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CPRa1

Victor ID 4727
Gene Name CPRa1
Sequence Strain (Species/Organism) Cryptococcus neoformans
NCBI Nucleotide GI 13603796
NCBI Protein GI 13603797
Protein Accession AAK31936.1
Taxonomy ID 5207
Gene Strand (Orientation) ?
Protein Name pheromone receptor CPRa1p
DNA Sequence 
>gi|13603796|gb|AF250141.1| Filobasidiella neoformans pheromone receptor CPRa1p (CPRa1) gene, complete cds
TTTCACAGCAAGTTCGCCATCATGCTTCATTTCCGTCCGTCCATAGCATAACTTACCACATATATATGTT
GTTTCTGGTTTTCTTTCAAGGTAATCTTCTCGACTTCCTCTCTGGTTAACACTGTCATTGCATGTCTAAA
GACATGCTCTAGAAAGCTACCGACTGTGCATAATTCTTCGTAAAAGGCATCCCTGTTGGTCGTGTAAGTC
GTCGCACTGGCCCTGCGCTTTGACGTTTGTATTGAGTGTCATGTACAAAAGACAAAAAGACAAAAAGACA
AAAAGACAAAAAGACAAAAAGACAAAAAGACAAAAAGACAAAAAGACAAAAAGACAAAAAGACAAAAAGA
CAAAAAGACAAAAAGACAAGAAGGCAAAAAGGCAAAAACACAGATATGTACTACTACGTGTATAAACGCG
TGAAGGCGGACATATATTATGCTCATATCCATATGTATATACCAGCCCATCGTGTACTCCGGACGTACTA
TCATCGTCAGAACTCAAAACCGAACAGCAACTCCTCACATACTCCCACTCTTTGTTTATTCTCCATAACC
TTAATTACACAAGGAACATCTAGTTTTCAATCCAGTTGCCCGCTCCATTGATGTCTGGAAGCTGATAAAA
ACATATTGGTCCCTGCTCCTCAAAGGCCATCTTTCAAACCACGTATTAACAAGACGGACGCTTGGCCCCC
GTTATCATGCTCCACCCCGACTATCCCTTTTGGAATCTCACTGCTTTAGTCCTTGTTCTCCTACCTGCGC
CCTGGCATTGGCGTGCTCGTAACATTGCGACGGTATCACTGGTTGTCTGGTTGACTTTTGCCAACCTTTG
CGGTTTCATCAACACTATCATTTGGGCCGGCAATTATGCGGATAAGAGCCCCGTTTGGTGTGATATCAGT
AGGTCATCATCACCCTCGGCTCTGCAGATGCTGACTCTACCTTGTTGAAGGTAGTAGAGTGCCGCTTCTT
GTTGGCTACGCAATCCCTCTCTGTTCTCTATCTCAGATGCGTAGATTGGAGTCAGTTGCGTCCACGCGCC
GATCGCTCATGTCTTCTGGAATGCGCAAACGACGCGTATGGGAGGAAATCATCATATGTCTCCTGCTCCC
TGTAATATTTACTGTACTCCAATATGTCGTGCAAGGCCATCGCTACGATATTATTGAAGGCGTTGGATGC
AGCAATCCAACTTTTATGTCAGTCCCTGGCCTGATGATACGATTTATTGTTCCCATGGTTGTGGCCGTAG
CATCCCTCATATTCGCTGGTACGTACCATATGACTCGAATATATTGAGCATCAGCTGATTTTTTCTATGT
ATTATAGCCCTGGCAGTGCGATGGTTCTTGATAAGGCGACTCCAATTTCGTACTATCCTCGCTTCATCTG
ATGCTAAATTGTCAATCGGCCGGTACTTTCGCCTAATCGCTCTGGCAGTGACAGATAGCACCGTTGTGCT
AGTGGTCATCGTGTATGCTGCCGCGAACGCTCTATCTGATTCCTCATTACCCATGCGACCTTACCGCAAT
TGGGCATACGTCCACGAAGATTTTTCACAGGTATCACAATATCCCGAAGAACTGTTCGCCTCTTCCTGGC
CCGCTGTTGTCATGAATGTCTATGCGCCAATTTTGTATTCCATACTCTTTTTCACATTTTTCGGGTTTGG
AGAAGAAGCTGTATCTGAATACTTAGCCATTGGAGACAAGGTCATGCAGCTATTGGAAATAATGGGCTTT
AAGGGCAAAAGGTGAGTGGATTTATCCGGCGTCGAGCGCATATCCGTAACTGATACGATATGCAAATAGG
TCCGGACCGGTCTTCAATGACCTTCGTATTGACCTTGGATGCAAGATAGTGCCTGCTTTTAATGGAAATG
ATCTGGAGAGTACACCCTTAGGCAACTTGCGAGATGATACAAGCGAAAAAGGTTTTCAGGATTTGGAGTC
AAGAGCAGTGAAGGCGACTCCGCTGAATAACATGGGTATCGCCGTGACAGTAGAAAGATCGGTAGTAGCT
TAGTGGGGCCTATGCAGTGAATTAATTATCCTCATTATCAATCTATTATGGCGCTCCTTGGAAGCTCTAT
GCCGCCTAGTACGTGGTTAGCATTGCTCAGATAGAATGAGATATAATTATTATTAATGATTACAACCTTC
TTCTGAAGGTAGCTACGTAGACAGAAATGCACAGTTATGTGGTTTGATAATATGCGCGCAGTAGTAGAGT
ATCCCAGGCAAGCGCAAACTTAGCTGCGCTCAGCAGATATCACGGATAATCTTCGCACTTCTGTTTTTGT
TAATTGAAGAAGTCTTAATCCCCGTTGTCGCTGGCATTGTGCAGCCATAAGCTGTGCACGTATGAATGAT
CCCTTTTAAAAACTCAAAATAGATTTCTTCCTCAGAAGAAAGACTCGAGATTCGCTACCACAGTGCACAT
CTTGACTGGACTTTCTGGCATATTCACCTCTTTCAGCAACCCGCTGATGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cpra mutant celss produce smaller capsules in the brains of mice than wild-type cells, is also attenuated for virulence in mice (Chang et al., 2003).
References
Chang et al., 2003: Chang YC, Miller GF, Kwon-Chung KJ. Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence. Infection and immunity. 2003; 71(9); 4953-4960. [PubMed: 12933837].