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CIR1

Victor ID 4725
Gene Name CIR1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans B3501A
NCBI Nucleotide GI 108802599
NCBI Protein GI 108802600
Protein Accession ABG21303.1
Taxonomy ID 40410
Gene Strand (Orientation) ?
Protein Name iron regulator 1
DNA Sequence 
>gi|108802599|gb|DQ631833.1| Cryptococcus neoformans var. neoformans iron regulator 1 (CIR1) mRNA, complete cds
ATGCCCGAAACGCATACCTCCGCGCCTCAGGACAACGAGCATGAACCTTCAATTGGCAGTCGATTCGAAA
ACCGATTTGGTCCCGGGTGGAGAGTAGGGTTCGACAATTCTAATGAGCGAGGAGGCGTCGACGAAGATGC
TGCCGAAGACTCACCCCCTCCTCGTCGAGAATCACTTGATACATCGGATAAGGAGGTCGAAGCGGCCGAA
ATGGAAACGCCAAATGTTGAGAGAGATGAGTTGGAGTCTGATTATGGGGAGCCAGTTCAACAGCAAGGAC
ATGTTGATTCTGAAGAAGAGCTGGATCAGAAAGAATTGATCAGAAGGGCTGCAGCCAGAAGAAGACATCA
AAACAAGAAAGAAGAGCAAGGTAGTGATGGTCAGCCATCCGCGAAAAAGAGAAAACCCCTCGCCCCTGCC
AACGCATCTCCATTGCCTTCTCCGCCTCCTTCCACTGCTGTCACGGCGTCAGCTCATCCTTCTGCTGGAA
CTTGTCCTGGTGACGGGAGATGCAATGGTGCTGGTGGCAAGGCTGGCTGCGAAGGTTGCCCAACCTACAA
TAACTCGATCGCTTCTGGATTGGTCTCCGCCAGTAATTCCCACGCAGCTTCACATCCTCCCAATGTGTCT
GAAGGTAATGAACGTCCCGTTCGAAACATTTATGATCGCGAGCATCGTCCTTACGGCTTCGACCGTTTCA
TGGAGAACAGTATGGGTAACGGTTTGGCTCCAAGGGCTTTACCTCGTCAGAGCCCTGATCGACGACAGGC
TCACCCTTCTCCCGTAACCACTCAGCCGTTGATGCATCCGACTTCCGAGAAGGGAACTCCAACAAGGTTC
TCACCGGATAGCGACGTCGAAACTCCTGCCGCTCCTGGTGGTAATGGATCGGGGCTTGCTGCTACTCCCG
TTGGAATGAGCTGCAGGAATTGTGGGACAAGTACCACTCCTTTGTGGCGAAGGGATGAAGAGGGTCGACC
TCAATGCAACGCATGCGGTCTTTATCACAAGCTTCATGGTGTTCCTCGACCCGTAGCTATGAAAAAGACT
GTTATTAAACGACGCAAGCGTGTTCCTGCTGTTGGTAGTACTTCTACTGGCGGTCGTGGCACAAATGCCG
AGCTCCCTTCACCTGCTAGTACGCCCGTTTCCGTTCCGACGGTCACCGCTCCGCCTCCTCACGTGGCACC
GCCTCTTGATGACAAGGCTCACCGTACCTCTCCTCCTTTTGGTCACCGTGCTTCTCAACCTCACTCGGAA
CACCGAATCAACCATTCTCTAGGTCCAGAGGCATATGGTCTTGCCGGTAGGTACGGTAAGCCTTCTACCC
CTGCTGGTATGAATTTGCCTAGCTCCGCCTCCACCTCGTCTTTGAATCTTCCCGAAAGGAAGAAGCCTTG
GTGGCAAGAGGGCCGAGAAGGCCGAGACCGTGAGAAGGAAGAGAAAGACAGAGAAGCCAGGGAACGCGAA
GGGCTTGCTGCAGAAGCACTTCTCACGATGGCGCCCGCTGCTAATGGCGGACCTTCTCCCGAAAAACGAG
CCGAAAAGTCCTCCGGTGCTGGATCTGTGCCTGCTTCTCAATCTAGGCGTACATCCATTGACGTCGACAT
GGCTGATAGCGAGCCCCGAGGTATTAAGAGAAAGAATGAGGAAGAGTCACGTGACATTCGCGATCCTCGT
GCTTCTATGAGCCTTGGCCTTCACAGTATGGACCGTGACCGAAATAGGTCCAAGGACAGGACATTTTCTC
ATTCTCCTCTTATCAGCACCGACCCTCGCTCTGTTCAGCCCTCCAATTCCCACCTTCCAAGCTCTCGTCT
AGGCCAGCCCCCCACGAGCTCAGCATCTCCTTATCCTGCCACTACCCAACAGGGTGCACCTAACCGTTAC
TCTGTATACGGTCCTACCACTCGCGACCCACTTGCCGGTACCACTCGCGACCCACTTGCCGGTAGCTCCC
CTTACTCTTTCAACGCTTCGCGATATTCCAACCTTCACATGCGTCGCGACCTTTCTCCTTCTGTTGGTGG
CGCCACCTCCAAGCCCAATGTCCTTTCTCCCCCACGACGTGCATCACCCGCGCCTGCTCCTGATCCCCGG
GAACGATTTTATCCCTCACCGTCCGCCGCCGCATCTGCCGGCTCGGCGCCGGCCAGTGTCAATGCTGCAA
TGGCTGGCTATGGTCACTACTCTATGAGCCGCAGGGAGTTGCAGGAACACCGAGAGCAGCTCAAGGAAGG
CAAGCGATGGCTCGAAGCCATGATGGCTAAGACGGACAAGATGCTGCACATGGTGGAGAACAAAATGGCT
TTGACTGTTGAGATGAGCTCTGGTCCTTCTGTAGCTGGACCTGGCGACAGGCCATCTTTGTCTTCCAATG
CCAGCCCCGTCCCCCCACCTGGTGCAGTCCACAAGATGAGCGACGATTGGGAGTTTGAGGAGAGAGAAAG
ACAGAGACAGAAGGAAATTCAGAGGCTTGAGCAGGAAAGGGAAATGGACCGAGCTGAGAGGGAGAAACGT
GAGAGGGAAAGGGAAAGGGAAAGACCTGGATCTTATGAGGATGTCCGTGGGCGCCCTAGAGATAAGTCGG
AGGCTGAACGTAACCGTGACATCCTTCTCGCGAGCCGTAGAGTTTCAGCGGTATCCCCTAACCCGGCTAC
TCGAGCCGCTGCCGCGTCTCGTGAGAGTGCGGCGTCTTCCAACGGAAGCGCTCCTCAACAAGGTGAAAAG
TCTCACGGCGGTACGAATGGAGTTTCTGGCGGGAAGCGAGAAGGTAGTCAGTGGGACGGAGAACCCGTGA
TGTCTGGTGTGCCTTTGCCTAGAAGAGAGCAGCAAAATGGGATTGGGAGCAGATTGGGGAGAGGATTGTG
GAGTTTTGACGTTAGGAGTTGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cir1 mutant is avirulent in mice (Jung et al., 2006).
References
Jung et al., 2006: Jung WH, Sham A, White R, Kronstad JW. Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans. PLoS biology. 2006; 4(12); e410. [PubMed: 17121456].