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CFT1

Victor ID 4724
Gene Name CFT1
Sequence Strain (Species/Organism) Cryptococcus neoformans
NCBI Protein GI 74684770
Other Database IDs CDD:34762
CDD:146015
Taxonomy ID 5207
Gene Strand (Orientation) ?
Protein Name Protein CFT1
Protein Length 1431
Protein Note teleomorph: Filobasidiella neoformans
Protein Sequence 
>gi|74684770|sp|Q5KFS0.1|CFT1_CRYNE RecName: Full=Protein CFT1; AltName: Full=Cleavage factor two protein 1
MHALHQTLLPSSSIHHSLFLPHFTPSTIYPLPKPPAALDTLDVKVIGNLVVAGAEVLRVFEIREESVPII
ENVKLEEDVAEGEKDVQMEEVGDGFFDDGHAERAPLKYQTTRRLHLLTQHELNGTITGLAATRTLESTID
GLDRLIVSFKDAKMALLEWSRGDIATVSLHTYERCSQMNTGDLQSYVPLLRTDPLSRLAVLTLPEDSLAV
LPLIQEQSELDPLSEGFSRDAPYSPSFVLSLSDMSITIKNIQDLLFLPGFHSPTIALLFSPMHTWSGRLQ
TVKDTFCLEIRTFDLSSGTSYPLLTSVSGLPSDSLYLVACPSELGGIVLVTSTGIVHVDQGGRVTAACVN
AWWSRITSLKCSMASVSQKLTLEGSRCVFVTPHDMLLVLQNGAVHQVRFSMEGRAVGVIEVLDKGCVVPP
PSDLTVAGDGAVFVGSAEGDSWLAKVNVVRQVVERSEKKKDEMEVDWDEDLYGDINDAALDEKAQELFGP
AAITLSPYDILTGVGKIMDIEFGIAASDQGLRTYPQLVAVSGGSRNSTINVFRRGIPITKRRRFNELLNA
EGVWFLPIDRQTGQKFKDIPEAERATILLSSEGNATRVFALFSKPTPQQIGRLDGKTLSAAPFFQRSCIL
RVSPLEVVLLDNNGKIIQTVCPRGDGPKIVNASISDPFVIIRRADDSVTFFVGDTVARTVAEAPIVSEGE
SPVCQAVEVFTDTTGVYRTFEPSKSESSEPISHQIDSENKPNITNGINGTTARSARQTQLTPQQIKRLQE
QEPAITTEAPSMETAINSPHGTQWLALVTRGGELQIRSLPDLQIVLQSEGLASSAPSFTDDLGENPGYVL
GEKREEGEEEDEIIQMVFCPIGKGTVRQHLLALHHSGRLNAYEAQPRFTVDASSHSRRSLAVRFRKVHTQ
LLPISGGVGTTNGNARLPYTIVPFNNIEGLTGAFITGEKPHWIISSEAHPLRAFALKQAAMAFGKTTHLG
GKGEYFIRIEDGSFICYLPPTLNTDFAIPCDRYQMERAYTNITFDPTSAHYVGAASIEVPFQAYDEEGEI
QLGPDGPDLIPPTNQRSTLELFSQGSDPWKVIDGYEFDQNEEVMSMESVNLESPGAPGGYRDFIAVGTGF
NFGEDRATRGNTYIFEILQTVGPQGGGGPGSVPGWKLVKRTKDPARHPVNAVNHINGYLLNTNGPKLYVK
GLDYDSQLMGLAFLDIQLYATTVKVFKNFMLIGDLCKSFWFVSLQEDPYKFTTISKDLQHVSVVTADFLV
HDGQVTFISSDRNGDMRMLDFDPTDPDSLNGERLMLRTEYHAGSAATVSKVIARRKTAEEEFAPQTQIIY
ATADGALTTVVSVKDARFKRLQLVSDQLVRNAQHVAGLNPRAFRTVRNDLLPRPLSKGILDGQLLNQFAL
QPIGRQKEMMRQIGTDAVTVASDLQALGGFW
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CFT1 mutant is attenuated in mice (Jung et al., 2008).
References
Jung et al., 2008: Jung WH, Sham A, Lian T, Singh A, Kosman DJ, Kronstad JW. Iron source preference and regulation of iron uptake in Cryptococcus neoformans. PLoS pathogens. 2008; 4(2); e45. [PubMed: 18282105].