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ccr4

Victor ID 4723
Gene Name ccr4
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans JEC 21
NCBI Gene ID 3254820
NCBI Protein GI 58261188
Locus Tag CNL04550
Genbank Accession AE017352
Protein Accession XP_568004
Taxonomy ID 214684
Chromosome No 12
Gene Starting Position 267807
Gene Ending Position 268943
Gene Strand (Orientation) +
Protein pI 4.44
Protein Weight 31303.12
Protein Length 285
DNA Sequence 
>gi|58271749:267807-268943 Cryptococcus neoformans var. neoformans JEC21 chromosome 12, complete sequence
AATGCCCCAGCAAGAGCAATTACCATCAAAAGACTATGGAATAAGAGAAGTCCGCACCTCCTCCCGCTCG
CTCAGCCAGTCGCTGACAACATGACAGATATGGGCAGACAACCTCGAATCAGAGTTTGCAGCTCTGAGAC
AAGCTGTCGAACGATATCCTTACATTTCCATGGTATGTCCCACAAATTAGCTCAAGATATTCTATAATTG
ATGGTTAACGTGTCTGTAGGATACTGAATTTCCCGGTATTGTCGCGCGTCCAATAGGCAACTTCAAGACC
GGCTCAGATTATCACTTCCAAACTATGCGCTGCAATGTCGATATGCTCAAGATCATCCAACTGGGCATCA
CATTATGTGATGAAAACGGAGATTCGCCAGAGGTTTCAACATGGCAGTTTAATTTCGCGTTTAGCTTGGG
GTGAGTCAGGTTCAGCTTTCAATGGGACGTTCTTTGTCCAAGTCGCGCGCTAACGATATCCTTTATTCTA
AAAGAGAGGACATGTTTGCTCCAGACTCCATCGATTTATTAAAAAGCTCAGGAATCGATTTCAAGCGCAA
CGAGGAAGAAGGAATCGACGTCGAATACTTTGGCGAGCTTCTCATCACATCTGGGCTTGTTCTCTTTGAC
AATATAAAATGGGTGTCTTTCCACTCGTACGCCTTTGAATCCCTTCGTAACTTTCGCGGACATTGCTGAC
TCACATTAGAGGGTACGATTTTGGATATCTTCTCAAGATCCTTACATGTGAACCTCTTCCAGCAGATGAA
ACAGACTTTTTCCGCCTTCTCTTTATTTGGTTCCCTTGTATCTACGACATCAAGCATATTGTGCGGTCCA
TTAAAACTCTTCGAGGGGGATTACAAGAAATTGCAGAGTCACTGGGCGTCAAGAGAATAGGACCTCAGCA
CCAAGCAGGATCAGATTCTCTCTTGACCGCCGCAGTTTTTTTCAGGATCCAAACGATCTACTTTGACGGA
CACCTGAATGATGATTACTACAAGTGAGCTCATTTATTTATGTCATGGTGATATTGCTGACCCCATCTAG
AAATTACTTGTACGGGTTTTCTTCAGGCCGTTTAGGCAAAGCATCTCCGGCAGCTGCTGGCGAAAATCTC
GTTGACAAACCCTATTA
Protein Sequence 
>gi|58261188|ref|XP_568004.1| ccr4-not transcription complex, subunit 7 [Cryptococcus neoformans var. neoformans JEC21]
MPQQEQLPSKDYGIREIWADNLESEFAALRQAVERYPYISMDTEFPGIVARPIGNFKTGSDYHFQTMRCN
VDMLKIIQLGITLCDENGDSPEVSTWQFNFAFSLGEDMFAPDSIDLLKSSGIDFKRNEEEGIDVEYFGEL
LITSGLVLFDNIKWVSFHSGYDFGYLLKILTCEPLPADETDFFRLLFIWFPCIYDIKHIVRSIKTLRGGL
QEIAESLGVKRIGPQHQAGSDSLLTAAVFFRIQTIYFDGHLNDDYYKNYLYGFSSGRLGKASPAAAGENL
VDKPY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ccr4 mutant is attenuated in mice (Panepinto et al., 2007).
References
Panepinto et al., 2007: Panepinto JC, Komperda KW, Hacham M, Shin S, Liu X, Williamson PR. Binding of serum mannan binding lectin to a cell integrity-defective Cryptococcus neoformans ccr4Delta mutant. Infection and immunity. 2007; 75(10); 4769-4779. [PubMed: 17646356].