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apt1

Victor ID 4716
Gene Name apt1
Sequence Strain (Species/Organism) Cryptococcus neoformans var. neoformans JEC 21
NCBI Gene ID 3257282
NCBI Protein GI 58266214
Locus Tag CND02400
Genbank Accession AE017344
Protein Accession XP_570263
Taxonomy ID 214684
Chromosome No 4
Gene Starting Position 636712
Gene Ending Position 646781
Gene Strand (Orientation) +
Protein pI 9.43
Protein Weight 321417.73
Protein Length 3012
Protein Note Supported by
DNA Sequence 
>gi|58272421:636712-646781 Cryptococcus neoformans var. neoformans JEC21 chromosome 4, complete sequence
AATGCTCTTCCTCCCATCCTTTACAGCCATATCCGTCACCTTGCTTATTCTAGTCCTCTCCTCTTTGGTC
GTCCACCTGCACATCCTCCCACTACTTTTGCGCACATTCACTCAAGTCAGAGTATCGAGCTTTAGCGTTA
TATCCATTACAGGTCTGGAATGGCGAAATGAACATGAGCAAGAGGATATAATCCCTACATTGAGAATAGA
GAGAGCCAGGTGGACGTGGGGTGGCATCAAAGGAGACGTGACCGGGCTTGTTGTGCTTAGAATTGAAGGG
GTCAGTTGGAGAATCAAGAACAATCCATCGGGAGATCTGAAAAATGGAAGGCCGTCCGTACAGCATAGAG
TCAGTGACCGTTTCATTTCAGCCGCAGCCGATCACACGACTAAATATATTGACGCCGAAAAACCAATAGT
CTCCAAGCCGCTTCAAGAACAGGCTTATCACCTTTATTCTCCGACTGCTCATTCACCACTATCCTTCGAT
TGCTCGACTCGTCTCCATCCAACTTGTCAATTGCAGGGTTATCTTTGATGACTTGGATGGCATCGAATTA
ACTTGGAAAGAGCTGGGGTTTGGCGTCAAGGTCGAGTTCCGTGGTATGGCCGAAGAAGCAGCTGTCTCAA
CCGCTCCCGAAAGGGAAGCCCCTTTTCGATCCTTATCTTCTATCAGCTTTAAAGATGAGTATGACATCCC
GCCTTCATTTCCAACCACAGCAATGTCGACGCCGTCTCGACACACACAGTCTCTCTCCGGCTCACCGGTC
ATGCACACATCATTTGCCTTGCCTCCTTTGGCTGAACCTTGTGAGGCTTCTCTCCCTCCTTCGCCTGGCA
AGAAGGCGCAGACAACCCCCCGTTTATCCAGCCCGAAGCCCTTCCACTCTCGAATGTCCAGAACAGCGAA
CAAGATTTGGACTCGTGCCACAGGCCGAATGTACGGCTCCGTTTCTTTCAACATCTACATCGATACTATT
CGGTGTATCGACCCTCGGAACAGCCCACCTCCGTCTGCTAAGCCTTCCATACCCGACCTCAAATCGTCCA
CCGCTCGTAGGTCACAGTTCATCTCCTTCCGGCCTCTTAAGCGATGCCATCCTGTCTATGATCTCCATTC
ATCAGATGCAGGGGTGAGCACTCTAGTGGCATTAGATGAAAGGTCTAGTGTGAGACTTAGCCTTGGATTT
GGTCCCAAAAAAGGGTTATTGGGCGAGGACACTCTGAGCGCGGTATATGAGATGGGCAAACTGCGCACGA
CTATAGAGGCCGTCGAGAAAGCAAATAAATTGCTCAACAAATCGAAGAAAAATAAGCAAATGGAGAAGAA
GGGTATGAATCGATGGTCAACGCATGGGACTGCTCGTGTACGTTTATTCCTTACACAAAGGTTAGCCGGA
CGACACTGACAGTAGCTATCAGGTCATCTTAAGAGCCATGCAGTCGACAAAAGTGTCATTCGCCCATATC
ACTCTTCTTCACCACCTTCACAATCCTTCTCCAATTATGCCTTCCCTGTCCCAGTCTCACTTATCATCCA
TCTCATCCCTTGATCTGTCATCTTCACCAACGGGGGACCGTTACACAATCATTCTCGAGCTTTCTGAGAT
AAGATGTGCTCTCTCATCGGCCGATTCATCTAACAATGACCGCGCTCGCAACGCCTTTGGTACCAATTCT
AGTCCCGAGTCCATCATCCGTGGTGTGGGTGCAGAGTTTGGGTGGAAAAGTATTGAGCTCCAGTGTATTG
CGCCTGGCGAAAGCTCAAATGACAAGTCGCAGTTGTTTGCAATTCGGCAAGCGCAAGTGATTGGTTTCTC
GTCATGGCGACCTGAAGGGTGGAATAGGGAGGAACTATTATTCGCCAGTGACCCAAACATTGCCCTTGTA
GTCTGCCAAGCCGATGTTGCAAGTGTGGATTGCGCGGGCGATCTGCAGTTATTACACGAGCTTGAAGCGG
CTTGGAAGGCCACTTATCCCAAAAGTCCTACCAGTTCGCCTCCACCGTCGTCCGAATCACCTATTATCTC
ACACGAAGACCCGTCTGGCTGGTTGCCCCCCAGGCTTCGAATGGTTTTCGATGTGGGCGATATCATGGCA
GTCCTTGCGGATAGGGTGTCAGAGAACACAACCACGCTCACATTCGCCCTTGCTGGCGTCCATTCCAGTT
GTTACACCTCTTTCTCAGATATCATCGCCCGTCGCCGGGACAGAGTGGCTACCAAAGAAGCTTTTAAAGA
AGAGGAAGAACTGCAGCAAAGGAGAGAAGAGAATGACGAATTGGACTTCGCCGTGCACCCTTCTATGCTG
CCAGCAGCACTGCGCCGACGATCGACGGCCAACAAGGCAGAACTCAGGGATAATCTGTCCATTTCCATGA
GATGCGATGCCACCGTAAAAATGGAGCCCATCAGAGTCAAGATGACACTTTCAGGAGACAAAGTGTATGA
GCTCGCAGAAATTGGAAGGATATACGGCACAGTCACAGGGGATATACTTGGGAGGCTTAAGGTTAAGCCG
GACGGGACAGAATCGTCATCTTTTGACTGGAGTTCCATTTCCTGTGGATTGGATGTGGGTATACAGGAAG
GAATAGACGTGGATTTATGGAAAGAGGAAGTTGTGGAGGCTCTCATAGGTATGGGAGAGGCGCATCAAAG
AAGGCCCAAAGATGATCGTCAGCCTTCGCCAAGTGAGGGGAAAAAGACCACCACTATCCTCGACAAGCTA
CCTTCGGGAATATCAGCCAGGCTTTCACTGGGCAAAGTCAACGTTTTCTTAGGTGTTAGGGATCCAAACC
CCGAATGTGCATTGGGTCTGACCAGAGGATTATGGTTCCGGACAGTGTTGAAATTGGAATATGCGTATCA
CAAAACCGTCATCCAATCTCTCCCTTGGCGCCATACACTGACCACCCCCCGCCGAGCCAAGCTACGACTT
CCCGAAGATATCACCACGCAATCTCTTGCATTTGGGGCCAAGCTTCGTTCTACAGGGGGTAGTGCAGCGT
TGGTTTCCATCAACACCGAGGAAACATACTTCCAGCCTATCTACAACGGCGAAATGTTCATCAAAAAAGG
CGGGTTCAAAAAGGGCGTTTTGCGAAAAGACCCCCCAAAGGCGAGAGAAGACGATGAATTTGTTGGTTGG
GGATTTCAACGAGCTAAACAACTTCGAGCAATGGATGAGGGCAAGTTTGCGAATAACGTGCCCCCATTTG
AGATGAGAGGCACAGAGCAAGCGCGGAGACCATGGCTAAGGATTCCACGATCACATACTTCTTTTGCGGC
TCAGCAACCAGCACCCGGTAGCGATATTGAGTACAAAATTACCACTCGGATGGAATCACCTACCTTGATT
TCCGATCTATCCCATATATATTGCCATCTTCTCGCTGGTTTGATGGTCAAGCGAGTAAGCGCAGCTTGGA
GGTCGGGGTCGGGTAAATCTCAGGTCACTCAGTCCGCCTTGCCCAGCAATAATCTCAACCTTAGTATTGA
CGTTTCAATCCCCGGCATGACCGCTCACTTCGCATTTCCTCTTCAAGAACAGCTCTTCATGTATAGCTCC
GGTATTACTTTCAGCAAACAGCCTTACAAAGGCATGGTGTTCACAGCTGAACAACTGCTGTTATACGTTC
CTAGTCCCCGGATCATCGGTAGCTGGGAAGAGCTCGGTCGTATCAAGCAGTTCGCACTCGCCCTCTCGGA
CCCTCACTTGCCGCTTGTCATTTCCCCCCGAATAGAATCTTTTCGTGTTCGTATCCCATTTTCTTACAAG
TTGAACAGCCTCATCCTCAACATCAATGTGACCGTCAAAGCCTGCAAGCTCCTTTTCCGAACGGTCTCAG
GCAAAATTCCCTTTACCACCGTCTTCAAGCCGTGCGCAGAGCAACCTAAGAATGTTCCAACCTTCTCGTT
CAGCGTTGGATATATATCACTTGAGATAAAAGACGACCCTGTAGAAACAAGCCTTAACCTCATTTGGAGA
GCGGGTCTGGTAGAACAAGCTAAGAGAAACGCTCTAGAAGACAATTTTGCAAAGAAGCTGTTGCTTATTA
GCGACCCCGACACTCAACCAGAGGTACAGGAGGATACGAGAACTGGAAGTGGGCGACGGATGCTTGTCCT
CACTAAGAAGCATAGCGTTGGTCCTGAAAGAGCCAGATGGGCGCTCGATCTGCTAGTATCTCAGTCATGG
ATCAGGCGTATTCGGGCTGCCAAACATGAGCAGGCCAGAAGGGAAGTATTGGCTCTTCAGGCAATTAGTG
GGTCTGGTGTCAACATCAAGCTTCCGATTCGAGTAGTCAGTTCGAGCCGCACAGCTCCCCTCTTTCGAGC
AGCATTTCATGAGGTCAACCTTGTGATCACAAAGCCAGGCCTTGACCGGAAGCAGATCATTGATTACATG
GGCAAGATGTCTGCTCCATTTTCTGATGATGTCAACTTCTCCCTCATGGTTCCCCTTAACATTCGGTGGT
CCATGGCGGAGGCGAAGTGTACCCTTCGAGACTATCCTCTTCCTCTTATCCGAGTGCAACGAGTCAATAA
AAATGAACAAAAACCGGCCTTTTACATGGAGACAACTATGGTTATTGCGGAGGAACTCGCTGACGATGAT
TCAGTCATGTATGTTCCGGTCAAGGTTATACCAGAAGGATGCGGCCACAACGGTGCTTCCCCGTTTGTCC
TGGAAATTGCAAAAACGATTATGCCAGTCAAGACATATGCTGAGCCGAAATTCAAGATCTCTTCAAAGAA
GACGACGGAGTTTACCTGGGGAAATTCTTATCAGCCTGCTATCCAAGATCTGATGAAAGTCATAGAAACT
CTGTCTCATCCCCCCCGGGATCCTTCGCCAAGGGTTGGATTTTGGGACAAATTTCGACTTGTACTTCACT
GGAAACCTATTGTGGATTTTGTAGGGCCGTGTCATCTTCATCTCAAGGGTAAGCTTAAGCTCCGTAAGAT
ATTTCACCAGTATCTGGTTGTTGATCCCAATTAGGCTCCTTTGATCCGTATTCCGTCTCCGGACTCGGTT
CTGGCTTTTGTCTGGCATGGCGTGGCAATACTCAGTTGTTGATTGACCAGCCGAACGCGGATAAGGAGGC
TATTCAAATTCTGGCTGACGAGCTCGTCGTAGCTATCCCAGAGTAAGTACAAAGATTGATCAGCTTGCCT
AGTACTGACATTATCTAGTTTGGCGCCATTCCACGACGGGGCAGCAATCGGCAATAATCGAAATCATCGA
CATGATCATCATGATCATGCTCGAGAGCGTGACATCCTGGACGATACTGATGTAGTGCCCCTCGAAAGAC
GTTACACCAAACCTTGCGCCCAATTTGTTGGGGGGGTGAGGGTTGGGTTTGGTTTTAAGCTTGAAAGGAC
TTGCCGGCCCTGGTCTTGTCAACATGGATGTGGTGACACGGAGAATCTCCTCCACAGACAATGTCGGGAA
TTTACTTTTCTGCAACATCAGCAAGTCATTCTTCGCTCACCAGAAGCGATTGCCAAGGCAGAGAAAAGGT
TGGGCAGAGTAAGTTTCTGAGGTCGATCTGTATGCACAAGAACTCATGGGTCTTCCACAGAAAGTAGACT
CTTATGAAGGCTTCCGAAGCGACTTCATTCACTTTTCCGTCTCTCTTGTAGCGCCCAATGGAAATGGATC
CGCCCACAGGACGCAAGAAGAGACGCCAGACAGCGTCAATAGTCTTCATTTTGCTCCCAAAGCATCACAT
CACTTCTTGAGCTGGTGGAAGTGAGTATTTTTTGGCTCTTTTTTATCTTCGTTGCCCCTTCCTGGGAGGC
GCTTACAGTAGGCCAGACTTTTCTCCCACCAGATGTCATTACCTATCCGTCATGGCAAATTATTCCCCGA
TTCTCCACCGCCATCCAAGAAGTTCGGTCGCAGTCTTGGCACTATAAAAGTAGGTTCTTTCTGTGCATTT
GCTTTGCTAATGAATGTAGTATCGATTTGATCTACGACCAGTATACATCTCCCATATGTACTCCCAAGTG
AGCAAGGATCATTCGACTACCGGCAAATCTGAGTCCCTCGGTATCAAAGCTCGTTTTGGCCGGTTCAGAG
CGGATGCGCATCAGCGTGCGCAGGAGAAGATTGAGCGGCACGAAAAGCTTGGGCGGTCTACTGTCGTTGT
GCACAAACCTTTCTACGCTGGGGACATCCTTGCTGATGACCTCAAGGTCAAAGGCGTGCGAGCTCATTTT
GTGGAGCGTATCAAAGGTGATAATACCCCGCCATCCGATCCTCTTCCGCGAGCTTCAGCACTCCCGCCTG
AAACCCGACATTGGTATAACTATTGTGACTTCATTGATGTAGACCGCAAACCAAGTGATAAGGACCCTCG
CATAGAACTAGCTGATTTCGGTGACTGTCCTCACCTCTTTTACTGCAAACGAGTCAAGGCCAGGGCTAGT
ACTTCCCATGATGACTCAGGTAGCCAAGCAAGTAGTTCTCTTGGTGTAGAAAGTAGTAAATTCGGTCACG
AAGCTACTCATCACTGTTACCTTGGGATGGCAGATTGTGTACGGGACGCACAGCGTTCGATCACCCAGAA
GAGGATCAATGAATTGCAGGCCAGGCTAGATAGTTACCCTCCCCCTCAAGATGACGAGAATCAAGTGAGT
TCCCATTGTTTCTTGAATGATTTTATGAGTAATCAGATGCTTACCTTTTGACATAGTCGGACCGAGCAGT
AACTCTAAATAGGATCAACGTCTTAGTCAAGCATTACGAGGATCTTGAAAAAGAGACTCGCCATCTCAGT
GATGAAACCCTGGAATACTCAAAACAAACCACCACTACTACGTTTGAGCGGCCACTTTCCGGTGCTGCCT
TTCAGGATATGATACACATACATGGGCCTAGACTAGTTTTAACAGATGGGTCAAGGAACATTGGGTTCAA
ATATCTATATATGATGGGGGACAGGAAAAAGGAAGAATACTACACATCTTACGCGTAAGTCGAACTACTC
GCAGCCATGACGCATAGCAAACTGACATCCGAAGTAGATCTTTGCGCGGCATTCTTGACACTTATCAGCA
GCGTGTGCGCCGGCGTGCGCGGCCTGAGACTGAGGTTTTCGAGGATGAACAAACCAAAAACACTTCGGCA
GATCAGCAAATGGTGAATGACCTGATCCGATGGCTCTCTGACAAACCCGCGTTGGACAGTCTCCATACGG
ACGATAATGCCGAGGAGGGGTCTCTCCGAGCACATCGCGGATTGCCCGACGATTGTGATGTTAAGCCCAA
CAGACATGTGCTTGTTTTCAAACCGCAGATTGCGCTTCGCAGCGAATCCGATCCGAACGCCATCGTGCTT
CTTTCCGCGGAGGAATTCTCCTTCAAACAGTTTAAAGTCATCGATTCTAACGCCATTGATGATATGATGG
CAGATGTGCTTGACAGGTAGGTTCCCTCAAAATGGCTTATACTGATGCTGCAGGAATTACATTTCAATGC
AAGGTTTGCAGGGTTTCTATCCAACTACAGAGGCTCTCAAGAGGGAGCGGACACAGCTCGGCATGCCTCG
TGGCCTCGACTTCATACCACTGGAAATCTTTTTGGACGTGAAGAGTGAGGCTACAGATTACGACCGTGTC
CTGCAAAAATCCGATATCATGGTTTCCATCGACAAGTTCAACAATATCCGTATGCCTCGCGGCTTAGAAT
GGCCGGATACTTTGGATGAATATGGAGAGCCTATCAAGCACCTTAGAGTTCATCAGGTTAGTGTCTTAAC
GTGTCGGAATAAACAAGGTTTTATTGATCATATTTATGATATGCTAGGATTATACTGCTATAATTGCTCC
CATGCTTACCGTGACCGCCAATTCCCGCAATTTTGAGGCATTGTATGTCATCGTAACGGATCTGCTGATG
TACGAAGATCCCGGGCATAAAGACCGCTCGGAAGCTATAGACGATTTTACTCGCACATTTGATGCAGCAG
ACCGAGACCTCGGAAAATTAGTCACAGACATCAACGCCTTGCAAACGCACATGCGTGGCCTTCTTGAGCT
GCAGCACGGCTACGAATCGAATTTCGAGAGGCTTAACGACACTGGAAAGGAAGAACTTTTCAAGATACGA
TCTGAGCTGCAAGTTGGGTATGAAAACATGTACACAATCAACGCCCTAATTCGAGCTACGTCTGCGAAAG
ACGATGCGCGAGCTGCTATGAAGACATCAACGAAAATGGATGTGCGAATTGGAGGTGTAGCGTGGCATAT
GCTGCGAGAATCGAGGCTTGAAACTATGGCGAAGGTTGACATCAACGGTGCCGTATTTTCTATGTTAACC
AGTAAGAACGGCATAATGGACAACGCAATGGTAATTGGCGATTTGAAGGCTCTCAATGGCAAGTGGAACA
CGCTGTATCCAGAGATCATCATTCGAGATGATCCAAGCAAAAAGAAAATAGTAAGTATATCTGATACAAT
GAAATTGTCACTGACGATACTGGTCACAGAAGAAGCCATTCGCTGCAGTTTATTGGTCCACTCGCCCCTC
GATCGGCGGTATTCCTATTTTCCCTTATGTGAATATTGAATTCGTCAACATCCGCTTCAAGCTGGAGGAG
AGGGTTGGGTTAGATGTTATGGATTATCTCTTCACTGACAGAACCCGTCGCCGTCAAATATCCGGTACCG
CTGTCAAACCGCCTGGTGGAAATGGTGCAAGTTCCACTACTCCAACCTCATCCATCTTTCGCGGGGCAGG
AATGACTTCCATGGACGATCTAGGCGGTAAACGGGGCGAGCCTCTTGGTATAGAGAATGGTCCTTTGCCA
CGATCAAGGTCACAGGTTTCGCTTCTCTCTCTACCCCAATCCGACCGTGACCCTGTATCGATTAAGAGAA
TTGAGGACACCAAGGAGATGAGACTGCGCGCATCGACAAACAAGATGTTCGGGACATTTAGATTACAGGG
AATGGGCTTCAACCTAAGCTACAAAGTAAGTAATTTATCAGGTTGTGCTTAAACCATTGCTCTAACTCTG
TCTTTAGAGTGATGATACTCGGAAACATGGCACCTTTAGCATGCCAGATTGTGTTGACTTTAGATTCAAA
ACGCCAGAGATGGTCTATGTCAGCAAGGTGTGGAGCATGGAGGATCTTTTTGAACACATCAAGCGAGGTG
AGCTACACACGGTCTTCGTTCTTCATTGTAAAATACTGAGTCAGCATGCTGACTCTTTGCCTTCAGATGT
TAAGAGTTCGGCTTGGTCCCAGTCAGGTGATATCATCTCACAAATCTTCAAAAAGACAAGCCTCTTCAGG
TCAAAAGAGCGTCTTAAGCAGGCTGCATCAGTCACCGCTTTGGCAGAAAAAGCTCACAAGGGCAAAGGTT
CTCATCAGCACCCTCCTAAATCGCCTTCGAATCTCCGATATGCCTTCAAGAACTCTAGTAATTCTCCCGA
ACCCGACGAAGACCTTATCCGGACAATCTCTCGAGTTATGTCTCATGAAGCAGTTCCGCCAGAAGAAAAA
CGAAGGTCCAAATCTGTACATCGTGGTTACTCCAACAATTTGGACATTCGGTCTGAGCCTTCAGAAGGGA
GTAGCCAGCGACACGCCCATTTACGATCCACGAATGATCACTCGCCTAACAGCGGAAAGAGGTCCGTGGA
AGAAGTGCCAGAGACAGAGGAGAAAGGAGGAGGGAGGATCAAGGGGCTATTGGGGAAGCTCAAATCCAAG
CATCTAGTTGGAAAAGATAAGGAGCCAAGGTCCAGTGAGGATGTGAGTCAAACTCCTATTGAATAATATC
ATAATCCCCAGCTGACTGACAGAGGAAGTCTTCCGGGTCGTCATTGAGAAAGTCAACCATATGAAGATGC
TGCTCATTCATTACAACACTGACCTAACCCGCGGTAATTTGTAGTTTTTGGCTTACCGTCTCTGTATCTT
TCTCTACCTTTTTGGGCTCTTTATATCTGCTGTTCTTTAATTGTATAGGAGTTTCAATAGATAATGCCAG
TTATTACTATCTACACTTCTTCCTTTCGCCAAACTGCATGCTACAACATACATTTGTCCA
Protein Sequence 
>gi|58266214|ref|XP_570263.1| hypothetical protein CND02400 [Cryptococcus neoformans var. neoformans JEC21]
MLFLPSFTAISVTLLILVLSSLVVHLHILPLLLRTFTQVRVSSFSVISITGLEWRNEHEQEDIIPTLRIE
RARWTWGGIKGDVTGLVVLRIEGVSWRIKNNPSGDLKNGRPSVQHRSPSRFKNRLITFILRLLIHHYPSI
ARLVSIQLVNCRVIFDDLDGIELTWKELGFGVKVEFRGMAEEAAVSTAPEREAPFRSLSSISFKDEYDIP
PSFPTTAMSTPSRHTQSLSGSPVMHTSFALPPLAEPCEASLPPSPGKKAQTTPRLSSPKPFHSRMSRTAN
KIWTRATGRMYGSVSFNIYIDTIRCIDPRNSPPPSAKPSIPDLKSSTARRSQFISFRPLKRCHPVYDLHS
SDAGVSTLVALDERSSVRLSLGFGPKKGLLGEDTLSAVYEMGKLRTTIEAVEKANKLLNKSKKNKQMEKK
GMNRWSTHGTARVILRAMQSTKVSFAHITLLHHLHNPSPIMPSLSQSHLSSISSLDLSSSPTGDRYTIIL
ELSEIRCALSSADSSNNDRARNAFGTNSSPESIIRGVGAEFGWKSIELQCIAPGESSNDKSQLFAIRQAQ
VIGFSSWRPEGWNREELLFASDPNIALVVCQADVASVDCAGDLQLLHELEAAWKATYPKSPTSSPPPSSE
SPIISHEDPSGWLPPRLRMVFDVGDIMAVLADRVSENTTTLTFALAGVHSSCYTSFSDIIARRRDRVATK
EAFKEEEELQQRREENDELDFAVHPSMLPAALRRRSTANKAELRDNLSISMRCDATVKMEPIRVKMTLSG
DKVYELAEIGRIYGTVTGDILGRLKVKPDGTESSSFDWSSISCGLDVGIQEGIDVDLWKEEVVEALIGMG
EAHQRRPKDDRQPSPSEGKKTTTILDKLPSGISARLSLGKVNVFLGVRDPNPECALGLTRGLWFRTVLKL
EYAYHKTVIQSLPWRHTLTTPRRAKLRLPEDITTQSLAFGAKLRSTGGSAALVSINTEETYFQPIYNGEM
FIKKGGFKKGVLRKDPPKAREDDEFVGWGFQRAKQLRAMDEGKFANNVPPFEMRGTEQARRPWLRIPRSH
TSFAAQQPAPGSDIEYKITTRMESPTLISDLSHIYCHLLAGLMVKRVSAAWRSGSGKSQVTQSALPSNNL
NLSIDVSIPGMTAHFAFPLQEQLFMYSSGITFSKQPYKGMVFTAEQLLLYVPSPRIIGSWEELGRIKQFA
LALSDPHLPLVISPRIESFRVRIPFSYKLNSLILNINVTVKACKLLFRTVSGKIPFTTVFKPCAEQPKNV
PTFSFSVGYISLEIKDDPVETSLNLIWRAGLVEQAKRNALEDNFAKKLLLISDPDTQPEVQEDTRTGSGR
RMLVLTKKHSVGPERARWALDLLVSQSWIRRIRAAKHEQARREVLALQAISGSGVNIKLPIRVVSSSRTA
PLFRAAFHEVNLVITKPGLDRKQIIDYMGKMSAPFSDDVNFSLMVPLNIRWSMAEAKCTLRDYPLPLIRV
QRVNKNEQKPAFYMETTMVIAEELADDDSVMYVPVKVIPEGCGHNGASPFVLEIAKTIMPVKTYAEPKFK
ISSKKTTEFTWGNSYQPAIQDLMKVIETLSHPPRDPSPRVGFWDKFRLVLHWKPIVDFVGPCHLHLKGSF
DPYSVSGLGSGFCLAWRGNTQLLIDQPNADKEAIQILADELVVAIPDLAPFHDGAAIGNNRNHRHDHHDH
ARERDILDDTDVVPLERRYTKPCAQFVGGVRVGFGFKLERTCRPWSCQHGCGDTENLLHRQCREFTFLQH
QQVILRSPEAIAKAEKRLGRKVDSYEGFRSDFIHFSVSLVAPNGNGSAHRTQEETPDSVNSLHFAPKASH
HFLSWWKLFSHQMSLPIRHGKLFPDSPPPSKKFGRSLGTIKYRFDLRPVYISHMYSQVSKDHSTTGKSES
LGIKARFGRFRADAHQRAQEKIERHEKLGRSTVVVHKPFYAGDILADDLKVKGVRAHFVERIKGDNTPPS
DPLPRASALPPETRHWYNYCDFIDVDRKPSDKDPRIELADFGDCPHLFYCKRVKARASTSHDDSGSQASS
SLGVESSKFGHEATHHCYLGMADCVRDAQRSITQKRINELQARLDSYPPPQDDENQSDRAVTLNRINVLV
KHYEDLEKETRHLSDETLEYSKQTTTTTFERPLSGAAFQDMIHIHGPRLVLTDGSRNIGFKYLYMMGDRK
KEEYYTSYASLRGILDTYQQRVRRRARPETEVFEDEQTKNTSADQQMVNDLIRWLSDKPALDSLHTDDNA
EEGSLRAHRGLPDDCDVKPNRHVLVFKPQIALRSESDPNAIVLLSAEEFSFKQFKVIDSNAIDDMMADVL
DRNYISMQGLQGFYPTTEALKRERTQLGMPRGLDFIPLEIFLDVKSEATDYDRVLQKSDIMVSIDKFNNI
RMPRGLEWPDTLDEYGEPIKHLRVHQDYTAIIAPMLTVTANSRNFEALYVIVTDLLMYEDPGHKDRSEAI
DDFTRTFDAADRDLGKLVTDINALQTHMRGLLELQHGYESNFERLNDTGKEELFKIRSELQVGYENMYTI
NALIRATSAKDDARAAMKTSTKMDVRIGGVAWHMLRESRLETMAKVDINGAVFSMLTSKNGIMDNAMVIG
DLKALNGKWNTLYPEIIIRDDPSKKKIKKPFAAVYWSTRPSIGGIPIFPYVNIEFVNIRFKLEERVGLDV
MDYLFTDRTRRRQISGTAVKPPGGNGASSTTPTSSIFRGAGMTSMDDLGGKRGEPLGIENGPLPRSRSQV
SLLSLPQSDRDPVSIKRIEDTKEMRLRASTNKMFGTFRLQGMGFNLSYKSDDTRKHGTFSMPDCVDFRFK
TPEMVYVSKVWSMEDLFEHIKRDVKSSAWSQSGDIISQIFKKTSLFRSKERLKQAASVTALAEKAHKGKG
SHQHPPKSPSNLRYAFKNSSNSPEPDEDLIRTISRVMSHEAVPPEEKRRSKSVHRGYSNNLDIRSEPSEG
SSQRHAHLRSTNDHSPNSGKRSVEEVPETEEKGGGRIKGLLGKLKSKHLVGKDKEPRSSEDSSGSSLRKS
TI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: apt1 mutant is attenuated in mouse inhalation model of cryptococcosis (Hu and Kronstad, 2010).
References
Hu and Kronstad, 2010: Hu G, Kronstad JW. A putative P-type ATPase, Apt1, is involved in stress tolerance and virulence in Cryptococcus neoformans. Eukaryotic cell. 2010; 9(1); 74-83. [PubMed: 19949048].