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STE11

Victor ID 4706
Gene Name STE11
Sequence Strain (Species/Organism) Candida glabrata
NCBI Nucleotide GI 51235725
NCBI Protein GI 51235726
Protein Accession AAT98628.1
Taxonomy ID 5478
Gene Strand (Orientation) ?
Protein Name protein kinase MAPKKK
Protein Note Ste11
DNA Sequence 
>gi|51235725|gb|AY603493.1| Candida glabrata protein kinase MAPKKK (STE11) gene, complete cds
GGGTTATCCTTCTTCTGCCATGTCAAGTATAATCAGTACTTTTTCTTGCCCGCCAGCAGGTGTCGCCAAT
TAGCAGGCTTATGCTACGCTCCTAGTATCTTATTGCTAGGGTTATGAACCTCATATATTCTATACAATTT
TTTAAACATTATTGACCACATAGGGAGGATGAACTTGACATGTTACAGCTCAAGGATCTGATCTTGACAG
AGAAAATTATTTTTTAACGTGCCGGTTACTTCAGTACATTAGTCTCATCAACTAGCCAAAATACCTGCAC
TGCTAGCAGTTTTAAAATGAAATACTGGCGTACATACAAACCATTAAAGGGCAATATGACACTAATACAA
CACAATACACTCACATGATATTGCCAGCAATTATTGTAGATATACTAGCTACGACCAGAATTGGCTCGAG
GCCTGGTTTTACCTTTCTTAGAAATGCGCAATTGATTACTTGCAGTATTTAGTTGCCTGGTCTGTGTCCA
TCATTTTGCAGCAACCCGCCTGCATTGCCATTATTGGATTCCTTACCATGAACGTCTTTTGTTGTCTGCT
GGTTTGGAATCCGCTGTGGGATCACTCTATGAGGGTTTCTGAACTTCTCTATGTCATATTCAACTTTCTT
GCCACCCCTATCAAGTGTAACCTTAATGGGCTTATCTTCCTTACCGTCACTCATACTTGGTTCTATAGTT
AATCTCAAGGTTTATATTAAACAACCGATTTGATCTTAAGTATGGATATAACTATGGAAATAGGAATATA
AATCAGTTGATATCCTGGGGCTATTTATAGCTGTTTTAAGAAGTGGGCTTTGCCTTTACTATACATCATC
TCGTACTCATCGAATGTGAATTTTGGCATTCCGAAGACATGATTCTTCAGTAATAGTAAAAGTAATAGTG
TTAAGGTACTGGATGAGTAGTACTGATTATATTAGGAACAATCTTTACCACTACACTATACTACTCAAAT
ACTACAATCTTCATTATAATCTATTAACTGAGGAGTGTTATATCTCATGTCCCATATTGAGTTTTTAGAA
AGAGCAGGCTGCTCTCAATATGCAGACTTGTTTGAAGAATACAGCTTGACTGACATCAATGACCTCATGC
ACATAGATCGAGATATTTTGCTCGAGATTGGGGTCAAGAAGCTTGGTGATAGGATCAGAATCCTAAAGGA
ATCAAAGAAACTGCAAGAACCAAAAGATGATGCGAAGCATGTTCAACAACTGCAAGAGCTAATTTCGAAT
ATTAGTGAACTGTCCACTACCAGTACCAATATTAATGAAGAAGTCATAACAGAGAGGCATTGTGTTATAT
TTATATTAAATGATGGGTCAGCCAAGAAGGTTAATATTAGTGGATGCTTCAATGCAGACTCTATAAAGAA
GCGTTTGATTAAAAGGCTACCTTCTAATCTTCTGGCTGTTAATACAGATGGGCAAACTACTCAAGAATCC
TCCGACTATGATGTTTTTATCGTTGACTATTCAAAGAACGTGCTGAGATTACTCTATGATATTGAACTAG
TTACAATTTGCCATTCCAATGACCGTGTAGAGAAGAACAGGCTGATATTTGTGTCAAAGGATCAGACTCC
GACTGATAGAGCGATCAATGCATCAAAGAAATTATATCTGAAAACTATAACAGCACTCAATCATATTGAA
TCCTATTATGATGCACAATCTGGCATGCCAAACACCCCAGTTACTCAGGATGGTACATTAAGGATACATA
AGGAAGGTAAGGATAAACTACGGAAAATATTTGACCAAAGACCTCCTAGTGAGTTTATATCCACAAATAT
TGCAGGATATTTCCCACATGCGGATACAAAGAGGTTAGAAAAGGCCCTGAGAGAGTCCTACCGTCAATCT
GCTAGAATAAGTATGAAAAGCAACAACTCTAGACACATCAGTTCAGAATCAAATCGTGTCGGTGACATTC
TATTAAAGCACTCCAATGCGGTTGACATGGCTCTACTACAAAGCTTGGACAACAACAATGCACCATCATC
TAAACCTGAAGTAATACCACCATCCACACCACAAGAGGAGGATAATGAAGGTAAGATTAAATTAATGGAA
GAGACAGAGAGTATAGACGATTATTATATGAATTCTGATGAAGAGCACGGTACAGTTTCTTTACCTACAA
AGATAGTTACTCCAAAAAACTGGCTCAAAGGTGCAAGAATAGGTTCTGGTAGTTTTGGGACAGTATATCT
TGGTATGAATGCACAGACTGGTGAGTTAATGGCCGTTAAGCAAGTCGAGATTAAGCCAGCTATTGCAGCT
ACAGCAGATGCAAATGTTGAAGATAAGAATGCAGAGAAAAATGTTGCAAAGGCACCTTCAACTAACTTGC
ATCGGAAAATGATTGATGCGTTACAGCACGAGATGAGTTTGTTGAAAGAACTGCAGCATGAAAATATAGT
AACATATTATGGGTCATCTCAAGAAGGTGGCAACCTGAATATTTTCTTGGAATATGTTCCTGGTGGTTCT
GTTTCATCAATGCTAAGCAATTACGGGCCCTTTGAGGAGCCGTTGATTGTCAATTTTACAAGGCAAATAC
TAATTGGTGTTGCCTACTTGCATAGGAAAAATATCATACATCGTGACATCAAGGGTGCCAATATTCTGAT
TGATATCAAGGGTTGTGTCAAGATCACAGATTTTGGTATCTCCAAGAAACTTTCACCACTAAACCAGGAG
AATCAAGATAAGAGGACCTCTTTGCAAGGGTCTGTGTATTGGATGTCTCCAGAAGTTGTAAAACAAACTG
CTACTACTTCAAAAGCTGATATATGGTCAACGGGATGTGTTGTAATTGAGATGTTTACTGGAAAGCACCC
ATATCCAGATTTCTCACAGATGCAGGCATTATTCAAGATAGGTACAAATGTAACACCGGAGATACCATCC
TGGGCCTCTCCACAAGGAAGGGATTTTATCAGGAAGACCTTCGAGCTTGATTACCAGAGGAGACCCACTG
CTATCGAACTACTCCAGGAATCTTGGCTCGAGAGTCATATCATATAGGATGAATATATTAACGAGAATGT
ACTATATAAAATAGGCACTTCGATAATCAGAAAATCCGAAGTGGATTGTACACTTCAACAGCTTCCAAGA
GTAGTCTGGATACCTATAAGGATAGCTAAGTTATATAGGGCATAGACACGTGATACATTATCTACTCCTT
GTAGTCTGTTAATCAACAATACTCAGTCATAACGGTAAGAATCTTGTTGCTGTTTAGCAGTTACTAAAAT
AGATGACCTTTACCCCAACAACTGGTGATATTATAAAGTCACTTACACCTGGAAACTTCTCGAGATTTGC
TTGTTATGTTTAATAAAATTTGGAGAGAATTGTAGGAGTGACTTCGATATAAGAATGTGCTAGTAAAATT
GGGGTGTGGTACTCCAACTATACGTAAAGTCCCCTCGATGAACACGAAGTGTTCTATATCAGAAGCATAT
ATATATATATATAAGATATAACTAAGACTTAACTTTTTTTCGGTCTGGTATTTCAAAGTCATGGAATTGG
CGTCAATTGTCTATCTGTTCGGCGTATGATCCAAACATGCCATTGTAATCGGATCAATGGGGTGTATACT
TTAAATCACGTATCGGTCCTAGCCTCCTATCGGTAAGTGTCATTGCAACTGATTATAGAGGAAGTAGCTG
GGTTTTTTTCACTGGGAAATAGATCGGTTTAAAGGATCTTCCTTTGATTCCAACCTCATCTCATCTCATC
GCCTGCCATGAGT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ste11 mutants are attenuated for virulence in mice (Calcagno et al., 2005).
References
Calcagno et al., 2005: Calcagno AM, Bignell E, Rogers TR, Jones MD, Mühlschlegel FA, Haynes K. Candida glabrata Ste11 is involved in adaptation to hypertonic stress, maintenance of wild-type levels of filamentation and plays a role in virulence. Medical mycology : official publication of the International Society for Human and Animal Mycology. 2005; 43(4); 355-364. [PubMed: 16110782].