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crz1

Victor ID 4701
Gene Name crz1
Sequence Strain (Species/Organism) Candida glabrata CBS 138
NCBI Gene ID 2891693
NCBI Protein GI 50294466
Locus Tag CAGL0M06831g
Genbank Accession CR380959
Protein Accession XP_449644
Taxonomy ID 284593
Chromosome No M
Gene Starting Position 695161
Gene Ending Position 697098
Gene Strand (Orientation) ?
Protein pI 4.48
Protein Weight 69779.31
Protein Length 645
DNA Sequence 
>gi|302309917:695161-697098 Candida glabrata CBS 138 chromosome M, complete genome
AATGGGCGATAACGAAGAGGATAGGAGGAAAAAGTTCCTTAATGGATTACAACTGCAGCCGGACCAGGAT
AATATGTTTTTAGACCAGTATCTAGATCAAGCTGCCGAGTTACAAAGACATCTTCAGGGCAACAACAGCA
TGAATGGCGATGTATATGAACAAGATAACAATAACCATAATTTCTCGACCGGGCAGAATATACTGAGTGA
GTCTACATTTTCACCATCCAGCGACATGTCAAATCCAGTATCTAATCTATTCAACTCCAAGTCTATAAAT
TTCTCAGATATGCCCTATGAAATGGGTGTGGGCGAGGAGACACCCAATGACGATAGGGATAGACAAGATA
GCAATCAGAATAATAACAATAATCTCATGAATACACCTACTTTAAAGATTGAATGCTTTGATGAGGACGG
CGTGTTTCTTCCCGGAGATACAACAAATGACCCTTTTACTCAGGATAGTGGACCCAAATATGATAGCTCG
CAAAATATCAACGCTGGTATTGTCAGTGATATGAATAATTTTGAGAATATGGATAGCAATTTTTTGGATT
TTGGCGGAGATAATCAGGTCTCAAAAGAAGATGGGACTTATCTAGACCTTTATGACAATAACCTAAAGAA
TGCAAGCACAGAGAAGATTGCATCTTCAAATAACTTGAGTGTGAGTAGAAATTCCGAGGATAACCTCTCC
AGAGTTTCATCCACATTGAATAGCCCCTTTATGCAGCCTACAGATAGAAGCGTATCGCCTATACTTTCCC
CACCTGTAATGTACCTGGGAGACCATTCCCACACTGATGATAATGATGACGTTGTAAGCATTCTGTCGAA
TAACTCTAATATACTATTACCGGTAAATTCGCATGGTTACAAGTACGTGACTGACTTCAATCAGCTAGGG
CAATTAATTGGAGGAGATCCATTTGAACTTGACTTCAATGGAGATAACGACATTATAAATTCTAATGACT
TGAAAGTTGATGCTGAAACGCTACTAAATTCAGAGAACGTTCACCTACAGGCTCCTCAACCCAATAACAA
TAGTAGTAATAATAATAACGTTTCGTCACCATCGGGCTCAAATAAGATGCCTACAACCCCAATAATTTCA
ATTGAGGAATATGATGATAATAATAAAAACTCTAACGATGATGAGTATGCGATTGATATGGACTCTTCAA
ATGCTCTCCAAGAGAATAGAGGTTTCCTCGGTATATCATTACTACCGGCGGAGGACTCGGACGCAACACA
TGACGAAATATTACAAGGAAGGAAACAAAAGCTGAAAAATAGAAGGGTATCTCAAAGTAGTTCCCGTAGG
TCTTCTCGATCATCCATGCGCAGCTTAACACCTGAAGAAAAAGCCCGTTCATTGAGTTCGAACAGGAATA
AATTATTGGAAATGGCTGACTTATTACCAAAATCGCCTTCATCGAACAACGGTTCGAATAATAACTCTAG
AAGATCTTCCTTCTATGAGGAAAGTGAAGATATTTCCATGGATACCAACATATCCGAAAATAACAATACC
AACAATAATACTGGCACCGATTATGTATGTGAAGTTTGTGGGAAAGTTTTCTCTCGACCATATAACCTGA
AGTCACATTTGAGAACACATACAGATGAAAAGCCATACCAATGCTCTATATGTGGGAAGGCATTTGCAAG
ACAGCACGATAAAAAGAGGCACGAGGATTTGCATACTGGTAAAAAACGGTATGTATGTGGTGGTAAATTG
AAGGATGGTACTTTTTGGGGGTGTGGTAAGAAGTTTGCAAGAAGTGATGCCTTAGGTAGACATTTTAAGA
CGAGTAGCGGGAGGAAATGTATCACCCCACTATACGAAGAGACCGCAAGAGAGAGGAATCTCCCTAGTAT
AGACGATACGAATATTCAAGCAACTGAGATGGGTGTTACTTTGGAATA
Protein Sequence 
>gi|50294466|ref|XP_449644.1| hypothetical protein [Candida glabrata CBS 138]
MGDNEEDRRKKFLNGLQLQPDQDNMFLDQYLDQAAELQRHLQGNNSMNGDVYEQDNNNHNFSTGQNILSE
STFSPSSDMSNPVSNLFNSKSINFSDMPYEMGVGEETPNDDRDRQDSNQNNNNNLMNTPTLKIECFDEDG
VFLPGDTTNDPFTQDSGPKYDSSQNINAGIVSDMNNFENMDSNFLDFGGDNQVSKEDGTYLDLYDNNLKN
ASTEKIASSNNLSVSRNSEDNLSRVSSTLNSPFMQPTDRSVSPILSPPVMYLGDHSHTDDNDDVVSILSN
NSNILLPVNSHGYKYVTDFNQLGQLIGGDPFELDFNGDNDIINSNDLKVDAETLLNSENVHLQAPQPNNN
SSNNNNVSSPSGSNKMPTTPIISIEEYDDNNKNSNDDEYAIDMDSSNALQENRGFLGISLLPAEDSDATH
DEILQGRKQKLKNRRVSQSSSRRSSRSSMRSLTPEEKARSLSSNRNKLLEMADLLPKSPSSNNGSNNNSR
RSSFYEESEDISMDTNISENNNTNNNTGTDYVCEVCGKVFSRPYNLKSHLRTHTDEKPYQCSICGKAFAR
QHDKKRHEDLHTGKKRYVCGGKLKDGTFWGCGKKFARSDALGRHFKTSSGRKCITPLYEETARERNLPSI
DDTNIQATEMGVTLE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: crz1 mutant is attenuated in mice (Miyazaki et al., 2010).
References
Miyazaki et al., 2010: Miyazaki T, Yamauchi S, Inamine T, Nagayoshi Y, Saijo T, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S. Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata. Antimicrobial agents and chemotherapy. 2010; 54(4); 1639-1643. [PubMed: 20100876].