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mxiA from Shigella flexneri 5a

Victor ID 47
Gene Name mxiA from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876517
NCBI Protein GI 13449094
Locus Tag pWR501_p155
Protein Accession NP_085310.1
Other Database IDs UniProtKB-ID: MXIA_SHIFL
UniRef100: UniRef100_P0A1I5
UniRef90: UniRef90_P0A1I5
UniRef50: UniRef50_P0A1I5
UniParc: UPI000012FAAA
EMBL: M91664
EMBL: D10999
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL: M81458
EMBL-CDS: AAA26529.1
EMBL-CDS: BAA01771.1
EMBL-CDS: CAC05822.1
EMBL-CDS: AAK18466.1
EMBL-CDS: AAL72333.1
EMBL-CDS: -
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093209
EnsemblGenome_TRS: EBESCT00000094165
EnsemblGenome_PRO: EBESCP00000090372
GenomeReviews: AF3
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 119773
Gene Ending Position 121833
Gene Strand (Orientation) +
Protein Name invasion protein
DNA Sequence 
>gi|13448939:119773-121833 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
AGTGATCCAGTCTTTTCTTAAGCAAGTAAGTACTAAGCCTGAATTAATTATATTAGTGCTTATGGTTATG
ATCATTGCTATGTTGATCATACCATTACCTACATACCTTGTTGATTTTTTAATAGGGCTTAATATTGTAC
TTGCTATTCTCGTTTTTATGGGATCATTTTATATTGAAAGAATATTGAGTTTTTCTACATTCCCTTCGGT
TTTGTTGATAACGACATTATTTCGTCTCGCTTTATCAATAAGTACTAGTCGACTAATTTTAGTTGATGCG
GATGCGGGTAAAATTATTACTACATTTGGCCAGTTTGTCATTGGTGATAGTCTGGCTGTAGGTTTTGTTA
TTTTTTCAATAGTAACTGTTGTGCAGTTCATTGTTATAACAAAAGGATCTGAAAGGGTTGCGGAGGTAGC
TGCTCGCTTTTCTCTTGACGGTATGCCGGGGAAACAAATGAGCATTGATGCGGATTTAAAGGCTGGAATT
ATTGATGCCGCAGGAGCTAAAGAAAGACGCAGTATTCTGGAACGTGAGAGTCAATTGTATGGTTCATTTG
ATGGAGCAATGAAGTTCATTAAAGGTGATGCAATTGCTGGCATCATTATTATTTTTGTCAATTTAATAGG
AGGTATTTCTGTTGGTATGAGTCAACATGGAATGTCCCTATCTGGTGCATTATCTACTTATACCATACTA
ACTATTGGTGACGGATTGGTCTCTCAGATTCCTGCTCTGTTAATTTCTATAAGTGCAGGATTTATCGTTA
CAAGAGTTAATGGTGATAGCGATAATATGGGACGTAACATAATGTCCCAGATATTTGGGAATCCTTTTGT
TCTCATTGTTACATCAGCTCTTGCCTTGGCGATAGGGATGTTGCCAGGTTTTCCGTTTTTTGTTTTTTTC
CTGATAGCAGTTACTTTGACGGCTTTATTCTATTATAAAAAGGTCGTAGAAAAAGAAAAAAGTCTGTCTG
AGTCTGATTCTAGTGGCTATACTGGTACATTTGATATTGATAATAGCCATGACTCATCTTTGGCAATGAT
AGAAAATCTGGATGCTATTAGTTCAGAAACCGTTCCTTTAATTTTATTATTTGCCGAAAATAAGATAAAT
GCAAATGATATGGAAGGTCTTATTGAAAGGATAAGAAGTCAGTTCTTTATTGATTATGGTGTCAGGCTTC
CAACTATTTTATATAGAACAAGCAATGAGCTTAAGGTCGATGATATTGTTTTGTTAATAAATGAGGTGCG
TGCCGATAGTTTTAATATATATTTTGACAAAGTGTGTATTACAGATGAAAATGGAGATATAGATGCTCTA
GGTATTCCTGTTGTTTCAACTTCATATAATGAACGTGTTATTTCTTGGGTAGACGTTTCATATACAGAAA
ATCTAACTAATATTGATGCTAAAATTAAAAGTGCTCAAGATGAATTTTATCACCAGTTGTCACAAGCTTT
ATTAAACAACATAAATGAGATTTTTGGTATACAAGAAACAAAAAATATGTTAGATCAGTTTGAAAATCGG
TATCCTGATCTATTAAAGGAAGTCTTCCGACATGTGACTATACAGAGAATTTCTGAGGTATTACAAAGAT
TGCTTGGAGAAAATATTTCTGTTCGCAATTTAAAACTTATTATGGAGTCTTTGGCGCTTTGGGCTCCCAG
AGAAAAAGATGTCATAACATTAGTTGAACATGTCCGTGCATCACTTTCTAGGTATATTTGTAGTAAAATA
GCTGTTTCTGGTGAGATTAAAGTTGTGATGCTTTCCGGATATATTGAGGATGCAATAAGAAAAGGGATAA
GGCAAACCTCTGGTGGCTCTTTCTTGAATATGGATATAGAGGTTTCGGATGAGGTAATGGAAACTTTAGC
ACATGCTTTGAGAGAATTGAGAAATGCAAAAAAAAATTTCGTTCTTTTGGTATCAGTAGATATACGTAGG
TTTGTTAAAAGACTTATAGATAACAGATTTAAGAGTATACTCGTTATATCGTATGCTGAGATTGATGAAG
CATATACCATTAATGTATTAAAGACTATTTA
Protein Sequence 
>gi|13449094|ref|NP_085310.1| invasion protein [Shigella flexneri 5a str. M90T] MIQSFLKQVSTKPELIILVLMVMIIAMLIIPLPTYLVDFLIGLNIVLAILVFMGSFYIERILSFSTFPSVLLITTLFRLALSISTSRLILVDADAGKIITTFGQFVIGDSLAVGFVIFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKAGIIDAAGAKERRSILERESQLYGSFDGAMKFIKGDAIAGIIIIFVNLIGGISVGMSQHGMSLSGALSTYTILTIGDGLVSQIPALLISISAGFIVTRVNGDSDNMGRNIMSQIFGNPFVLIVTSALALAIGMLPGFPFFVFFLIAVTLTALFYYKKVVEKEKSLSESDSSGYTGTFDIDNSHDSSLAMIENLDAISSETVPLILLFAENKINANDMEGLIERIRSQFFIDYGVRLPTILYRTSNELKVDDIVLLINEVRADSFNIYFDKVCITDENGDIDALGIPVVSTSYNERVISWVDVSYTENLTNIDAKIKSAQDEFYHQLSQALLNNINEIFGIQETKNMLDQFENRYPDLLKEVFRHVTIQRISEVLQRLLGENISVRNLKLIMESLALWAPREKDVITLVEHVRASLSRYICSKIAVSGEIKVVMLSGYIEDAIRKGIRQTSGGSFLNMDIEVSDEVMETLAHALRELRNAKKNFVLLVSVDIRRFVKRLIDNRFKSILVISYAEIDEAYTINVLKTI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiA mutants were attenuated in invasion of HeLa cells (Andrews et al., 1991).
References
Andrews et al., 1991: Andrews GP, Hromockyj AE, Coker C, Maurelli AT. Two novel virulence loci, mxiA and mxiB, in Shigella flexneri 2a facilitate excretion of invasion plasmid antigens. Infection and immunity. 1991; 59(6); 1997-2005. [PubMed: 2037361].