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YHB1

Victor ID 4696
Gene Name YHB1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3647353
NCBI Protein GI 68490250
Locus Tag CaO19.3707
Genbank Accession AACQ01000217
Protein Accession XP_711046
Taxonomy ID 237561
Chromosome No R
Gene Starting Position 7816
Gene Ending Position 9012
Gene Strand (Orientation) -
Protein pI 5.57
Protein Weight 43139.49
Protein Length 398
DNA Sequence 
>gi|68490269:7816-9012 Candida albicans SC5314 chromosome R Ctg19-10188, whole genome shotgun sequence
TTTAAGGATCGTAAGGACCAAAATATTCAAGCTTGACAGGAACATTCTTTTTACCCAAATGTTCTTTGAT
ATCTTTCATAAACTCTCTTGGACCAACAAGGTACACATCATGTTCTGGAGCAATAAAATCTAAATCATCA
GTAGTCAATTTACGGTTAAATGCTTTATCAATAACAATCTTGTCATCGGTGTTATTGTCTTCAGAAAAGT
ATTCAATGGCTTGGAATTTGTCACCAAATTTGCTCTTGTATTCTTTGAAAAGGTTGCCGAAAGCTCTAGT
TTCAGCAGATCTGTTTGAGTACAAAAGTTTGACATTTTTTCCTTCTTCTAAAGCACGTTCAATCATTGAT
AACAATGGGGTAATACCAATACCACCAGCAACGAAAATCAATTCCTTGTCTGTAGCTGGGTCATAGACAA
AATTACCAGCAGGAGGAGCAACTTTCAAAATATCGCCAACTTTCAAATTGTTATGAATATAACCTGAGAT
CTTACCACCTGGGACATGTCTAACAGAAATTCTATATTCATTTTCTTTAGGGAATTCTGACACTGAATAT
TCACGAGAAATCTCAAATTCTTCACCAGGTAATTTCCATCTGAAACACAAGTATTGACCACGTTCAGGTT
TTGGTAATGGTAAAAGATCTTTATCAACTGGAGTGAAATAAACGGATTTGACATCTTTACATTCTTGAAC
AATTCTTGTCACTTTGAAATCTTTAAACCAACGCCATGGTTGTTTGGCATATTCTGCGGCTTCTAAATCG
ATCAATAATTTAGCCAAGTTCCCGTAAGCAATAGTCCAAGCTTCCAAAAAGTCTTTGTTAGCAATTTCTG
GAGGTAATAATTCAACCATGGTTTGAATAAGACAAGTACCAACAATTGGATAATGTTCTGGTAACACTTG
TAAACCAATGTGTTTAACAACAATTTGTTTAACAAAATCGGTCAATGGAGTCAAATCTTCAATGTTTTTA
GCATAATTCAATAAAGCAAATGCTAAAATTTTTGGTTGTCTCAATAATTTTTGATCAGTGGTGTTGAAAA
ATGGTTTAACTTCATCATAATTTCCAATCATACGTTGATAGAATTTTTGAGTCAATGTTTCACCGGCTTC
TTCTAAAATTGGAACGGTATCCAAAATGATTTTGATTTGGGCTGGAGTTAATTGTTTGGTTTCGTATTCG
ACTGTCA
Protein Sequence 
>gi|68490250|ref|XP_711046.1| likely flavohemoglobin [Candida albicans SC5314]
MTVEYETKQLTPAQIKIILDTVPILEEAGETLTQKFYQRMIGNYDEVKPFFNTTDQKLLRQPKILAFALL
NYAKNIEDLTPLTDFVKQIVVKHIGLQVLPEHYPIVGTCLIQTMVELLPPEIANKDFLEAWTIAYGNLAK
LLIDLEAAEYAKQPWRWFKDFKVTRIVQECKDVKSVYFTPVDKDLLPLPKPERGQYLCFRWKLPGEEFEI
SREYSVSEFPKENEYRISVRHVPGGKISGYIHNNLKVGDILKVAPPAGNFVYDPATDKELIFVAGGIGIT
PLLSMIERALEEGKNVKLLYSNRSAETRAFGNLFKEYKSKFGDKFQAIEYFSEDNNTDDKIVIDKAFNRK
LTTDDLDFIAPEHDVYLVGPREFMKDIKEHLGKKNVPVKLEYFGPYDP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CaYHB1 mutant is still lethal in mice but has reduced virulence compared to the wild type (Ullmann et al., 2004).
References
Ullmann et al., 2004: Ullmann BD, Myers H, Chiranand W, Lazzell AL, Zhao Q, Vega LA, Lopez-Ribot JL, Gardner PR, Gustin MC. Inducible defense mechanism against nitric oxide in Candida albicans. Eukaryotic cell. 2004; 3(3); 715-723. [PubMed: 15189992].