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SPT3

Victor ID 4688
Gene Name SPT3
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3638977
NCBI Protein GI 68473155
Locus Tag CaO19.7622
Genbank Accession AACQ01000032
Protein Accession XP_719383
Taxonomy ID 237561
Chromosome No R
Gene Starting Position 155347
Gene Ending Position 156333
Gene Strand (Orientation) -
Protein pI 9.24
Protein Weight 36737.14
Protein Length 328
DNA Sequence 
>gi|68473266:155347-156333 Candida albicans SC5314 chromosome R Ctg19-2518, whole genome shotgun sequence
TTTAGATCAATCTAGTTCTGGTTTTAAGTACACCACCACCAAACGCTCTTGCGGCTTTGTGTTTAAAATC
AGTTGATTGTAACCTTCTCCATGCTTCCTCTATATGATATGGCATTATTGGAGTGGTGAATTCGTCTGGT
TTATCAAATAAGTATTTTCTCTTAACTGGTTTCTCCTTATTGTCGACAATTTGTTTTAGTCTCTGTATAT
GATGTAATTTATCTTCGGAATTTTTAATATTCATGGCCTCCTCTGTTAAGGAACACACAATCTCAAAAGT
TAAAAACCCTAGGATATCAATAACATCGTCATTGGGTCTGGTATCACATAATTGACTCATTTGGGCCCAT
TCTCTAAAACGCTTACCCTTTCTAAAAGTAAATGACGCCTGTCGACACTCACTCCAATGAACGTACTCTT
CTCTAGTCATATTTTTAGTTCGATCATCTGCCATTTTCAATTTTTTCAACCTCGCTATAGAGGCAGCTTT
CTCTTCGTCATCGATAAGTTCATTTTCTTCTTGTGTTTCTAAATGCTGTTCACTAAACATAAATTGCAAT
TCCCAAGGCAATCTTATCTTGGACTTTTTGTACCTTGAAAGCATTTTTGAAGAATCATTTGATTGGGATT
GTGACGGGCCACCGGCTCCTACACCAACATCATTGGTATTTTCAATCAAGGATTCAGTTCCACCACCTTC
TTGATCTTTGGCATTTTTACGAACATCCTTCCAAGATAAATAAGTTCGTAAACGATTCACTTTTGCCTTA
TCGTGTCGAATCAAAAAAATCACGTCTTCTGGTATAATACTTCTGCTACCTCGAGAATTTGCTGTTTTTG
TTGATTGCCTCAATATTTCAATAACTTGGCCTCGTACGATATCTTCAATTATCGATGTTGTTTCTATTGG
TGGATCATTTGCTTCTCCCAGCACAAACATCATCTGCAGAATCTCAATCCTGTATTTGTACTTGTTATCA
GAGGCCA
Protein Sequence 
>gi|68473155|ref|XP_719383.1| hypothetical protein CaO19.7622 [Candida albicans SC5314]
MASDNKYKYRIEISQMMFVSGEANDPPIETTSIIEDIVRGQVIEILRQSTKTANSRGSRSIIPEDVIFLI
RHDKAKVNRLRTYLSWKDVRKNAKDQEGGGTESLIENTNDVGVGAGGPSQSQSNDSSKMLSRYKKSKIRL
PWELQFMFSEQHLETQEENELIDDEEKAASIARLKKLKMADDRTKNMTREEYVHWSECRQASFTFRKGKR
FREWAQMSQLCDTRPNDDVIDILGFLTFEIVCSLTEEAMNIKNSEDKLHHIQRLKQIVDNKEKPVKRKYL
FDKPDEFTTPIMPYHIEEAWRRLQSTDFKHKAARAFGGGVLKTRTRLI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spt3 mutant is avirulent in mice (Laprade et al., 2002).
References
Laprade et al., 2002: Laprade L, Boyartchuk VL, Dietrich WF, Winston F. Spt3 plays opposite roles in filamentous growth in Saccharomyces cerevisiae and Candida albicans and is required for C. albicans virulence. Genetics. 2002; 161(2); 509-519. [PubMed: 12072450].