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sod1

Victor ID 4685
Gene Name sod1
Sequence Strain (Species/Organism) Candida albicans
NCBI Nucleotide GI 3005096
NCBI Protein GI 3005097
Protein Accession AAC12872.1
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name Cu,Zn-superoxide dismutase
DNA Sequence 
>gi|3005096|gb|AF046872.1| Candida albicans Cu,Zn-superoxide dismutase (sod1) gene, complete cds
GGTACCCCAACTTTGTCACTGTGGCTTCAACTGAATTAGTAGGACTAGAATTACTTAGTACACGACCTTA
ATTTGTCACATACATGCTTTACTTTCTCCGATCCAACGGGGATTCTTTATTATTATTTGCTTATGACACA
CACACAGCAAGTTTTAGTTAACTCCTTTCCCGCTCCTTTGCTTACCCACCCCCAACAAGCAAACAAGCGG
ACAGAAAAATTCCACAACCTTCCAAAACTTTTTCACAGTTGATTTCTTTCTCCCTTTTTTTTTCCCCAAT
TATTCAACACTCTTTTTTTTTGAAAAGATCAATTCAATTCAATTCAATTATCAACATATATATAATTAAA
AATGGTTAAAGCTGGTATGTAATTCAATGCAATTGTATCTTAATGGTTGCAAAATAATAGAAAAAGAAAC
AATTATAATCTAGGGTCTTGGTTCCAACCTTCTCAGCGAAAGAGTGAATTTCAAATTACCAATTGAAGTA
ATTTCTAATTTGCTCATAATTGTATTCTTCCAAAAACATGGAAACAAAGCATAACTATGCAACACAATTA
GATATATGAATATAATACTAACATATTAAACCTTTTCTTTTCTTTTCAGTCGCTGTTGTCAGAGGTGATT
CAAAAGTCCAAGGTACCGTTCATTTTGAACAAGAATCCGAATCCGCTCCAACCACAATTTCCTGGGAAAT
TGAAGGTAATGATCCAAATGCCTTGAGAGGTTTCCATATTCATCAATTTGGTGATAACACCAATGGTTGT
ACTTCTGCTGGTCCTCATTTCAATCCATTTGGTAAACAACATGGTGCTCCAGAAGATGATGAAAGACATG
TTGGTGATTTAGGTAATATTTCTACTGATGGTAATGGTGTTGCTAAAGGTACCAAACAAGATTTATTGAT
TAAATTGATTGGTAAAGATTCTATCTTGGGTAGAACTATTGTTGTTCATGCTGGTACTGATGATTATGGT
AAAGGTGGTTTTGAAGATTCTAAAACTACTGGTCATGCTGGTGCTAGACCTGCTTGTGGTGTCATTGGCT
TGACCCAATGAATAGATGAGCCAAGATTGCCATCATCATCAACAATCCAACCCAAGAATAAGTTATGAAT
GAAAAAAAAAAAACTAAATTGACTGACTGGTCTTGTCATTTTTGTTTATAACTATTTAGTAGTTTTGGAA
GCAATAAAAAAAAGTTAAATATGATGTATGTTTATTTGAAGTGAATACATATTCTATGATAAAGTTATAA
TCACTAGTAAATATAACGACTATTCTCTAGTTGAGCTTACAATATTATTGAAAAGGTGTGTTTTTAATAA
ATTAATTTAAATTTAAATCTTATTCTATACACCGAAAATAGTATCAAATTCAACCAAAAATATACAAAGA
ACTTCAACATTAATATTTAAAGTTGGTTCAAATATAATGCCCACATTTTTCAATGTCATTCGATTAATAT
CACTTTGTTGAATAATTTGTCTCAAAAAACTAAAAACCAAAAATGATAAATCATAATGAATTTCATCAAC
ATTATTAACATCATTAAAATAATCCCTAAATACAATTGCCAAATCCGAATTC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sod1 mutant had increased susceptibility to macrophage attack and had attenuated virulence in mice (Hwang et al., 2002).
References
Hwang et al., 2002: Hwang CS, Rhie GE, Oh JH, Huh WK, Yim HS, Kang SO. Copper- and zinc-containing superoxide dismutase (Cu/ZnSOD) is required for the protection of Candida albicans against oxidative stresses and the expression of its full virulence. Microbiology (Reading, England). 2002; 148(Pt 11); 3705-3713. [PubMed: 12427960].