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SIT4

Victor ID 4683
Gene Name SIT4
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3647982
NCBI Protein GI 68491579
Locus Tag CaO19.12667
Genbank Accession AACQ01000273
Protein Accession XP_710419
Taxonomy ID 237561
Chromosome No R
Gene Starting Position 10542
Gene Ending Position 11486
Gene Strand (Orientation) -
Protein pI 5.07
Protein Weight 33318.97
Protein Length 314
DNA Sequence 
>gi|68491586:10542-11486 Candida albicans SC5314 chromosome R Ctg19-20220, whole genome shotgun sequence
GTTACAAAAAATAATCACTTCTTTGTTGTTTGTTGGCATTGTTCTTGACTGATAAGTCACCATCTTGAAC
GGCACTGAATATCTTGAAATTAGGTTCTAAATCTTCATCGACTTGCATAACACTGGCAACATTCCCACAT
CTATAACAGTAATTTGGAGCAGACCATACTGTGACAACATCTTTTTCCTTAAAATGGTAACGAAACCCTT
CCATTACCAACTGGTGTGCTCTGGCAATTAATTGCAAATTGTTGATGTGATTGAATTCTCGCGACACTTT
TGAGCCAAACAACCATCCAGCCCCTCTAGGCGATACTGCCCAAGTGTCAATGTTATCTGGGTCTGACCAC
ACCAAGTCACAGAAACCACCTTCGTGAGGAACTTCTTGAGCTCTAGACAACACTCTAATCTGGTCCAACA
TTCTGATTTCTGGAGATAACCCACCATGTACACATAAAATTTTGCCATCTATTATTGCTGCTAAAGTTAA
GAAATCAAAAACTTGACAACAATATTTCCAAACAGTGGTTGAGCCGTATTTTGTTAAACATTCTTCATAA
AACCCATATACTTGTGTGATTTGTCTCGATTCGTGATTTCCTCTTACCAAAGTAATTCTGTGAGGATATT
TTACTTTTAAAACCATTAATAAAGTGAATGTTTCCAAGGAAAAATAACCACGATCGACATAGTCTCCCAA
GAAAATAAAGTTGGTTTGATTGTCATCTGAAGGTAAACCTCCTGCAGTTCTGAATAATTCCAATAAATCG
TGGAATTGTCCATGTATGTCACCACAAACCGTCACAGGGGACTGTACAGGTTGAATATTGGATTCTTCCA
TTAGTAATTCTTTGACCAATTCACATAACTGTTTCATATCAGATTCTGATAATGAAATGCAATTTTTTAT
CTGTTCCAACCACTGATCTGGACCTCTTTCTCCCA
Protein Sequence 
>gi|68491579|ref|XP_710419.1| potential type 2A-related protein phosphatase [Candida albicans SC5314]
MGERGPDQWLEQIKNCISLSESDMKQLCELVKELLMEESNIQPVQSPVTVCGDIHGQFHDLLELFRTAGG
LPSDDNQTNFIFLGDYVDRGYFSLETFTLLMVLKVKYPHRITLVRGNHESRQITQVYGFYEECLTKYGST
TVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFCDLVWSDPDNIDTWA
VSPRGAGWLFGSKVSREFNHINNLQLIARAHQLVMEGFRYHFKEKDVVTVWSAPNYCYRCGNVASVMQVD
EDLEPNFKIFSAVQDGDLSVKNNANKQQRSDYFL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sit4 mutant is attenuated in mice (Lee et al., 2004).
References
Lee et al., 2004: Lee CM, Nantel A, Jiang L, Whiteway M, Shen SH. The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans. Molecular microbiology. 2004; 51(3); 691-709. [PubMed: 14731272].