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ARN1

Victor ID 4682
Gene Name ARN1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3642307
NCBI Protein GI 68479941
Locus Tag CaO19.2179
Genbank Accession AACQ01000076
Protein Accession XP_716020
Taxonomy ID 237561
Chromosome No 2
Gene Starting Position 33830
Gene Ending Position 35644
Gene Strand (Orientation) +
Protein pI 8.44
Protein Weight 61559.82
Protein Length 604
DNA Sequence 
>gi|68480036:33830-35644 Candida albicans SC5314 chromosome 2 Ctg19-10141, whole genome shotgun sequence
CATGACATCTTACCAGTCTTCCAATAATCATTCTTCAGAAGAAGATAAACACTTGTCCGGAGATGAAAAG
ACGTTTTCGCCATCCGATATAGTTGAAAAGGCTATAGTAGAGGAAAAATCCATTGGGGTTGAAAAAGCAG
AAATCTTAGCTAATCAATGGAAACATACATTTTGGTTCAAATTGCTTTTAGGGTTTTCTGCATTTCTTTG
TGGTTATGCTTACGGTCTCGATAGTCAAACTCGATATGTTTACACTGCTTATGCAACTGCCAGTTGGTCA
GAACACAGTTTATTAACAACCGTTAACGCTATTACTGGGGTGGTGGCAGCTGCCAGTCAACCCGTCTATG
CCAGATTGTCGGATGTCCTTGGTCGTTTGGAGTTGTTTATTGTTGCAGTGTTGTTTTACGTGGTTGGTAC
TATTATTGAATGCCAGCTGCCAACCATTAATGCTTATGTTGCTGGTGCTGTGTTGTTCCAAATTGGATAC
AGTGGTATCATTATTATGTTGTTATTCATTTTGTCTGATTTCTCAAGTTTGAGATGGAGATTGTTTTTTA
CGTTATGTCCATCATTCCCGTTCATTATCAACACTTGGATTTCCGGTAATGTTACTGCTGCCGTTGGTAC
TAGATGGAAATGGGGTATCGGGATGTGGGCTTTTATACTCCCATTGTCATGTATTCCTCTTGTGTGCTGT
ATGATTCATATGCGTTGGCTAGCTGGTAAGACAGAAGAATGGAGAGTTTTCAAGCAACGTAAAACAAAGT
TCCAAGAATTGGGTGTAGCAGGATTCTCCAAGTACTTGTTTTGGAGATTGGATGTTATTGGATTGTTGTT
GTTAACTGTATCATTGGGTTGTTTATTGGTCCCATTGACACTTGCTGGTGGTATCAAAGAAACTTGGAAA
AAAGCTCATATCATTGTGCCAATAGTCATTGGAGGTGTCTTGATTCCTGTTTTCCTTTTATGGGAAGGTT
ACGGAGCTCGAGACCCAATTATACCACTTCACTTAATGAAGGATAGAGGTATTTGGTCCGTCGTTTCAAT
TTCCTTGTTTTTCGACTTTGTTTTCGCAGTCGAATCTAACTTCTTATACACTGTGTTAATGGTGGCTGTC
AACGAATCACAATCCTCTGCTACTAGAATTGCAAGTCTTTCATCATTTGTATCTGTTGTCACGGGTTTTA
TTTTTGGGTTGTTCGTTGTTTATTTCAGACGTTTGAAAGGATTTGTTGTATTTGGATGTGCTATGTGGAT
GGTTGCATTTGGTATTATGTATCATTTTAGATCTCAATTACATGCACATGCAGGGATCATTGGTGGTATG
TGTTTGATGGGATTCGGTACCGGGTTCTTCTCATACCCAATTAATGTCAGTGCCCAAAGTTGTGTTAGTC
ACGAGCATATGGCTGTGATTTCATCGGCATTGTATACCACCTATAGAATTGGATACGCTGTTGGTTCGTC
AGTAGCAGGTGCAATTTGGTCCCAGATGTTGTATTCAAGATTAGTCAAATACCTTGGCGATTCTACTTTG
GCCACAAGCGTTTATACCGATCCATACACATTTATTGCACAATATGTTTGGGGCACTCCAGAAAGAGAAG
CTGCAGTCAAAGCTTATGGTGAAGTACAAAGAGTATTAATGAGTGTTTGTATTGCATTTGTTGCTCCTAT
GATAGTATCTGCACTTTTCATGAGAGACCACAAATTAACCAATGAACAAAGCTTGGAAGATGTAGAAAAG
CAAGAAGAGAAGGACTCGTTGGCCAATTTCTTCGGCAATTTCAAGAAGAAAAGAGTAGCTGTTTA
Protein Sequence 
>gi|68479941|ref|XP_716020.1| ferrichrome-type siderophore transporter [Candida albicans SC5314]
MTSYQSSNNHSSEEDKHLSGDEKTFSPSDIVEKAIVEEKSIGVEKAEILANQWKHTFWFKLLLGFSAFLC
GYAYGLDSQTRYVYTAYATASWSEHSLLTTVNAITGVVAAASQPVYARLSDVLGRLELFIVAVLFYVVGT
IIECQSPTINAYVAGAVLFQIGYSGIIIMLLFILSDFSSLRWRLFFTLCPSFPFIINTWISGNVTAAVGT
RWKWGIGMWAFILPLSCIPLVCCMIHMRWLAGKTEEWRVFKQRKTKFQELGVAGFSKYLFWRLDVIGLLL
LTVSLGCLLVPLTLAGGIKETWKKAHIIVPIVIGGVLIPVFLLWEGYGARDPIIPLHLMKDRGIWSVVSI
SLFFDFVFAVESNFLYTVLMVAVNESQSSATRIASLSSFVSVVTGFIFGLFVVYFRRLKGFVVFGCAMWM
VAFGIMYHFRSQLHAHAGIIGGMCLMGFGTGFFSYPINVSAQSCVSHEHMAVISSALYTTYRIGYAVGSS
VAGAIWSQMLYSRLVKYLGDSTLATSVYTDPYTFIAQYVWGTPEREAAVKAYGEVQRVLMSVCIAFVAPM
IVSALFMRDHKLTNEQSLEDVEKQEEKDSLANFFGNFKKKRVAV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sit1(ARN1) mutant was defective in infection of a reconstituted human epithelium as a model for human oral mucosa (Heymann et al., 2002).
References
Heymann et al., 2002: Heymann P, Gerads M, Schaller M, Dromer F, Winkelmann G, Ernst JF. The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infection and immunity. 2002; 70(9); 5246-5255. [PubMed: 12183576].