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SAP7

Victor ID 4681
Gene Name SAP7
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3644735
NCBI Protein GI 68484925
Locus Tag CaO19.8376
Genbank Accession AACQ01000123
Protein Accession XP_713601
Taxonomy ID 237561
Chromosome No 1
Gene Starting Position 15853
Gene Ending Position 17619
Gene Strand (Orientation) -
Protein pI 4.35
Protein Weight 58133.71
Protein Length 588
DNA Sequence 
>gi|68484984:15853-17619 Candida albicans SC5314 chromosome 1 Ctg19-20073, whole genome shotgun sequence
TTTACTCGATAGGAACAACGGCATGGTTATCATTATAAGCAGCTTGAGCAATAGAAATGACATGGTCTTC
TAAGTCAAACACAGCATAGACACTTCTCATAAAGTTGTCACCCAAAATTGAATGAGTACCTGGTAAAATA
CCAAATACACACAATTCAGCACCACTAGCATAAGTACCGACTGAAATAACAAATTCAGATGTTGGTACTT
TAATGTATTGTTCATTTTTGAAATTGAATTCCAAATAATTACCAGGATTACCTACCCAACATGGAACTTC
ATAAGCTTTCCCAGCATCATTATAAGTAACATTACCATAAAGTCCAACAATTGATTCAACTTGGTCTTTG
GACAAGTAACTGTATGTAGTTCCGGTATCCAATAAAGTTGGAGTGTCTTTGAGATCAACACCACCATTAA
AAGAATCGGTACCATTATAGATAACAGCACCTACTTTTGGATGGTTACTTCCAGCAGGAAGACCATAAGC
ATTAGTATAATTGTTCAATGATGAAGCAACTGAAGTCAATGGGATTTGAGAATAAACATATTTATCATTA
GATTGAACAATATCAAAAGCTTTCAAATCCCCAGTATATTTGGCATGATCAATACCACCAAATAAAATAT
AACCTTGGACAGCATCACGAGAATCAAGGTATAAGGAATAAGCAACTTTAGCAATCAAATTTTGTTCTTT
CATAGCAAATGGCAAATTGGTGTATTTTGATTTAACGGCTTCCAATTCAGGATAACCAACACCGAAAACA
CCAATACTAGAAGTAGTGTTATCAATAACGGCAAAGTTGGCATTTTCAATCAGAAATCCATCAGCAAATG
TAATATTATCTTGACCCATAGTACCTGATGCCTTATCACCGTCATAATAACTGATGGAGTAATCAGTTTT
GTTATCATGCCATGTAGAAGATTTCAGTTTATCAAAAACACCGTATTTGTCACAATCAATTGACCCTCCA
TTGACTTTACATTGAGAATTTCCTGAAGAAATAAACCATAAATCAGAAGATCCAGTATCAATCATAACTT
GAACTTCTTGAGCTGGTGAACCAACTTTCAAAGTAGCAGTATATAATGTTTGAGTGTTATCTAAACTGAG
GAAAAAAGCACCAGTTTTTTTGTTGGCAGATGAAGAAGGTTGACTATCTTCTGATGGTTGCGAAGAGGAA
GCAGCTTCCAGTGAAGAAGAAGAAGATGCCGAGGAAGCTGGGCCAGGAGCAGTTGATTCAACGCTCTTGC
TTGTTGGTTGTTCGACTTGTGAGACAGCACTTGGAGTGAAATCTGCATCTTTGGAACCATTGTCAGATGA
AGTAGGTGCTTTATTCAAACCGATTAAATTCCAAAAATCAGTTGAAATTGAGTTCATTAAATCATCTAAA
GAAAATCCAGTTTTGGATGGATCAGTATCCTTATTATCAGTGGAGGATGGACCATTAGAACCTTTTTGTG
CTGATGAAGAGGGCAATGACACTTCATATTTCACACTGTGTCCATTACCAGAATGTGTTCCTTGAATTGA
ACCACCGGAAAAGATCCCATTACCAAAAATAGGTTGAATGATTTGGTTTACATCATCTTCAACTGATTTT
GCTACACCATTTACAACATCAAAAATAGGTAAACGGTTAGGGAAATGTGCACTGCCTTCACCAGCTTGAA
GTTTGTGCACTGGTAAAGCAATAAAACCATCACCAATAACAGCAAGAGCTGTAGATGATAAAAGTAATAA
CTCTAATACTCTTTGCA
Protein Sequence 
>gi|68484925|ref|XP_713601.1| secretory aspartyl proteinase SAP7p [Candida albicans SC5314]
MQRVLELLLLSSTALAVIGDGFIALPVHKLQAGEGSAHFPNRLPIFDVVNGVAKSVEDDVNQIIQPIFGN
GIFSGGSIQGTHSGNGHSVKYEVSLPSSSAQKGSNGPSSTDNKDTDPSKTGFSLDDLMNSISTDFWNLIG
LNKAPTSSDNGSKDADFTPSAVSQVEQPTSKSVESTAPGPASSASSSSSSEAASSSQPSEDSQPSSSANK
KTGAFFLSLDNTQTLYTATLKVGSPAQEVQVMIDTGSSDLWFISSGNSQCKVNGGSIDCDKYGVFDKSKS
STWHDNKTDYSISYYDGDKASGTMGQDNITFADGFSIENANFAVIDNTTSSIGVFGVGYPELEAVKSKYT
NLPFAMKEQNLIAKVAYSLYLDSRDAVQGYILFGGIDHAKYTGDLKAFDIVQSNDKYVYSQIPLTSVASS
LNNYTNAYGLPAGSNHPKVGAVIYNGTDSFNGGVDLKDTPTLLDTGTTYSYLSKDQVESIVGLYGNVTYN
DAGKAYEVPCWVGNPGNYLEFNFKNEQYIKVPTSEFVISVGTYASGAELCVFGILPGTHSILGDNFMRSV
YAVFDLEDHVISIAQAAYNDNHAVVPIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sap7 mutant is attenuated in an intravenous model of systemic candidiasis in mice (Taylor et al., 2005).
References
Taylor et al., 2005: Taylor BN, Hannemann H, Sehnal M, Biesemeier A, Schweizer A, Röllinghoff M, Schröppel K. Induction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in mice. Infection and immunity. 2005; 73(10); 7061-7063. [PubMed: 16177393].