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SAP3

Victor ID 4677
Gene Name SAP3
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3635197
NCBI Protein GI 68465697
Locus Tag CaO19.6001
Genbank Accession AACQ01000004
Protein Accession XP_723210
Taxonomy ID 237561
Chromosome No 3
Gene Starting Position 296107
Gene Ending Position 297303
Gene Strand (Orientation) +
Protein pI 4.19
Protein Weight 39730.29
Protein Length 398
DNA Sequence 
>gi|68465710:296107-297303 Candida albicans SC5314 chromosome 3 Ctg19-10236, whole genome shotgun sequence
AATGTTTTTAAAAAATATCTTTATTGCTCTTGCTATTGCTTTATTAGCTGATGCTACTCCAACAACTTTC
AACAATTCTCCAGGGTTTGTTGCTTTGAATTTTGATGTTATCAAAACTCATAAAAATGTTACTGGTCCCC
AAGGTGAAATCAATACCAACGTCAACGTCAAGAGACAAACTGTTCCAGTTAAATTAATTAATGAACAAGT
TAGTTATGCTTCTGATATTACTGTTGGTTCCAATAAACAAAAATTAACTGTTGTTATTGATACTGGATCA
TCTGATTTATGGGTTCCTGATTCTCAAGTTTCATGTCAAGCTGGTCAAGGACAAGATCCAAATTTTTGTA
AAAATGAAGGAACTTATTCCCCAAGTTCTTCAAGTAGTTCTCAAAATTTGAATAGTCCATTTAGTATTGA
ATATGGTGATGGAACTACTTCACAAGGGACATGGTATAAAGATACTATTGGATTTGGTGGTATTTCTATC
ACAAAGCAACAATTTGCCGATGTTACTAGTACATCAGTTGATCAAGGGATTTTAGGGATTGGTTATAAAA
CTCATGAAGCTGAAGGTAATTATGATAATGTTCCTGTGACTTTAAAAAATCAAGGAATTATTTCTAAAAA
TGCTTATTCACTTTATCTTAATTCAAGACAAGCCACTAGTGGACAAATTATTTTTGGTGGTGTTGATAAT
GCTAAATATAGTGGGACATTGATTGCTTTACCAGTTACTTCTGATAATGAATTAAGAATTCATTTGAATA
CTGTAAAAGTTGCTGGACAATCCATTAATGCTGATGTTGATGTTTTGTTGGATTCAGGTACTACCATTAC
TTATTTACAACAAGGTGTTGCTGATCAAGTGATTAGTGCTTTTAATGGTCAAGAAACTTATGATGCTAAT
GGTAATCTTTTCTATCTTGTTGATTGTAATTTGTCAGGATCAGTTGATTTTGCTTTTGATAAAAATGCTA
AAATTTCCGTTCCAGCTTCTGAATTTACTGCTCCATTATACACTGAAGATGGTCAAGTTTATGATCAATG
TCAACTTCTTTTTGGAACTAGTGATTATAACATTCTTGGTGATAATTTCTTGAGATCAGCCTATATTGTT
TATGATTTGGATGATAATGAAATTTCATTAGCTCAAGTTAAGTATACTACTGCTTCTAACATTGCTGCTC
TTACTTA
Protein Sequence 
>gi|68465697|ref|XP_723210.1| secretory aspartyl proteinase SAP3p [Candida albicans SC5314]
MFLKNIFIALAIALLADATPTTFNNSPGFVALNFDVIKTHKNVTGPQGEINTNVNVKRQTVPVKLINEQV
SYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQNLNSPFSIE
YGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQGILGIGYKTHEAEGNYDNVPVTLKNQGIISKN
AYSLYLNSRQATSGQIIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTIT
YLQQGVADQVISAFNGQETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQC
QLLFGTSDYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sap3 mutant is attenuated in mice and guinea pigs (Hube et al., 1997).
References
Hube et al., 1997: Hube B, Sanglard D, Odds FC, Hess D, Monod M, Schäfer W, Brown AJ, Gow NA. Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence. Infection and immunity. 1997; 65(9); 3529-3538. [PubMed: 9284116].