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SAP2

Victor ID 4676
Gene Name SAP2
Sequence Strain (Species/Organism) Candida albicans CAI4
NCBI Nucleotide GI 20378981
NCBI Protein GI 20378982
Protein Accession AAM21050.1
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name secreted aspartic proteinase 2
Protein Note protease
DNA Sequence 
>gi|20378981|gb|AF481100.1| Candida albicans strain CAI4 secreted aspartic proteinase 2 (SAP2) gene, SAP2-1 allele, complete cds
ATGTTTTTAAAGAATATTTTCATTGGCCTTGCTATTGCTTTATTAGTCGATGCTACTCCAACAACAACCA
AAAGATCAGCTGGTTTCGTTGCTTTAGATTTCAGTGTTGTGAAAACTCCTAAAGCATTCCCAGTTACTAA
TGGTCAAGAAGGTAAAACTTCCAAAAGACAAGCTGTCCCAGTGACTTTACACAATGAACAAGTCACTTAT
GCTGCTGATATTACCGTTGGATCCAATAATCAAAAACTTAATGTTATTGTTGATACTGGATCATCAGATT
TATGGGTTCCTGATGTTAATGTTGATTGTCAAGTCACTTATAGTGATCAAACTGCAGATTTCTGTAAACA
AAAGGGGACATATGATCCAAGTGGTTCATCAGCTTCACAAGATTTGAATACTCCATTCAAAATTGGTTAT
GGTGATGGATCTTCATCTCAAGGTACTTTATATAAGGATACCGTTGGATTTGGTGGTGTTTCGATTAAAA
ATCAAGTTTTAGCTGATGTTGATTCTACTTCAATTGATCAAGGTATTTTAGGGGTTGGTTATAAAACCAA
TGAAGCCGGTGGTAGTTATGATAATGTCCCTGTCACTTTAAAAAAACAAGGAGTCATTGCTAAGAATGCT
TATTCACTTTATCTTAATTCTCCAGATGCTGCCACGGGACAAATCATTTTCGGTGGGGTTGATAATGCTA
AATATAGTGGTTCATTAATTGCATTACCAGTTACTTCTGATCGTGAATTAAGAATTAGTTTGGGTTCAGT
TGAAGTTTCTGGTAAAACCATCAATACTGATAATGTCGATGTTCTTTTGGATTCAGGTACCACCATTACT
TATTTGCAACAAGATCTTGCTGATCAAATCATTAAAGCTTTCAATGGTAAATTAACTCAAGATTCCAATG
GTAATTCATTCTATGAAGTTGATTGTAATTTGTCAGGGGATGTTGTATTCAATTTTAGTAAAAATGCTAA
AATTTCCGTTCCAGCTTCCGAATTTGCTGCTTCTTTACAAGGTGATGATGGTCAACCATATGATAAATGT
CAATTACTTTTCGATGTTAATGATGCTAACATTCTTGGTGATAACTTTTTGAGATCAGCTTATATTGTTT
ATGATTTGGATGATAATGAAATTTCTTTGGCTCAAGTCAAATATACTTCTGCTTCCAGCATTTCTGCCTT
GACCTAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sap2 mutant is attenuated in mice and guinea pigs (Hube et al., 1997).
References
Hube et al., 1997: Hube B, Sanglard D, Odds FC, Hess D, Monod M, Schäfer W, Brown AJ, Gow NA. Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence. Infection and immunity. 1997; 65(9); 3529-3538. [PubMed: 9284116].