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RHO1

Victor ID 4671
Gene Name RHO1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3642557
NCBI Protein GI 68480453
Locus Tag CaO19.10362
Genbank Accession AACQ01000079
Protein Accession XP_715825
Taxonomy ID 237561
Chromosome No R
Gene Starting Position 77159
Gene Ending Position 77755
Gene Strand (Orientation) +
Protein pI 5.4
Protein Weight 19618.63
Protein Length 198
DNA Sequence 
>gi|68480497:77159-77755 Candida albicans SC5314 chromosome R Ctg19-20161, whole genome shotgun sequence
AATGGTTAACGGTCCAGCTGAACTTCGTAGAAAATTAGTCATTGTCGGTGATGGTGCTTGTGGTAAGACT
TGTTTATTAATTGTTTTTTCAAAAGGTACTTTCCCAGAAGTTTATGTCCCAACAGTTTTTGAAAATTACG
TTGCTGATGTTGAAGTTGATGGTAGAAAAGTTGAATTGGCATTATGGGATACTGCTGGTCAAGAAGATTA
TGATAGATTAAGACCATTATCTTATCCAGATTCTAATGTTATTTTGATTTGTTTTTCAGTTGATTCACCA
GATTCTTTAGATAACGTTTTAGAAAAATGGATTTCTGAAGTTTTACATTTCTGTCAAGGTGTTCCAATCA
TTTTAGTTGGTTGTAAATCTGATTTAAGAGATGATCCTCATACTATTGAAGCCTTGAGACAACAACAACA
ACAACCAGTCTCAACTTCTGAAGGCCAACAAGTTGCTCAAAGAATTGGTGCTGCTGATTACTTGGAATGT
TCTGCTAAAACCGGTAGAGGTGTTAGAGAAGTGTTTGAAGCTGCTACTAGAGCTTCTTTAAGAGTTAAAG
AAAAGAAGGAAAAGAAGAAGAAATGTGTTGTCTTGTA
Protein Sequence 
>gi|68480453|ref|XP_715825.1| Ras family GTP-binding protein Rho1p [Candida albicans SC5314]
MVNGPAELRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGRKVELALWDTAGQEDY
DRLRPLSYPDSNVILICFSVDSPDSLDNVLEKWISEVLHFCQGVPIILVGCKSDLRDDPHTIEALRQQQQ
QPVSTSEGQQVAQRIGAADYLECSAKTGRGVREVFEAATRASLRVKEKKEKKKKCVVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: RHO1 mutant is unable to colonize murine kidneys and cause disease in mice (Smith et al., 2002).
References
Smith et al., 2002: Smith SE, Csank C, Reyes G, Ghannoum MA, Berlin V. Candida albicans RHO1 is required for cell viability in vitro and in vivo. FEMS yeast research. 2002; 2(2); 103-111. [PubMed: 12702298].