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pmt5

Victor ID 4667
Gene Name pmt5
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3639011
NCBI Protein GI 68473011
Locus Tag CaO19.7549
Genbank Accession AACQ01000032
Protein Accession XP_719311
Taxonomy ID 237561
Chromosome No R
Gene Starting Position 3666
Gene Ending Position 5843
Gene Strand (Orientation) -
Protein pI 7.86
Protein Weight 80634.26
Protein Length 725
DNA Sequence 
>gi|68473266:3666-5843 Candida albicans SC5314 chromosome R Ctg19-2518, whole genome shotgun sequence
TTTAACCTGTATATGTCATACAATCAATGTCCCAATTTGGAAACCATTTATGAGAATTACATTGATCTAA
TGTCCATGGCAATCCATATGTGATTGGTATAAATTCATAAAAGCAGTATATTGCACTGACAAATATTGTT
GCAGTTATTATACCACCAATAATTTTGTTTTTAGCGACACGATAATTCAAATATTGACTTAATAATAATA
TTCCAAAATTTAATGCCAGTAAATAATGATGTAAATATAAGTTTCTTGACATGAGACAATAAGGAATATA
ATTAATAAACCATCCCACCAAATATGGCCAGGAATTGTTGTAAAAGTTGGCATATGGTGATGATTTGGAT
GATGATGGAGGAGATGCATAAGGGTTTAACTTTATAAACGAATAAATGGCACATTTGAATATAGCTATTA
AACCCACAAAAAATACCAGATAATAAATGGCAACATTTCCTAAATAATAAATTAGACTTGATTCTTCATC
GATTGATTTCAAATTGTAGTTGCTGAAAAAGGCAATACCTCTAGATAAAAGTGGCCAATCAAGTGGTTTA
GAAGCATATGGATGAGGATTAGTGAACCCCTTATTTAAATTAAACATGACTTTATGGGTTTCGATCAATT
TTGACCAAAATGAAAATTTAGGGAAAGTTTTCAATTTTTTGGTATCTTTGAGTAATGGATGTGATGACAG
TTCGACATACCATAATGTATTGGGGATTGTAGGTTCTTTTACACACAATACTTCATTTTGATATTCACCC
CAATCTGGTAGTTTCTGTTCGTGACTCATAAGATTACAACGAGTCGCTTGGTGGATTAATTGGAAAATAG
TCTCTGTGGTTCTTAATTTAATCAAGGGCAAATCATTTTCCGCATGAGGTTTCTTTACCAACATTCGGAT
TTTAAACTCATAATCTTCATTACCCAATAATCCTCTAGTTTCATTCCCATTTACTTCATAACTATATTCA
TGTTCAGAAATAGGTGGACGAATATCATTGACATGTAAATAATGTCCAGTAGCTTTATGGTACAATCTAA
CAACATCACCATCTTTTACTTCTCTTTGATCAGTCATCAATTTTTCTTCATTATATTTCTGTTTTGTTTC
AATTACCCATTCATTGTTGACATCAGGGAAGTCATATAGTGTCACTTGTTGTAAATTCGATCCTCTGGGA
TATGTCAAATCGTGTGAATGCAAATATTTCTCTAATGCATTATGTTTTATAGTGATAGTACTTCCATATA
AAACTTGTAATGGTTGTTGTTGATAATCATCCAAAGTTGATCTGAAGTGTGGTGTTAAAAATCCCGATCC
AGGTCCTTCGTTTGGAAGGTTTTCAAAATGAATATAAAATACTGAACAATATATGGTCAATGGGACCATA
ATAAATGCAACCACACGTAAAACCAAATGCTTGATGAATTGCCAAATAGAAATTCTCAAATCACCCAAAA
TTTCCCATAATTGTACACATGTCAATATTCCAACCCATGCAAATGTAAACAATCCTGAAATTTTCAACGA
GATGTTTAACCCCAAGGCTATCCCAGTAACGAATAAATTGAAGTACCAGCATCCAGTAAATGGAATACGA
GTAGTGAATGCCTTATAATTGTAAATCACCAAACTTTGGACAAATAATGACGGACCTTCTAACAAGATCA
ATCTCGATACTGTCACCATTGAATTTTCCAAACAAATCAAAATAGTAATAACAATCGAAATAACCAGGTT
ACAAGTTATTCTTAATGTGAAAAAAGTCAATAAAACATGTCCAATGCCACAAATACCACTGAATAATCTT
AGCCATAAATATGGGAAATCTTCAGGATACAAATCCCCAATAATATCAATTTGGAAATCTTTATCAAACA
GAAATAATTTCGTGATATAAAAATAAATTAGTTTCCCTAAAGGTGGATGAATATCAACAAATATACTACC
ATCATAATAATTTTTTATATATTTAATTAAATGAATTTCATCAAATACTACTCTATCAGGGATGTATAAT
TTGTATAATCGAATTAATGAAATAAGTAATATGGAAAACACTGCAAATTGTTCGAATTTGGATAATGGTC
GTTCGGTAAGACTTGGTTGGAAAGTTTTGTATGGTCGAAAGGGACCTTGAAAATACCCAGATGGCAATTC
CTTTGTCA
Protein Sequence 
>gi|68473011|ref|XP_719311.1| hypothetical protein CaO19.7549 [Candida albicans SC5314]
MTKELPSGYFQGPFRPYKTFQPSLTERPLSKFEQFAVFSILLISLIRLYKLYIPDRVVFDEIHLIKYIKN
YYDGSIFVDIHPPLGKLIYFYITKLFSFDKDFQIDIIGDLYPEDFPYLWLRLFSGICGIGHVLLTFFTLR
ITCNSVISIVITILICLENSMVTVSRLILLEGPSLFVQSLVIYNYKAFTTRIPFTGCWYFNLFVTGIALG
LNISLKISGLFTFAWVGILTCVQLWEILGDLRISIWQFIKHLVLRVVAFIMVPLTIYCSVFYIHFENLPN
EGPGSGFLTPHFRSTLDDYQQQPLQVLYGSTITIKHNALEKYLHSHDLTYPRGSNLQQVTLYDFPDVNNE
WVIETKQKYNEEKLMTDQREVKDGDVVRLYHKATGHYLHVNDIRPPISEHEYSYEVNGNETRGLLGNEDY
EFKIRMLVKKPHAENDLPLIKLRTTETIFQLIHQATRCNLMSHEQKLPDWGEYQNEVLCVKEPTIPNTLW
YVESSSHPLLKDTKKLKTFPKFSFWSKLIETHKVMFNLNKGFTNPHPYASKPLDWPLLSRGIAFFSNYNL
KSIDEESSLIYYLGNVAIYYSVFFVGLIAIFKCAIYSFIKLNPYASPPSSSKSSPYANFYNNSWPYLVGW
FINYIPYCLMSRNLYLHHYLSALNFGILLLSQYLNYRVAKNKIIGGIITATIFVSAIYCFYEFIPITYGL
PWTLDQCNSHKWFPNWDIDCMTYTG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pmt5 mutant was less virulent in engineered human oral mucosa (EHOM) and in a mouse model of hematogenously disseminated candidiasis (HDC) (Rouabhia et al., 2005).
References
Rouabhia et al., 2005: Rouabhia M, Schaller M, Corbucci C, Vecchiarelli A, Prill SK, Giasson L, Ernst JF. Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases. Infection and immunity. 2005; 73(8); 4571-4580. [PubMed: 16040968].