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PMT2

Victor ID 4665
Gene Name PMT2
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3638538
NCBI Protein GI 68472223
Locus Tag CaO19.6812
Genbank Accession AACQ01000028
Protein Accession XP_719907
Taxonomy ID 237561
Chromosome No 3
Gene Starting Position 188020
Gene Ending Position 190329
Gene Strand (Orientation) -
Protein pI 7.22
Protein Weight 83112.76
Protein Length 769
DNA Sequence 
>gi|68472260:188020-190329 Candida albicans SC5314 chromosome 3 Ctg19-10254, whole genome shotgun sequence
TCTAGGTGTATTGATCATCAGAAACTCTCCAAGATTCCAATAATTTCAAATGTTTCCAATCTTCTTTTGG
TCCTTCCATACCCCAAGACAAATATCTGAAATACCAGAAAGTACCAGCCACTAAAGAGAGTAAACCAATA
TAAATGGCCAAATATAATAATTTCAGCACTGGAGAAGCATTAGGTTTATTTAATCTTGAAGAAAATGATT
CAACTTCATAACAGAAAACAAGCATGGCAAAATAAAGTGCAGGAACATAATGATGAACATATGTAACTCT
TCCCATAATGGCAAATGGTAAGAAATGTAATCCCCATCCAAACATTGGATAAATACCTCCCATAAGGAAT
AATTTCAATTTGTGTGGATTTGTACTTGGGAAATCAACGTATTGTCTTTGCCATCTAATCAAATAATACA
AAACAATGAAAGCAAATAATATAACACCAACAGTAGAAGTCCAAGTAGTTGCTGGTGAACCAATCATATA
ATATTTAGGATTTTCTGGTCCCCATCCACACATTCTAATACCAACATTCAATGTTGGCCATTGCCAAAAT
GATGAAGCCAAATCATCTTGCTTTTCAGTGTCTGGAACTAAAGCATTGTTAGTAGCCATCATGGCCAAAT
TCAATTGAATGAAATCACGAATAAACTTAGTTTTAGGTAATTTGAAATCTTCTGGAGCTGGTGGTAAAAC
TGCATTACGATTGTTTTCAATATTCCACCAAGTTCTCTTGTCTTTTTTAAATGGGTTCTTGTAACAAACA
ACTTCACCTTGTCTGAACCCCCATTGAGGTAATGTAGTACCAGTGACCCCCAAATAACAATTCATCACTT
CATTCTTCAATCTAAATGACGAAGTCAAAGGATGTAATCTCATTTTATCTTCATCACTTGCTTGTTCCAT
AATTTCAACAGTCCAATTATCTTTAGGATCACCAATAGTCAAATTACCATAACATGCAACTTCATATTCA
GATTTAGACACTGGAGCTGGAATATCATGAGTATGTAAGTTTCTACCAGTTTGTGGATGCATCAATCTTA
CATGCATACCGTCAAAAATATATTCAATGTCAGTGGTGTTACCAGAAGTATCATAATAAGGTTGTCCTCT
AGCTCTTTGGAAAATCCAATTGTTGTTTGAATCTTTGTGACCATAAGTAGTAACTTGTTGTTGTTTTGAA
CCTTCTGGGAATGTTTGAACGTGGGAGTGTAAAAGGCCACCACTTAAACCTTGATTCTTTAAAGTGATAA
CCGAGTGGAACATGGATACTTCACGTGGGCCACCACCAACATCGGAACCAGCCAAATTAGCTTGGAAAAG
TGATGACATATTGGCATCACCAGTACCCGATTTATACAACAAATCAAAATGAACTTTAAATGAAAGCATG
AAAATGAAAATTGGGACAAGAATCAAAGCAACAATTCTAGCAAACCAATGTTGAATGTATTTTGTCCATG
AAATAGATTTATCACTCAATTTATTCCAAAGGTCAACAACAGTGTAAATCCCGACCAATGTGGTAACAAA
CAATCCAACCATTTTTACAGAACAAGTACAACCAATGGAAACACCAGTTAAAAGAATCCATTTCCACCAT
TTTCTAGAAAATTCTTGTGATTTATTGTTAAAATTGTTGAAACGTGAAAAACAGAAAACAGTAGCAACGG
TGAAGAATAACAACATTGAATCCAACAAAATGAATTTACCTAAAGTGACATAACTTGATTCAAGAGCCAC
CATCAAAGTAAATAACCAAGTAGTAAACATGGAAAATCCAACTTCTTTCCCAGTGAAATAAGCCAATGGT
ACACACAAGGCAGAGAAAGTGGCATTAAACAATCTCATTTTAGTATAATCAATATAATCAGGGTATTTTT
CACCACTTGGGAAATCCCAAGATCCATTGTATCCAGCCAAATAACCAGATAAACCAACTAACATTTTACC
CAATGGAGGATGAACATCATGATAAAATTCGTGTCGTAAATAATAGGATCCAAATTTACCAAAATGAGCT
TCATCCCAAACAACATGGTCATTCACTGAAATACGATAAAATCTCACGAAAAATGACAATGCAGTGAAAA
CAATAGGTGCTAATATCGATTCAACTTGTTTTAAAGATTCAGCGGTTTCTTTAGCTTCATCATATTGGGT
TCTTTTAAGAGTGTCGTCATCGTCTTCTGCAGCCTCTCCTTGTTGGTGAGGATATTTTTCTTCAATTGAG
GCAGTTGTGGAAAGATCATTCTGCTTTCTCAACAAAGCTTCTGTTTCATTGGGTTCAACAGAAGTAGACA
Protein Sequence 
>gi|68472223|ref|XP_719907.1| hypothetical protein CaO19.6812 [Candida albicans SC5314]
MSTSVEPNETEALLRKQNDLSTTASIEEKYPHQQGEAAEDDDDTLKRTQYDEAKETAESLKQVESILAPI
VFTALSFFVRFYRISVNDHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSG
EKYPDYIDYTKMRLFNATFSALCVPLAYFTGKEVGFSMFTTWLFTLMVALESSYVTLGKFILLDSMLLFF
TVATVFCFSRFNNFNNKSQEFSRKWWKWILLTGVSIGCTCSVKMVGLFVTTLVGIYTVVDLWNKLSDKSI
SWTKYIQHWFARIVALILVPIFIFMLSFKVHFDLLYKSGTGDANMSSLFQANLAGSDVGGGPREVSMFHS
VITLKNQGLSGGLLHSHVQTFPEGSKQQQVTTYGHKDSNNNWIFQRARGQPYYDTSGNTTDIEYIFDGMH
VRLMHPQTGRNLHTHDIPAPVSKSEYEVACYGNLTIGDPKDNWTVEIMEQASDEDKMRLHPLTSSFRLKN
EVMNCYLGVTGTTLPQWGFRQGEVVCYKNPFKKDKRTWWNIENNRNAVLPPAPEDFKLPKTKFIRDFIQL
NLAMMATNNALVPDTEKQDDLASSFWQWPTLNVGIRMCGWGPENPKYYMIGSPATTWTSTVGVILFAFIV
LYYLIRWQRQYVDFPSTNPHKLKLFLMGGIYPMFGWGLHFLPFAIMGRVTYVHHYVPALYFAMLVFCYEV
ESFSSRLNKPNASPVSKLLYLAIYIGLLSLVAGTFWYFRYLSWGMEGPKEDWKHLKLLESWRVSDDQYT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pmt2 mutant has attenuated virulence in a mouse model of hematogenously disseminated candidiasis (HDC) (Rouabhia et al., 2005).
References
Rouabhia et al., 2005: Rouabhia M, Schaller M, Corbucci C, Vecchiarelli A, Prill SK, Giasson L, Ernst JF. Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases. Infection and immunity. 2005; 73(8); 4571-4580. [PubMed: 16040968].