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SPO14

Victor ID 4661
Gene Name SPO14
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3645329
NCBI Protein GI 68486156
Locus Tag CaO19.1161
Genbank Accession AACQ01000137
Protein Accession XP_713028
Taxonomy ID 237561
Chromosome No 1
Gene Starting Position 41704
Gene Ending Position 46836
Gene Strand (Orientation) -
Protein pI 6.63
Protein Weight 187486.7
Protein Length 1710
DNA Sequence 
>gi|68486177:41704-46836 Candida albicans SC5314 chromosome 1 Ctg19-10097, whole genome shotgun sequence
CTCAATCGTAAATTTCCATAGGTGGAAGTCTATCGGTGTTGTAGAACCAATTATTGTTTCGCAATTCAAC
GCTTAACCATTCCGCTGGAAAGTACACCAAGTGTCCCTGCACCGCATTCAATAATCTCTCAGCTGAATTC
TTATCATATACAACATCACCGGTTTGAATTTTTCTTCTAGCTAAATAAGTACGTGCCCTTTTCCTGGTTT
TGGATGCTGGTACTGTTCCAGCAGTAGCAGAAGGTTTATCAGTAGGTGTTCCCGATTCCTCTGATTCTTC
TTCTTCTGTACTTGTCTTTTCCCCACCTTGAAGTTCACCCTCGGATTTAGGCGCTGCTTTGTCACTAAAA
TGTTTATCCCGGTTTTCTGTCACACCAGCAAATGTGCTAACACGACGACTAAGTTTAGCCCTCAAGTTGG
TCTCTTGTTCCAGTTTATTTTGATTCTCAAGACCTCTCTCTGGTGGTGCCTTACCTAACAAACCATACTC
GTCTTCACTCGCTTCGTCAATTTTTTCTAGTTTGGAATTGTTTGCACGTCGTGGTTCTTGGTTATCACCA
GCTTCGACTTTTTCATCGGAGTAGTTTTCTGCCAGTTGACCTTGGTCGGTGTCTGTATCCTGGGCTTTCA
TAAACATACTCTGTAATTTTGTAAAGTGTGTGTACTCTGACCATCTACCCACCACATCATCAGGTTGACA
ATGGAACACCATACGGTATATATCAGTGTTTCTTCTTGCAAATTCATTCCATCGTGCTTCATAGAAATCA
GGATCAATTGGATCTTCAAATTCATATGGATCAACAAAATTACTTACAGCAGCATCAGGGGTTGTCAAAT
TGTTGATGATATCTCTAGCAGCGGGTTCACTCAAAGATACAGTAGGGAACTCTTTATCCAAACTGAAATC
CGTGTCAATTCCCTCGGAAATAGGTAATGTGGCACTGACAGGCAATTCTTGTGATTCGTTACCATTAACA
GCATTTCCAGTTTTAGACAAGAGCGGTAATCCCAATTTTGCCCTTTTTTGGTTCTCTGTATCATTCATGC
TCTTTTCTCTGGCGGCAAGTCTTTGTAAATAAGAGATTTTCTTGAGCAACATCCATCTTTCCTTATTTCT
TTCTGCAATGATATCTTCGGATTCGTCATCCATTTCTCCACTCATATGACAATCATCTGACTCCAAAAAG
TTCCTAACACTATCGAAATCAGGCAAAAACGACCCTGTAGGATTAGTTTCCATGGCAAGGAGGGAAAGCT
CATTCAAAAATTTACCACTGCTAACCCTTGCTCTCTTGGCTAACTTCGACCTGTATTTATCCAACCCTTC
ACCGTAAACATCCTTTTTATGTGACTCGCTATTTTGAACTCTGTTATCGTATGAATGCTTCTTGCTGTCA
CGGACACCTTTATTGGCTTCAAATGGCCCTGTTCGGTTGTTGAATGAAATTGGTAAGAAAAGAGGTGGAG
GTAACGATGTGTCCTCTTCCTCAAAGTTAACCTCGGCAATTTCAGCATCATATTTTGACACATGGATAAA
CTCCTTCCATCTTCTGGTTCCCTCTGGTTGTTGCAAGATATCTCTCGATGCAATCTCTACCATAGCAGAC
AATGTACGGTTCTCGGGGTTTCTAAACTTGTTGGTGGCGAATTTTTTACCTTCCTCTGAAGCAGCAAAAT
TTTGAAATCTCTTAAACCTTCTTTCAGCCACATCAACAATATCAATGTTAACTCCAAGATGCTCTCTCAT
CAACCTCATTCTCAATGTGTGAGCAAACTTAGCTGCCATATATGGCTTACCATTCATTTTACTCTTTACC
ATTTCCTTGTCACGAACAACTGCAGCAACTTCGGAATCACGCAAACCACGCATAGACCTCTCGTTGATGT
TGGCACTCCCAATGATAACCGATCTGTCATCGACAATCATCGTCTTTGCATGAATATACAACTGCTCGGT
AACTAAAGTTCTGTTTGATCCTATTCTACCCCATTTCCGCAAGGAGAAAAATTGAATGTATTGGTCTGGA
TCAATTCCCTTTTTCCTCAATTTTGCAAAAATAGACGTTTCACCTCTGGAAATTGACATATATTGACATT
GCATGATCACACGAACAGAAGACCCTTCTGCTTCATCAACTTGAGCTTCAAAACCAGGCATCAAAGGTAT
GACAATAATAGCCTTCCAATTAGTACCTTCTCTATGTGCTCGAATGATTCTGTCGACCAACGCATCACCA
ATTCTATTCTTAATTTCTGTACCGTCGATGAAACAAGCTGTTACGAAAAATTGATTCTCAATATAGACAA
AATGCTCGGAAGTTTCTATTAATTTGAGATACGCATTTTGAATACTTTGCTCGTGTTCTTTCAAACCAAG
TGACCAATTTCCGGATGATCTCAACAACTGCACCTCACATGTACCATCCAATCCATGAGCTAATACCTCT
TCTTCAGTCAAATCAGATGGAGGCAACAAAAGTGGAGTGAGTCTACTTGGCCGCTTTTGTCTGATTAAAT
AGTTCCATCTCTGAACAAAATGTCTGGACAAATCTCTTGCGGTCTGCCCACATGTATACATATGGACATC
ATGCCAAGGCATACGAGGGACAATATTTCTGTTGTACATGGATTCATATGGCTTTTCGAGTTCCAGGAAA
TCTTTAACTCTAGGATTGGAATAGTCTTTACCCACGAAAACTTGGAAATTCGCAAAGTTTTCTGCTGTGA
TTCTATCGTCCTGTGCGATATTGGAAAAATCAACACCTGAATCGTCTGTTAATGCGTGATCTGGCGTGTC
GTATCTTCCATAACATAAATCTATACCACCCAAGAAAGCGTATGTGTGGTCGATTATACACAATTTTTCG
TGATGAGCCCAAAAGAATGTATTTTGAAGAAGCTGATTTGGTGACCTAATAACATGAATATTCTCTTCAT
CAAGAGACAATATGGAATGTTTTGTGTATAATGAGTCAGTTGCAACCGTTGTACCAACGTTTCTATAAAT
AATCACAAAAATCTTAACACCTTCCTTAGCTTTTCTTTGCAACAATCTATCAATTCTGTATTGTTGGTTA
CCATTTGCTGGTCTTCGAAGATATAATTCCGGAGAAAGCCACCAATCGTGTATCATAATGGTATCCTTGG
CCATTTCCAAAGCAGTGGAGACAGCCCAAAAGTAGTCTCTAGCGTCAACAAACCACTGAGCAAAACAATT
TTCTCTAACTGGGGCAAAGGAATCAAATCTCTTATTTTGGGACCATATTGTCAGATTTTGCATAGTTCTA
AGAGAGTCAATCCAAAGAGAATGCTCTCTTTGAGATTTTGGCAGCATCACTAATTTTCTTTCTCTATTTT
CCAAAGTGATTTTCAAATGTGGGAAAAACTTGTTTTCATTTTCATGCATTTGTTGCTGGGCAACGGAAGA
GTTGTCAAACAATGAATCATCATCATCTCTGTTTGCAATCTCCAAGTTTCTGGCACTGATCTTGAAATCA
CTATCTACCAAAAATACATCTAACGGTGTAGTCGAGTTAATATCCGAGACATATGTGATGTAACTGTTTC
TCACAAGCATCCACTTTTCAACTCTTCTCTCGTAGATTCCTTTCAAATCGTTTACTTTGAAATGGCCAAC
TCTCCAACCTTGTGCTTTAGCAGTCCCCCCAATATGGACTGGACCCTGCTTACCAGTATAGCCAGATTCA
TAACTCAATAATGACGAGAGCGGTGACAACTCAAAGAAAGTAAACAAAATATTTGCCAGGGTTTTTAACT
CTGTAATTTCAATCAATTCCTTCAAATAACTCTCAACATCTTTCATAAATTGTGCATTCTTTTTCCGTCT
GAGCTCAAGCAACTCTGGATGCTTTTCAAGTGAACCCACTGATGTTATACTTCCCAAACGCAGTCTCACT
CTAGACAAAGCTGATGGTACTGGTGAAAGCGAGTGGTTATCGTTAATATCTGGTACTGACATGCGGTCGT
CTCTTGCACGCAGATCAGATAAGACACTTTTAGTCTTTTTGCTTCTTTTGTTATCCAATTTTCGAATTGG
TGGAATTGGAAGTCTGGGTAATGGTTGAGATTTGTTTCCCACAACTCTACTTACAATTCTTGTTCTCTCG
AGTTTGTAAGCTAAATAAGCCAAGTCAGTGGCGTTTCTCTCAATACTCCATTTCATTCTGTGCTTGTCAA
TTCCGTATTCTAAATCAATTCTAAATCTCCTGTTTCTGCTTGTCTCTTTTGGAGTAACGTCGCTCAACTT
GAACCCAAGCACTGACAACAATAACGGGGCTCTGGTTATACCATGTTCATCTTCTAATAGACACGAGGCC
ATTAAATTGATTGCAGGAGCACCAGTGGACATACCTGCTAGTAACTTTTCTGCCCTTTCGATAGTGGCAT
TTTCAGACTCGTCATTAAGCTCATCAAACTCGGCAGTCATGGTGCTTTGTCGCTTATCTTTAGTCTTTCT
TCTATTGAAACGACGCAATGTCTTTATAAATCTGCCACTCTTAGTGCTGTCTTCTCTAGGGTGCAAGGCA
TCATGTAAATTTGCAAATTCGGGCTCAGTATTTGGCATTTCTTGATTAGTGGACGTTGATCTCCCTAAAA
TTCTTGACTGCATAAAACCACTCAAAGTTGCCGAACGAGAATGTGTAGGTCTTGACGACTCCTTTCTCGG
TGGAGCTTTGTTTATATCTTCATTATCCACAAGTTTAAAGCGGTTGGGAAGTTGTTGTTCGTCTTCTGGA
TACTTGCTTTTTCCAAGCAGTTGTCCCTGGGATCTATCCTCATCATATCGGGACTCCTTATCGTCATTGG
AATAATAAAATGAAAGAGGATTACCAATTACTTGTGATGAGTCGTCACGAGTATTTGGGGAAGGAGACCT
ATGTTCTGGGAGAATTGGTCCACTATGGACAGATCGAAAAATTCTGTCTATATCCAGCAGTTTTCGTAAA
GCATCGTTATCGTCAATGGTTCCATCTTGCTGTACTGCTTTCAAATTGTAACTACCATCCTCCTTGTCAT
TGCCAGAAGAAGCTTTTAGTTTCAGATTATTAACATTTTCATCCAATGGGTTCTCATCTAATGGTGAAAT
GGGTTGTTCGGCTGTTGGCAGCA
Protein Sequence 
>gi|68486156|ref|XP_713028.1| hypothetical protein CaO19.1161 [Candida albicans SC5314]
MSPTAEQPISPLDENPLDENVNNSKLKASSGNDKEDGSYNLKAVQQDGTIDDNDALRKSSDIDRIFRSVH
SGPILPEHRSPSPNTRDDSSQVIGNPLSFYYSNDDKESRYDEDRSQGQSLGKSKYPEDEQQLPNRFKLVD
NEDINKAPPRKESSRPTHSRSATLSGFMQSRILGRSTSTNQEMPNTEPEFANLHDALHPREDSTKSGRFI
KTLRRFNRRKTKDKRQSTMTAEFDELNDESENATIERAEKLLAGMSTGAPAINLMASCLLEDEHGITRAP
LLLSVLGFKLSDVTPKETSRNRRFRIDLEYGIDKHRMKWSIERNATDLAYLAYKLERTRIVSRVVGNKSQ
PLPRLPIPPIRKLDNKRSKKTKSVLSDSRARDDRMSVPDINDNHSLSPVPSALSRVRSRLGSITSVGSLE
KHPELLELRRKKNAQFMKDVESYLKELIEITELKTSANILFTFFELSPLSSLLSYESGYTGKQGPVHIGG
TAKAQGWRVGHFKVNDLKGIYERRVEKWMLVRNSYITYVSDINSTTPLDVFLVDSDFKISARNLEIANRD
DDDSLFDNSSVAQQQMHENENKFFPHLKITLENRERKLVMSPKSQREHSLWIDSLRTMQNSTIWSQNKRF
DSFAPVRENCFAQWFVDARDYFWAVSTALEMAKDTIMIHDWWLSPELYLRRPANGNQQYRIDRLLQRKAK
EGVKIFVIIYRNVGTTVATDSLYTKHSILSLDEENIHVIRSPNQLLQNTFFWAHHEKLCIIDHTYAFLGG
IDLCYGRYDTPDHALTDDSGVDFSNIAQDDRITAENFANFQVFVGKDYSNPRVKDFSELEKPYESMYNRN
IVPRMPWHDVHMYTCGQTARDLSRHFVQRWNYLIRQKRPSRLTPLLLPPSDLTEEEVLAHGLDGTCEVQL
LRSSGNWSLGLKEHEQSIQNAYLKLIETSEHFVYIENQFFVTACFIDGTEIKNRIGDALVDRIIRAHREG
TNWKAIIVIPLMPGFEAQVDEAEGSSVRVIMQCQYMSISRGETSIFAKLRKKGIDPDQYIQFFSLRKWGR
IGSNRTLVTEQLYIHAKTMIVDDRSVIIGSANINERSMRGLRDSEVAAVVRDKEMVKSKMNGKPYMAAKF
AHTLRMRLMREHLGVNIDIVDVAERRFKRFQNFAASEEGKKFATNKFRNPENRTLSAMVEIASRDILQQP
EGTRRWKEFIHVSKYDAEIAEVNFEEEDTSLPPPLFLPISFNNRTGPFEANKGVRDSKKHSYDNRVQNSE
SHKKDVYGEGLDKYRSKLAKRARVSSGKFLNELSLLAMETNPTGSFLPDFDSVRNFLESDDCHMSGEMDD
ESEDIIAERNKERWMLLKKISYLQRLAAREKSMNDTENQKRAKLGLPLLSKTGNAVNGNESQELPVSATL
PISEGIDTDFSLDKEFPTVSLSEPAARDIINNLTTPDAAVSNFVDPYEFEDPIDPDFYEARWNEFARRNT
DIYRMVFHCQPDDVVGRWSEYTHFTKLQSMFMKAQDTDTDQGQSAENYSDEKVEAGDNQEPRRANNSKLE
KIDEASEDEYGLLGKAPPERGLENQNKSEQETNLRAKLSRRVSTFAGVTENRDKHFSDKAAPKSEGELQG
GEKTSTEEEESEESGTPTDKPSATAGTVPASKTRKRARTYLARRKIQTGDVVYDKNSAERLLNAVQGHLV
YFPAEWLSVELRNNNWFYNTDRLPPMEIYD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pld1(SPO14) mutants are unable to survive in internal organs after intravenous challenge, and are not lethal for immunodeficient mice after oral challenge (Dolan et al., 2004).
References
Dolan et al., 2004: Dolan JW, Bell AC, Hube B, Schaller M, Warner TF, Balish E. Candida albicans PLD I activity is required for full virulence. Medical mycology : official publication of the International Society for Human and Animal Mycology. 2004; 42(5); 439-447. [PubMed: 15552646].