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PLB1

Victor ID 4660
Gene Name PLB1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Nucleotide GI 3169706
NCBI Protein GI 3445504
Protein Accession AAC61890.1
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name phospholipase B precursor
Protein Note glycosylation site
DNA Sequence 
>gi|3169706|gb|U59710.1|CAU59710 Candida albicans phospholipase B precursor (PLB1) gene, complete cds
ATGATTTTGCATCATTTGTTAATTTTGCTTATTATAAATTATTGTGTTGCTACATCACCAACTAATGGAT
ATGCTCCTGGTCCGGTTTCTTGCCCAAGCAGTCAATTGATTAGATCTGGATCTCAGGGGATCAATCCAAA
TGAACAATCATATATCAATGCCAGATATCCTATTGCCAAACAAGCATTGTCTAAGTTTTTACACAATGCA
AACTTACAAAACTTTGATGTTGATTCGTTCTTAGCACACTCCAATCCAACTATTGGTCTTGCATTCAGTG
GCGGAGGGTATAGAGCAATGTTGACTGGAGCAGGTGAAATCAGTAGCTTGGACTCAAGAACAAAAACCAA
TACTCCAGTTTTAGCAGGCATTTTACAAGCTTCGAGTTATATTGCTGGGTTATCAGGTGGATCGTGGTTA
GTTGGAAGTCTTGCAAGTAATAATTTGAACTCTGTTGATGACATGTTATCTCAAGGTTTGTGGGAACTCA
CACACTCATTTCTTAGTTACTATGGCATTGAACATCCTATAAAGCAAGTTGAAGAATGGGTTAATGTTGG
TAATCAAGTTGCCAGCAAAAGAAATGCAAATTTTAACGTTTCTTTAACTGACATATATGGAAGACTATTA
AGTTACCCTTTGCTCACAAACACAGAAGACGAAGGTGATGCTTATTTGTGGTCAGATGTAACGAGTGCTT
CAAACTTCCAAAGCCACCAAATGCCGTTTCCAATATTGATCAGTGATGGTAGAGCTCCAGATACTACCAT
TATTAATCTCAACTCCACTGTGATTGAATTAACTCCATACGAATTTGGTTCATGGGATCCTAGTTTAAAT
GAATTTGTTGACACTAGATATTTGGGAACAAAATTAGACAATGGTCGTCCAACTGGTAAGTGTTATAATG
GATTTGACAATGCTGGGTTTTTCATGGGTACTTCTTCTGCTCTTTTCAACGAAGCGGTGTTGTCTATCAC
TGAAGCTAACATACCTAGCTTTTTAAAAGATATAATTGATGATATTTTGGTAGATCCAATTCTCAAGTCC
AACATAGACGTGTCTGCTTACAATCCAAATCCATTTTTCAAAAGTTCTGGCAGCAATACTGCTATTTCTC
AATCAAAAAATCTTTATTTAGTTGACGGTGGAGAAGATGGCCAAAACATTCCAATAAGTCCCTTGTTGCA
TCGTAACGTAAGTGCTATATTTGCCTTTGACAATTCCAATGACGTTTTAAACTGGCCAGATGGGACTTCG
TTGGTGAAAACTTATGAACGTCAATTCTCATCACAGGGTAATGGTATTGCTTTCCCATATGTTCCTGATC
AATACACTTTCCGTAATTTGAACTTGACTAGCAAACCTACATTTTTTGGTTGCGATGCAAAAAACTTGAC
TTCATTGACAAAGGATATTTATGATGTTCCCTTGGTTATATACTTGGCAAATCGTCCATTCACTTACTGG
TCTAATACATCAACTTTCAAATTAACATACGACGATAACGAAAGACAAGGCATGATTTCCAATGGATTTG
AAATTGCCACTAGATCAAGTGGATCCTTGGATGATGAATGGGCAGCATGTGTTGGATGCGCCATCATACG
GAGAGAGCAAGAAAGACAAGGTATTGAACAGACAGAACAATGTAAGAGATGCTTTGAAAACTATTGCTGG
GATGGTACCATCTATAAGGGTGAGCCATTAGGTGAAAACTTTAGTGATGATGGATTAACTAATAGTGCTA
CCGAATATAACCTGAATAATGTAGCTGGGTTTAATGACGGAGGAACTCTGATTTTGAAAAAGGCATAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Plb1 mutant is attenuated in mice (Mukherjee et al., 2001).
References
Mukherjee et al., 2001: Mukherjee PK, Seshan KR, Leidich SD, Chandra J, Cole GT, Ghannoum MA. Reintroduction of the PLB1 gene into Candida albicans restores virulence in vivo. Microbiology (Reading, England). 2001; 147(Pt 9); 2585-2597. [PubMed: 11535799].