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PDE2

Victor ID 4658
Gene Name PDE2
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3636877
NCBI Protein GI 68468825
Locus Tag CaO19.2972
Genbank Accession AACQ01000017
Protein Accession XP_721471
Taxonomy ID 237561
Chromosome No 1
Gene Starting Position 100736
Gene Ending Position 102451
Gene Strand (Orientation) +
Protein pI 6.15
Protein Weight 62639.7
Protein Length 571
DNA Sequence 
>gi|68469012:100736-102451 Candida albicans SC5314 chromosome 1 Ctg19-10163, whole genome shotgun sequence
TATGGCAGAAGTATTATCATTGGTTGACCTCGAGATTCCTCAAGTCACTGATAAGTATTATAAATTTGAC
ACTTTTAAACATTTAATCTGTCACTTGTTCAAGAAAACCAGCACAGAAACTGATTCAAATGTTCCTATAG
TAATAATATTCCCGACCAACAATGATATCCCTTCGAGAAAGACTCGATCTACTACTACCACCACCACCAC
TACTACTACTACTAATACCAGCAAGTTAGACAATTTGCCATTCAGTGATAAATCGTTGTTGATACAATTC
TTCTTCACCCATTTGAACATATTGATGATTCAAGGAGAGAATTCGGATGAGGGAAAGTTATATCAAGAAA
TAAGTTCAGCCAAAGAATTATTGACAAATAGGATATCACGAGTTGGAAATTGGACAGGAACAACTCATTT
TAGATACTGTCGACATGAGAATGATTGTGGACTATTGAATCAACATTCCAAAATTGCAGGAATTATACCC
ACAATGACTTACATTCTCAATTGTAATGCAACAAGATCAGAAATTGCCACTAACCAATTGATATATTTAT
ATCGACTCATGATAGAGGAGATTAATTTTATTGAATTGTTACAAGATGCATCTACGACAAGATTATCTCA
GTTGTGTTATGCTGTGGGACATTGGAGTTTCCCTGCTCATAATTTATCAAATGACGATTTGGTTTATTGT
GTTTATTTGATGATAGATTACGCTATCAAACAAGTTGAAGGGTTTGACAACATTCCTTTGAATGAATTAT
TGGCATTTATATTTATTGTTAGAGATACCTATAAGAATGGGAATCCGTTCCATAATTTCCGCCACGCTGT
GGATGTTCTACAAGCTTGTTTCCATTTTCTTATTAGATTGGGTAGTTTACCCAAATTCAAGCAATTTGTC
GAGGACCCGAAATTGGATTACACCGAAGTTCATGACAAACATACTGTATTGATTGCCTTACAAAACAATT
CCTCCGAGGAAAAAGCTTCTCTTAATCCAATACAAACATTAGGATTATTGGTTGCAGCATTGGGCCATGA
TGTGGGCCACCCAGGTACGACAAATGATTTCATGATTAAATTCAGTGCACCAACGGCACTACTTTACAAT
GACAGATCTGTTCTTGAATCTTATCATGCATCTTTATTTATCAATAAAGTGTTAAGAATATGTTGGCCAG
ATTTATTAACTTGTACAATTGAGGAAAAATCAGAGTTAACCATTAGAAGTTTGATAATTTCTTCGATATT
GGCCACCGATATGGGTGAACATAATGAATATGTTAATCGGTTGAAATCTTTCAAGACCCATAATGAAATT
TTAAACCATGATAACACTGTTAAATTGATTTCTGCCTTGTTAATCAAATGTGCTGATATTTCTAACGTGA
CGAGACCGTTGAGAGTATCTGCACAATGGGCAATGGTTTTATCAAGAGAATTTGCAGAAGTTGAGTTGCT
CAAATCGGTAATCAAAAAAGATATTGATCTTGACTTTACCAAAGATTTAACTTATGATGATGTTCCACAT
GAATTACGCGAAATACTTGAAATACAACCCGATATACATAAAGGACAGATATTTTTCATCAATTTATTCG
CTGAGAATTTATTTAATAGTGTTAGTGATTTATTACCTCAATTGCAGTATACTTGTGATATTATTATGGA
AAACAAACTATTTTGGTTGGAAAGAGCAAAGAAATA
Protein Sequence 
>gi|68468825|ref|XP_721471.1| hypothetical protein CaO19.2972 [Candida albicans SC5314]
MAEVLSLVDLEIPQVTDKYYKFDTFKHLICHLFKKTSTETDSNVPIVIIFPTNNDIPSRKTRSTTTTTTT
TTTTNTSKLDNLPFSDKSLLIQFFFTHLNILMIQGENSDEGKLYQEISSAKELLTNRISRVGNWTGTTHF
RYCRHENDCGLLNQHSKIAGIIPTMTYILNCNATRSEIATNQLIYLYRLMIEEINFIELLQDASTTRLSQ
LCYAVGHWSFPAHNLSNDDLVYCVYLMIDYAIKQVEGFDNIPLNELLAFIFIVRDTYKNGNPFHNFRHAV
DVLQACFHFLIRLGSLPKFKQFVEDPKLDYTEVHDKHTVLIALQNNSSEEKASLNPIQTLGLLVAALGHD
VGHPGTTNDFMIKFSAPTALLYNDRSVLESYHASLFINKVLRICWPDLLTCTIEEKSELTIRSLIISSIL
ATDMGEHNEYVNRLKSFKTHNEILNHDNTVKLISALLIKCADISNVTRPLRVSAQWAMVLSREFAEVELL
KSVIKKDIDLDFTKDLTYDDVPHELREILEIQPDIHKGQIFFINLFAENLFNSVSDLLPQLQYTCDIIME
NKLFWLERAKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pde2 mutant is attenuated in mice (Wilson et al., 2007).
References
Wilson et al., 2007: Wilson D, Tutulan-Cunita A, Jung W, Hauser NC, Hernandez R, Williamson T, Piekarska K, Rupp S, Young T, Stateva L. Deletion of the high-affinity cAMP phosphodiesterase encoded by PDE2 affects stress responses and virulence in Candida albicans. Molecular microbiology. 2007; 65(4); 841-856. [PubMed: 17614954].