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NOT4

Victor ID 4656
Gene Name NOT4
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Nucleotide GI 28373259
NCBI Protein GI 28373260
Protein Accession AAF66693.2
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name NOT4p
Protein Note similar to NOT4 (MOT2, SIG1) gene of Saccharomyces cerevisiae
DNA Sequence 
>gi|28373259|gb|AF144710.2| Candida albicans NOT4p (NOT4) gene, complete cds
GAACGAGGCATGTGTGGCTGTAATCAATGCAGGAGTAGTACCTGGCGTAAAAACAGATTCCCATAATTCA
ACAAAAAATGACATGTTCCTAGAAGTAAGAAGTCAAGTTTATGGAATGCTTGGATTGTTAAAGATTTCTA
TAGTAAAAAGATGGATGATTATAATGCTTTTTTTTTCACTACTGGTTACCTAATGTTGAACCACACACGA
CTACATGTTGAGAATTTTTTTTTCCTGCGATTCTTGTATATATTGAAATCGTTTTTTAATTTTTAGATAT
TTGGTGTTTTCAGAAGGCAAATCTATCAATTATAACTAATTACATTTATACAGCTACACAAATTTAACTA
ATCATGATTCAAGCCGACGATACTTTCATCAGTGATGATGAAGAAGAATACTGGTATGTTTAACATAATA
AAGCACAGTTAATTCATTGTGAGTTATTGGTTCAAGTGTATACTAACATATATAATTATCTATAGCCCAT
TATGTGTTGAGGAAATGGATATATCCGACAAAAATTTCAAACCTTGCCCTTGTGGATATCAAATTTGTCA
ATTCTGTTATAACAACATTAGACAAAATCCGGAATTGAATGGAAGGTGTCCGGGGTGTAGAAGACTTTAC
GACGATGAGAGTGTGGAATATAAGACAGTAAGTGCTGAAGAGTACAAATTGATGCAATTGAAAAAGGAAA
AGCGTGACCGTGAAAAGAAACAGAAAGAAAAGGAAAAGAAAGAAATGGAGATGGTCAATAAGAAGCACTT
GGCAGGTTTGAGAGTAGTTCAAAAAAATCTAGTTTATGTCACTGGATTGAATCCACCTTGTAATCCTGAT
GATTTACATTCAGTTTTAAGATCAGACAAATATTTTGGACAATATGGTAAAATTTCCAAGATTGTCATCA
ATAAGAAAACTCCAACAACGCAAACATCAACTCATCATCACCAGAATCCGGGATTGGTAGTGTATGTGAC
TTTCACCAGAAAAGAGGATGCCTTGAGATGTATTACCGAATTGGATGGATCGTTATGTGATGGCAGAGTT
TTGCGTGCTGCTCATGGTACTACTAAATATTGTTCATCGTATTTAAGAGGCCAACCATGTCCAAATCCAA
ATTGTATGTTCTTACATGAACCTGGAGAAGAAGCCGATTCATATACCCGTAAAGATTTATCAACACAACA
AGGTATCAAGATGGGAATGACAGCAAGAAGCCATACAACCTCTTTTGGTGAAGAATCCAGTAATAATAGC
CAATCTAACCAGGCTGGTTCTGATGATGATCACCACGAAGCCCATAAGGAACATTTACCATCCACGGCTC
ATTGGGCAGCAGCTGGAACTACATCTGGAAGCAATTCGCCTTCTGTCAATAATAACATTCCATTAGCGAA
TTCAGCTGCTTTCCCTACATTAGGTGAGATTGTTCGTGATCAAAAGCAACAACAGAAGAAGGAAACCAAG
CCCCGTTCAAAGACTACGAAATCTAACAACACCTTAGTCCCTGACGAATTAGATGCGGGCGATAACTCAG
TGTTCAAGTTCGTCGAAACAACGACTGAACAATTGCGAGGTTTAGAAGATATAAGAAATGTACGCTTCAA
GGGTTTCGACAACGGGAAAATATTACCTTTATTCTCATTTAAAGGTAATTTCCTGAATGATACTCAGCTT
GAAGAAGAAAAGGTCATAGCACGTCAAGTAATTGAGAAGTTTCTTTTGAGACCATTAAAGAACTACCATC
TAGCATATCAAAACCATCCAATCACCCAACAACAAGCAATATTACAACGTCAACAGCAGCAGCAACAACA
ACAACAGCAACAACAGACACCAGCATTACAGGTTGCTCAATTACAACAAAACAAAAATGACGAGCAACAA
AAGCAAGCTCAACAACAGCTCTTGCTACTTCAATTGCAACACCAACAACAGCTCCAGCAACAACAGCAGC
AGCGACAACTTCAACAGCAACAAAATCAGCCACATCAATTGAATATATTAAAAACTTCTGATAGAGTAAA
CACCTCAACTCCACCTCCACCTGGCTTGTTTGCTGGAAAAGATGTTGCCGCTTCCTCAGATATGTCAAAT
ACTGGAGCACCTTTACCTTCATCTAGTTCGCAATTGTTAACTCAATTGATGAGCGGGAAAAGATAAATTC
ATCCCTTACAAGTTTATATTTGATATATAGTACAATAATATTTAGTGATCTGTATACAAAAAGTTTTCGG
GTG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: not4 mutant is attenuated in mice (Krueger et al., 2004).
References
Krueger et al., 2004: Krueger KE, Ghosh AK, Krom BP, Cihlar RL. Deletion of the NOT4 gene impairs hyphal development and pathogenicity in Candida albicans. Microbiology (Reading, England). 2004; 150(Pt 1); 229-240. [PubMed: 14702416].