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MKC1

Victor ID 4652
Gene Name MKC1
Sequence Strain (Species/Organism) Candida albicans 1001 (ATCC 64385)
NCBI Nucleotide GI 619449
NCBI Protein GI 619450
Protein Accession CAA54129.1
Other Database IDs GOA:P43068
InterPro: IPR000719
InterPro: IPR002290
InterPro: IPR003527
InterPro: IPR008271
InterPro: IPR008351
InterPro: IPR008352
InterPro: IPR011009
UniProtKB/UniProt: P43068
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name MAP kinase Mkc1
DNA Sequence 
>gi|619449|emb|X76708.1| C.albicans 1001 (ATCC 64385) MKC1 gene
AGATCTATTTATAGAAATAAATCATTTATGTAGAGTAGAGTGTTTAGACAAAAAAATGTATTTACTATGA
TGTCACATCAACTTCACCGACAACGGTTTCCTGCGTAATATTGCCCTACCATACCTATAAATAAGATTAA
ATCGAAGATACAAACATTCGTATTAAGCCGGTCCTACAGAAAGCCGTTCAAACGTTCACCAATAATATTC
AAAAGATAAAAAAAATTAAACTAAAACGCAAATCAAAATAAAAAATAATTGAAAAGTTGCTAAAAATAGC
GGAAATAGTGTTGTGCAAACCCAATCTCCTAACTATCGCCATAGCTGTATTCCCTCTCGGGCTGGACACT
ATGTGTGCCACAGGTACCCCCACTGATCTTGTTCATATGAACAGGATATAAAAGCTATTGTTTCTTGAAA
TTCTCTCATCAAATTTAGTTCTGAAATTCTCATAAGCTTCACGAGCATACACAAAATCAGCGACAACAAC
AACAGTTACTTCCGTCGCTCTCCCACCCCACTTCCTATCCATTCTACACTAAAAAAAAACCTGAAACCCA
AAAAAAAAAATTTTTTTTTGCTCACTACTAGTTGTCCTTTTTAAACTTTCTCTTGAACAGCAGTTTTATA
AAGAACCAATTTCCATAATGGATCAACAAGAAGCACCCATATATTATGGCAGATCCGTAAATAAGGTCTA
CAACCAGGAATTTATCATTGATAGTCGATTCAAAATAGTCAAGGAGTTGGGCCATGGTGCCTATGGTATT
GTGTGTTCAGCAAAATACGATAATGGGTCCAAAAAGGTTCCTGATTCAAACAACGGTAATGCCTCATCTT
CAGCTAATGCATCGTTTGTGGCAATCAAAAAGATCACTAATATTTTCAGCAAAAACATCTTATGTAAACG
TGCTTTGCGTGAATTGAAGTTGTTGCAGTTCTTCAGGGGCCATAAAAATATAACATGTTTATATGATTTG
GACATTATCCCCAATCCCATGACAGGCGAGTTTAATGAAATATATTTATACGAAGAATTAATGGAATGTG
ACATGCACCAAATCATTAGATCTGGACAACCATTGTCCGATCAGCACTACCAGTCGTTTATTTATCAGGT
ATTGTGTGGATTGAACTTCATCCATTCGGCTGATGTGTTGCATCGTGATTTGAAACCAGGTAACTTACTT
GTCAATGCCGACTGTGAGCTTAAAATTTGTGACTTTGGTTTAGCAAGAGGGTTTTCTGAGAACCCCGACG
AAAATGCTGGGTTTATGACAGAGTATGTTGCCACCAGATGGTACAGGGCACCAGAAATTATGTTGAGTTT
CACCAACTACACTAAGGCAATCGACATCTGGTCTGTTGGTTGTATATTGGCAGAACTTTTGGGGGGCAAG
CCACTTTTCCGTGGCAAAGATTACGTAGATCAACTTAATCAGATTTTAATGATATTAGGTACCCCACCAG
AATCCACGTTACAAAGAATAGGGTCCCACAGAGCCCAGAACTATGTCAGATCTTTGCCGATTACGAGAAA
AGCTAGCTACGAAGAACTTTTCCCTGACGCCAACCCGTTGGCGTTGGATTTATTGGAAAGAATGTTGACT
TTAGACCCACGTGAGAGAATTACAGTTCGAGATGCATTGAATCATAAGTACTTAGAGCTTTGGCATGATC
CTAAAGAAGAAATTGAGTGCCAAGTCAAATTTGATTTCAAGTCGTTTGAGACTGTAGATGGGTTGGACGA
AATGAAACAGTTGATCATGGATGAAGTTCAGAAGTTTCGTGAATTTGTGAGGAAGCCAATTGAGGAACAG
CAGCGAATACAAATGCAGCTACATATGCAAAAACGTGAAGAACAGCGACAAGAGGAGGAAGAGAAAGAGC
TACTAGAACAGCAAAGACAGTTTCCAGCTCAAGAGAGTATGGATATTTCTCAGACCCCTTACAATAACTT
GGAAACGAATATAGGTACTCCTCAGGTTGAAGATGATTATCCCAGACCACAAGAGTTGGATGAGTTTACT
TTTTCAAATTTGGAATCTTCAAGCTCCATGAATTTGTTCCAAGACATGGCTAAACCATCAGGAGAAGAGT
ATATAAAGCTAGAGGAAGAGCTTGGGTTTGGATTAGATTGGTGCTATGTTTAACAACTACTGTAACGACC
ACCAGTAGTTGAAACACACAACCACGTTATCCCGGG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: MKC1 mutant is attenuated in mice (Diez-Orejas et al., 1997).
References
Diez-Orejas et al., 1997: Diez-Orejas R, Molero G, Navarro-García F, Pla J, Nombela C, Sanchez-Pérez M. Reduced virulence of Candida albicans MKC1 mutants: a role for mitogen-activated protein kinase in pathogenesis. Infection and immunity. 1997; 65(2); 833-837. [PubMed: 9009353].