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SUR1

Victor ID 4651
Gene Name SUR1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3644089
NCBI Protein GI 68483590
Locus Tag CaO19.4077
Genbank Accession AACQ01000110
Protein Accession XP_714248
Taxonomy ID 237561
Chromosome No 2
Gene Starting Position 27330
Gene Ending Position 28964
Gene Strand (Orientation) +
Protein pI 7.85
Protein Weight 59578.09
Protein Length 544
DNA Sequence 
>gi|68483679:27330-28964 Candida albicans SC5314 chromosome 2 Ctg19-10196, whole genome shotgun sequence
TATGAGAAAAGAATTGAAATGCATTATTTGGGCCCATGTTGGTCTAATTGTTTATCTATTATATTTATCA
TTTGATTTACTTTCATTATTAAATGATGATATTTTCAGTGATGCATTATTAGACGTTGAAATTAATCCTA
ACCCTAGCACTTCATTAAATAAACCAGCCATTATTCCTAAGATTATCCATCAAACTTATAAAACTACTGA
TATTCCAGAAATTTGGAAACCAGGTCAACAAGCTTGTATCAATCTTCATCAAGACGATTATCAATATTTC
TTATGGACTGATGAACTGGCTCGTGAATTCATCAATAAGGAATTCAACTGGTTTATTGATACTTGGGATA
ATTATAAATATCCTATTCAACGAGCAGACGCTATACGTTATTTTGCCTTGTATTATTACGGTGGGATCTA
TATTGATTTAGATGACGGTTGTAAACGTAAATTAGATCCATTACTCACGGTACCAGCTTTTGTTCGTAAA
ACTGCCCCCACAGGGATCTCCAATGATGTTATGGGTAGTGTTCCTAATCATCCTTTCTTTTTGAAAGTAA
TTCAAGATTTAGAAAAATATCAACGTAATTGGTTGGTGCCGTACATCACCATTATGATGTCAACAGGTCC
ATTATTTTTATCGATCATGTGGAAACAATATAAACGTTGGGGTGTTCCTGAAGCTGGGAAAGTGCGGATT
TTATTACCCCAAAACTATAAAGGAACTACATCTTCATATTTTGCCATAGTTAGAGGCTCATCTTGGCATA
TGGGTGATGCTAATTTTATTAAAAGTTTGGGTGATCATTTGGTATTGGCAGTAATTGGTGGATTTTTACT
TGGTTTATTGATTTTATTTGTGGAATATTTGTTTTATTCTTGGGTGATTTCAAGTCAATGCAAAAGATTA
ACGAGTAAACTTCTTAGTTTTACTTGGGCCATATTAATGGGGGTTTTAAGATTTTTCCATTTAGATAAAC
TTCTATCTAAGTGTGATTTTTGGAGTCGTTCGACAAAGTATGAAGAAATGCTTTTACCAAAAGATAGCAA
TGATTTGAAAAATATCAACAACAATAACACCAGCAATAACAACACTAATGGTGGTGACAGTAACAATAAT
GACAAGAGTGACTATAATAACAACGATAATAACAACAATAACATTAACAACCACACTGGTAAAACTAGAT
TATCATCAATTTTCAATATTTTGGGTGGTAAAACAAAGGTTAAAAGAAGAAATCGTAAAGATTCAAACTT
GCCTATTGAAATTGACGTTTTGAGTAAACTTCTAGATGATACCGTGATAATAGACGCATCAACTACTGAA
ACCCCAACTAACCCTGTTTCTCCAACTCCATCACCAATTTCTCCAACCATTAATTCAAGGACTTCTAATA
ATGAACTTTTAATTCCAACCAATAATAATAATAATAATAATAATAATACTAATGATAATACTAATAATGT
TAATAATATTAATAATAGAACCACTTGCGATGATCAATCAACTTTACTTCCTTATTCGACTCGGTTGTCA
TCATCTTCCTCGTCGTCATCATCATCTCCTTCATCTTCTACTTCTTCATTGCCTAGTCATGAAACTATAA
TGAAATTAAATAATGATATTGTTTA
Protein Sequence 
>gi|68483590|ref|XP_714248.1| hypothetical protein CaO19.4077 [Candida albicans SC5314]
MRKELKCIIWAHVGLIVYLLYLSFDLLSLLNDDIFSDALLDVEINPNPSTSLNKPAIIPKIIHQTYKTTD
IPEIWKPGQQACINLHQDDYQYFLWTDESAREFINKEFNWFIDTWDNYKYPIQRADAIRYFALYYYGGIY
IDLDDGCKRKLDPLLTVPAFVRKTAPTGISNDVMGSVPNHPFFLKVIQDLEKYQRNWLVPYITIMMSTGP
LFLSIMWKQYKRWGVPEAGKVRILLPQNYKGTTSSYFAIVRGSSWHMGDANFIKSLGDHLVLAVIGGFLL
GLLILFVEYLFYSWVISSQCKRLTSKLLSFTWAILMGVLRFFHLDKLLSKCDFWSRSTKYEEMLLPKDSN
DLKNINNNNTSNNNTNGGDSNNNDKSDYNNNDNNNNNINNHTGKTRLSSIFNILGGKTKVKRRNRKDSNL
PIEIDVLSKLLDDTVIIDASTTETPTNPVSPTPSPISPTINSRTSNNELLIPTNNNNNNNNNTNDNTNNV
NNINNRTTCDDQSTLLPYSTRLSSSSSSSSSSPSSSTSSLPSHETIMKLNNDIV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mit1(SUR1) mutant was less virulent during both the acute and chronic phases of systemic infection in mice (Mille et al., 2004).
References
Mille et al., 2004: Mille C, Janbon G, Delplace F, Ibata-Ombetta S, Gaillardin C, Strecker G, Jouault T, Trinel PA, Poulain D. Inactivation of CaMIT1 inhibits Candida albicans phospholipomannan beta-mannosylation, reduces virulence, and alters cell wall protein beta-mannosylation. The Journal of biological chemistry. 2004; 279(46); 47952-47960. [PubMed: 15347680].