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ker1

Victor ID 4643
Gene Name ker1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3638466
NCBI Protein GI 68472127
Locus Tag CaO19.6763
Genbank Accession AACQ01000029
Protein Accession XP_719859
Taxonomy ID 237561
Chromosome No 3
Gene Starting Position 86913
Gene Ending Position 90506
Gene Strand (Orientation) +
Protein pI 4.82
Protein Weight 128368.97
Protein Length 1197
DNA Sequence 
>gi|68472260:86913-90506 Candida albicans SC5314 chromosome 3 Ctg19-10254, whole genome shotgun sequence
TATGTCCGAAACAAAAGAAGCTCCCAAACCAACCAAGCAAGAATCCCAAGGCATATTGAAGAAATTGACC
AGTGGAGATACTTGGGTATCTCCATTTAGATCACAAGCTTCTGAAGAGGACCCTAAAAAGAAAATCAATT
TGTACAAGCAATTCAAAGAATCAAACAAAATTGAACATATTAAAGTTCCTGTTAAGTTTTCTTACCACCC
AACTTTAGAAGCCGAAGCCAAAAAGAAGAAGGCAGCTGAGGCTGAAGCAAAAAAGGCCAAAGAAACCAAA
GCAACAGTTACAAGCACTGAAGCCAAGGATGCCAAAGAAGAAACAGAAACAAAGGCCGAAAAAGTTGAGG
AAAAACTCGAGACTGATGCTAAAGAGCCATTGATTGAAGATGAGACCAAGGAAGAAGCAAAAGTTGATAC
TGAAGCCAAGGAACCATTGATTGAAGACGAAGACAAACAAGAACCGGCCAACGAAGCCGAGGAAAAAGAA
GCTGAACTTGAAGACAAGGCCGAAGAAAAGCTTGTCACAGATCAACCAAAAGACGAAGAAATAGAAGTTG
CTGAACCTAAAGAAGTCTCAGCTGCATCCGAGGTAGAAGAACAAAAACTTGAAAAAGATGCTGCTGAACC
AGAAATTCAAGATGGAGAAGCACTCAAAGGCGATGACAACATTGAAAAACAAATCAAAGAAAACCCAATT
GAACTAGTTGATCAGCCATCTCAGTTCAAGTATGAACCAGTTGAATTGCCAAATAAGGAAACTTTAGATA
AATTGCAAGATAAGCCTGTATTATTGAAACATTATCAAGAATTGAATGCTATTGGCGTTGGATCTATTGC
CAACAGAATCGAGGATCCAAACAAGGTTATTGAATTGGGTTCAGGATTAAGAATGACCCAACAACAATTG
TTGGATATTGCTGCTAAAAGAGTTGCCCCAGTCATTACTAACATCAATGACGAAGTTTCCAAAACAAGAC
AAGAAGATGAAATCAAAAGACAACAGGGGTTGGACAACAAGGTCAAGAAGCATGAAAGTAAATTGCAATC
CGATTTTGAAAAGTATCTTGGTAAAATTGGTAAGAAAAAGGACAAATTCAATAAAGAAATTGAAGAAAAG
TTGGCTAATTTCGAAACTATGATTAAGAAATCAAACAACACTGCCATTGAGTTTGAAAAAACTACCAAAG
GTGAAATTGAAACTGCCAATAAGGAATACGAAGAACGTGAAGCCAAAGCAGTAGAACAACATGCTACTGA
CAAGGAAACTATTGAGAAAAACCACGAAGAATTGTTAGCTACAAAGAAGCAAGAATTGGAAGATGCTAAA
ACTGGTCAAGAAACTGCTACTCAAGAAATTGAGGAATTGAAAGACAAGAAAACTGAATTAGATGACAAAA
ACTCTGAATTGGCTGACAAAATTGAGCAATTGACTGCCCAATTGAATACTGAACTTGCCAAGTTAGATGA
CTTGAAGGCTAACCACAAGGAACACCAAGATTCTATTGATGCCAACTTGACCAAGAAGAAAGAATTAGAT
GATAACTTGACAATCATCCGTAAAGATCTTTCTGATAAAAAGGAGAAGCACAAAGGTTTACTGGCAGAAG
TTGGTGTTTTGGCTGGCTCTGCTGCTGCTTATGCTGCTCGATTAACCAGCTTGCACTCCGACAAAGAGGA
CAGAGCCAAGAGACTTGCTGAAGCCAAGGATAAACACGCTTCTTGGTTGAAAGAGAAGCGGGAATTGGCA
GAACAAACTGCAAGAGATCATGAACGTAAGAGGTTAGAAGCAACTCATGAATACGAGACTCAAAAACACC
TTGAAGAATTAGAAAGACAAAAACAGAAAGAAGAACTCGAAAGAAAAGAAAAAGAAGAGGCCGAAGAAAG
AGAAAGACAAGCCAAGATTGAAGCTGAAGAGCGTGAAAGAAAGGAAAAAGAGGAAGCTGAAGAGAAGGCT
AGACTTGAAAAAGAACAAGCAGAAAAGGAAGCCAAAGAGAAAGAGTTGAAAGAACAACAAGAAAAAGAAG
AAGCTCAGAAGAAAAAAAATGATGTCGAGTACCAAGTCTCGCAAGCAATCTTGTCGAGAGAGACCGACCA
AAAGAAGTTTGAAGAGGAGAGGGCCGAAAGTGAACGTATTTACAATGAACGTAAGGCCAAGGAAAAGGAA
GAAACCGATAGATTGTTGAAAGAAATTGAAGACTTGAAAGCTGAAAAGGAGAAAGCTGCCGAGTTAGAAA
GAGAAGAAGCAGAAAAAGTTGCACAAGCTAAATTGGCACAAATTGAAAAGTTGAAACAAGAACACGAAGC
TAAAACCAAATTGTTCAACGATAAATTGGAATTTGAAAACTTACAAAAACAAAGATTAGAGGAGGAAGTT
GCCAATTTGAAAAAGATTAGGGAATTGAGAGAAGAAAAGGCAAGATTAGCCAGCGAACAATACAAAGACC
CAGAATTGGAAAGAGTCAAGAAATTGATTCAAGAAAGAGAATTGGAGGTGGACAAATTAACCAAAGTGAT
TGAGTTTGAAAAACCAGAACAGACATCATCTGAAGGTGGTCATTTTTTAGGAATTAGCAATGATAGTAAG
TCTGGAGCCATTCCTGTTATTAAATCTAAGGATGTTGTTGTTGGCAACAATGAAAATTCTCATTCAAAGA
GTGTAAACACTGGCAATGAAGCTAAAACAGAAAATGAAAGTGATGATAAGAAGAAAGATCATCATTATGG
AGGAGCAGCTTTAGGAATCGCAGGAGGTATTTTAGCAGCTGCCGGAGCCGGAGCCTTGGCAGCCGGTAGT
GCTGGAAAGAATGCTGTTTCAGGTATTGCTAGTGGTGTTTCAAATGCTGTTCCATCTGGTAATAAAGATG
TGCAATTACCAAGTAATGGTAGTGGCACTCAAGGTAATACTACTACTTCTGCACCAGGTCAAAGTCAATC
TCTGTCTCCCCTTGCAACTACTACTGAACCAAGTGGTTCTGCTGCAAGTATTCCTACTTCAAGCAATACC
AGCACAATTTCTTCTAAAAAAAATGCTGCAAGTGTTACCCCTACTCCAGTTGAAGCGCAACGAACCAATA
GTCTTAGTGACAAATTTAAAGGTTGGGGCAGAAAGTTAAGCAAGAAGGATAAATCCAAAGACGTTAACTC
TGCAGCAGGAGAAACCACTGCGGAAACTGGTGTTATAGCTAAGGATGACGATAAACCAGTTGGTGGAATC
ACAGCTTTGGATGCAGAGAAAAACACTGTTGTTGCTAGAGATGCTAAACCAATTGGAGGAGTCACAGCTT
TAGATGCGGAAAAGAATACTGTCGTTGCCAGAGATACAAAGCCAATTGGCGGTATTAATGCCAATGATAT
TGAAGAAAAACCCAGTGTTGGCATTTTTGTTTCCAAGAATGTTTCTAGTAACAAAACTTCTACTGATGCT
GATGATGAATCTTTTGAAATTCAATCTGTTTACGAAGTTGTCTCAGATAGTGAATATGAAGCTAATAAGC
ACAATCCAAATTATTTTGAAGTTAGTCCAGAAGAGTTTGAGAAACACAAGAATTTGGAAAATAAGGTGGT
CCTTATTGAGAAAATCTCCGAATA
Protein Sequence 
>gi|68472127|ref|XP_719859.1| hypothetical protein CaO19.6763 [Candida albicans SC5314]
MSETKEAPKPTKQESQGILKKLTSGDTWVSPFRSQASEEDPKKKINLYKQFKESNKIEHIKVPVKFSYHP
TLEAEAKKKKAAEAEAKKAKETKATVTSTEAKDAKEETETKAEKVEEKLETDAKEPLIEDETKEEAKVDT
EAKEPLIEDEDKQEPANEAEEKEAELEDKAEEKLVTDQPKDEEIEVAEPKEVSAASEVEEQKLEKDAAEP
EIQDGEALKGDDNIEKQIKENPIELVDQPSQFKYEPVELPNKETLDKLQDKPVLLKHYQELNAIGVGSIA
NRIEDPNKVIELGSGLRMTQQQLLDIAAKRVAPVITNINDEVSKTRQEDEIKRQQGLDNKVKKHESKLQS
DFEKYLGKIGKKKDKFNKEIEEKLANFETMIKKSNNTAIEFEKTTKGEIETANKEYEEREAKAVEQHATD
KETIEKNHEELLATKKQELEDAKTGQETATQEIEELKDKKTELDDKNSELADKIEQLTAQLNTELAKLDD
LKANHKEHQDSIDANLTKKKELDDNLTIIRKDLSDKKEKHKGLSAEVGVLAGSAAAYAARLTSLHSDKED
RAKRLAEAKDKHASWLKEKRELAEQTARDHERKRLEATHEYETQKHLEELERQKQKEELERKEKEEAEER
ERQAKIEAEERERKEKEEAEEKARLEKEQAEKEAKEKELKEQQEKEEAQKKKNDVEYQVSQAILSRETDQ
KKFEEERAESERIYNERKAKEKEETDRLLKEIEDLKAEKEKAAELEREEAEKVAQAKLAQIEKLKQEHEA
KTKLFNDKLEFENLQKQRLEEEVANLKKIRELREEKARLASEQYKDPELERVKKLIQERELEVDKLTKVI
EFEKPEQTSSEGGHFLGISNDSKSGAIPVIKSKDVVVGNNENSHSKSVNTGNEAKTENESDDKKKDHHYG
GAALGIAGGILAAAGAGALAAGSAGKNAVSGIASGVSNAVPSGNKDVQLPSNGSGTQGNTTTSAPGQSQS
SSPLATTTEPSGSAASIPTSSNTSTISSKKNAASVTPTPVEAQRTNSLSDKFKGWGRKLSKKDKSKDVNS
AAGETTAETGVIAKDDDKPVGGITALDAEKNTVVARDAKPIGGVTALDAEKNTVVARDTKPIGGINANDI
EEKPSVGIFVSKNVSSNKTSTDADDESFEIQSVYEVVSDSEYEANKHNPNYFEVSPEEFEKHKNLENKVV
LIEKISE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ker1 mutant had attenuated virulence in systemic mouse infections (Galán et al., 2004).
References
Galán et al., 2004: Galán A, Casanova M, Murgui A, MacCallum DM, Odds FC, Gow NA, Martínez JP. The Candida albicans pH-regulated KER1 gene encodes a lysine/glutamic-acid-rich plasma-membrane protein that is involved in cell aggregation. Microbiology (Reading, England). 2004; 150(Pt 8); 2641-2651. [PubMed: 15289560].