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IRO1

Victor ID 4641
Gene Name IRO1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3636648
NCBI Protein GI 68468453
Locus Tag CaO19.1715
Genbank Accession AACQ01000013
Protein Accession XP_721786
Taxonomy ID 237561
Chromosome No 3
Gene Starting Position 232783
Gene Ending Position 234573
Gene Strand (Orientation) +
Protein pI 4.14
Protein Weight 62087.88
Protein Length 596
DNA Sequence 
>gi|68468490:232783-234573 Candida albicans SC5314 chromosome 3 Ctg19-10123, whole genome shotgun sequence
CATGTTGGATAGATTAAATCGGAAACAATCAAAAGAAAGATTTGTTAACAAGATTCCAATTTCAACAACC
AAAATAGATAAAAGTTTAGAGCATACCCGCAGAGATGATGAATCAAACAACGCTAAAAGAGGTGTTAATC
CCGATGAAAGTTATTCTTCCGATACTTCATTTACACCAACAGTAGTTTCTGGGACTGAAGATGCAGCCCT
TACCCGAACATCAACCAATCGTCAACGACAAGGTAAATCATCCTTCAAGAGCTTTTTCAGAACCATGAGT
TTAAAGGTCAATTCAAAGACAAGAAATAAGGACAGGAAAACTAAAGAAGAATTAGCAGCAGAAAAAGCGC
TTGCCGAACTTAGAAATCTTCCTCGGAATCCTCTTGATCTTGAATTGAATGAACTTCATGTTGCACTGAA
TTTTAATGAAGTGAGAAAAATTATTGACGATATATTTATTGATGAAAACCATGATGCTGCTTCCAAGGCA
ATTAGAATTAGTACCCAAAACAAAAGTTTCAGTGCCATGGAAAAACCTTATAGTTTGACAAAGATAAAGA
GTTTACAAACTGAGGATGACTATAGTCTACCTATAACCTCGTTTATTATAGAAACTTTAGAAGAAAATTC
AATCCATGCCGATCTTTCACACAATGATAATGCAATTACCAGCACAGACATTTTGATTGAAGAAGAGGAA
GAAATGGAGCAAGAGGAGGAAGAAGAAATGTTGAATTATGATGACCTTGATGTTATTAGTGACAAGATTG
ATGAAGTTGGTGCTGAATCTTCCATAAGTACTAGCAATGACAGGGGGATTATTGCAAATGCCACTGCAAA
TGGACCAATCATAGTCGGGGATAGTACTGAAAGTGTTGATACAAGTAACATAGAAAATAGAAAACTTGTT
GTTGTCAACAGCACACCTGACGACCACGACTACTATGCAACCAATGACATGAATGACAACTTCATTACCC
CTAATCCTTCTAATGAAAGTGTTGAAACTCTTGCTGGTGTTTATAAAGATTTTGAGGTTACTAATGCAAC
TGAGGCAAATACTGAGGCAGGCAAAACTACTGATATCAATGCCGAGACTTCAAATGCTATTGATGCAGTA
GCTGATACTGAAAATAAAGTAACCGCTGAGGATGATGCTACTGATACGGTCAACACTGGTGAAAGTATGA
CCGATACAACAACAAGTACTACTGATAATAAGAATGACAAAGAAGTTGACAAAGAAGTTGAAAATGCCGT
TGACTCAAATGTGACTACCAATGATACCATTCCTGATAAAGCAGCAAATATAGATAACGAATCTTCTAGT
GATAACAGTATTGATGCTACTACAGCAAACACAACTAATACTAATAATTTCAATGATGCTGAGGTAAACA
CAGAAGCCACTAACACTATAGTTGACAATGTCACCAATGATAAGTTTAACAGTGTTGACGTCAGTACAAC
TACCCCTACCGCTACGACTGTTTCTGGTATTCCTACTGCGGATGAAATGACCAATAATGTGAACACCAAT
CGAATTTCTACTGCCACCGTCGATAGTTTTACGGGAAAGACTGGTGAGAACTATGAATCCTTCATTACTA
ATGCTGGTAAAGATTCGAACGACAATAATGCAGATTTGAAAACACCCACGAACAATTCTGCAACCACCAC
AACAAATACACAGTCTGGTGTTTCAAATAAAAAATCCAATTCCAAAACCGGATCTTCAGAACAAAATCCA
TTTCAAAAAAAACTTATGAATTATTTAAACAGTTTGAACTG
Protein Sequence 
>gi|68468453|ref|XP_721786.1| putative transcription factor [Candida albicans SC5314]
MLDRLNRKQSKERFVNKIPISTTKIDKSLEHTRRDDESNNAKRGVNPDESYSSDTSFTPTVVSGTEDAAL
TRTSTNRQRQGKSSFKSFFRTMSLKVNSKTRNKDRKTKEELAAEKALAELRNLPRNPLDLELNELHVASN
FNEVRKIIDDIFIDENHDAASKAIRISTQNKSFSAMEKPYSLTKIKSLQTEDDYSLPITSFIIETLEENS
IHADLSHNDNAITSTDILIEEEEEMEQEEEEEMLNYDDLDVISDKIDEVGAESSISTSNDRGIIANATAN
GPIIVGDSTESVDTSNIENRKLVVVNSTPDDHDYYATNDMNDNFITPNPSNESVETLAGVYKDFEVTNAT
EANTEAGKTTDINAETSNAIDAVADTENKVTAEDDATDTVNTGESMTDTTTSTTDNKNDKEVDKEVENAV
DSNVTTNDTIPDKAANIDNESSSDNSIDATTANTTNTNNFNDAEVNTEATNTIVDNVTNDKFNSVDVSTT
TPTATTVSGIPTADEMTNNVNTNRISTATVDSFTGKTGENYESFITNAGKDSNDNNADLKTPTNNSATTT
TNTQSGVSNKKSNSKTGSSEQNPFQKKLMNYLNSLN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: IRO1 mutant is attenuated in mice (Chibana et al., 2005).
References
Chibana et al., 2005: Chibana H, Uno J, Cho T, Mikami Y. Mutation in IRO1 tightly linked with URA3 gene reduces virulence of Candida albicans. Microbiology and immunology. 2005; 49(10); 937-939. [PubMed: 16237272].