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HWP1

Victor ID 4637
Gene Name HWP1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Nucleotide GI 4028879
NCBI Protein GI 1915979
Protein Accession AAC96368.1
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name hyphal wall protein 1
Protein Note hyphal surface protein
DNA Sequence 
>gi|4028879|gb|U64206.1|CAU64206 Candida albicans hyphal wall protein 1 (HWP1) gene, complete cds
GGATCCAAAAACAAGGAATTCGGAAATTCTGACGATAAATGTCGACTCACAATTCATTGTAAAAAGGGAG
AGTTTTGGTAGGCTCATAATCGCTTATAATGTACCTCTAAAGTAATCTAAAACAAACACAACCTTTCTAA
AACCTATAATAATAACCCTAATGGCTCACAACCGGGATAAGTTAGTTAGCCCAGCTGTTTTTTTTTTGCC
TTATTTTTATGACTACATTTTGTTTCACTTTTTGTTGCGACTTTAATACCGTTTTTGCAACTTCTCTTTG
TATCACCTGTATCCGCCTTTTTTAACATAGCAACTCTTGTAAAGTCCCTTTCTTTTCCCACTATTTTATC
ATTCTTGAAATATGTAATCAGAATAGTTTTTCAAAAACTATAAATAACGGTCAAAATAACCGGCTATTTT
CAATTTCCATTCAACTTGTTTTCTCAACAATATCAAACACAACAGGAATCTCCTATAGTCACTCGCTTTT
AGTTTCGTCAATATGAGATTATCAACTGCTCAACTTATTGCTATCGCTTATTACATGTTATCAATTGGGG
CCACTGTCCCACAGGTAGACGGTCAAGGTGAAACAGAGGAAGCTCTTATTCAAAAGAGATCTTATGATTA
CTATCAAGAACCATGTGATGATTACCCACAACAACAACAACAACAAGAGCCTTGTGATTACCCACAACAA
CAACAGCAGGAAGAACCTTGTGATTACCCACAACAACAACCACAAGAGCCATGTGACTATCCACAACAGC
CACAAGAACCTTGTGACTACCCACAACAACCACAAGAACCTTGTGACTACCCACAACAACCACAAGAACC
TTGCGACAATCCACCTCAACCTGATGTTCCTTGTGACAATCCTCCTCAACCTGATGTTCCTTGTGACAAT
CCTCCTCAACCTGATATTCCTTGTGACAATCCTCCTCAACCTGATATTCCTTGTGACAATCCTCCTCAAC
CTGATCAGCCTGATGACAATCCTCCTATTCCAAACATTCCAACCGATTGGATTCCAAATATTCCAACTGA
TTGGATCCCAGATATTCCAGAAAAGCCAACAACTCCAGCTACTACTCCAAACATTCCTGCTACAACTACT
ACTTCTGAATCATCATCTTCTTCTTCTTCTTCATCATCATCTACTACTCCAAAAACTTCTGCTTCAACTA
CACCTGAATCTTCTGTTCCAGCTACCACTCCAAACACTTCTGTTCCAACAACTTCTTCAGAATCAACTAC
TCCAGCTACTAGCCCAGAAAGTTCTGTTCCAGTTACTTCTGGATCATCTATTTTAGCTACCACTTCAGAA
TCATCATCTGCTCCAGCTACTACTCCAAATACATCTGTTCCAACCACTACTACTGAAACCAAATCATCAA
GTACTCCATTAACTACTACTACTGAACATGATACAACTGTTGTCACTGTTACTTCATGTTCTAACAGTGT
TTGTACCGAAAGTGAAGTTACTACTGGTGTTATTGTCATCACATCTAAAGATACTATTTACACCACTTAC
TGTCCATTGACTGAAACTACTCCAGTTTCTACTGCTCCAGCCACTGAAACACCAACTGGTACAGTATCCA
CTTCTACTGAACAATCAACTACTGTTATTACTGTTACTTCATGTTCTGAAAGCTCTTGTACCGAATCTGA
AGTTACTACTGGTGTTGTTGTTGTTACTTCTGAGGAAACTGTCTACACTACATTCTGTCCATTGACTGAA
AACACTCCAGGTACTGATTCAACTCCAGAAGCTTCCATTCCACCTATGGAAACAATTCCTGCTGGTTCAG
AATCATCCATGCCTGCCGGTGAAACCTCTCCAGCTGTTCCAAAATCAGATGTTCCAGCTACTGAATCAGC
TCCAGTTCCTGAAATGACTCCAGCTGGTTCACAACCATCTATTCCTGCCGGTGAAACCTCTCCAGCTGTT
CCAAAATCAGATGTTCCAGCTACTGAATCTGCTCCTGCTCCTGAAATGACTCCAGCTGGTACTGAAACTA
AACCAGCTGCTCCAAAATCATCAGCTCCTGCCACTGAACCTTCCCCAGTTGCTCCAGGTACTGAATCCGC
ACCAGCTGGTCCAGGTGCTTCTTCTTCTCCAAAATCTTCTGTTTTGGCTAGTGAAACCTCACCAATTGCT
CCAGGTGCTGAAACCGCTCCAGCTGGCTCAAGTGGTGCTATTACTATTCCGGAATCTAGTGCTGTCGTCT
CTACGACTGAAGGTGCTATTCCAACTACATTAGAATCAGTTCCACTCATGCAACCATCTGCCAATTACTC
AAGTGTCGCTCCTATTTCTACATTTGAAGGTGCTGGTAACAACATGAGATTGACTTTCGGTGCTGCTATT
ATTGGTATTGCTGCATTCTTGATCTAATTCTAATAACTGATACTAAGTTTTGTTCTTTTTTTGGGATTTC
TTTTTTTTCTAATTTTGATTGTTTTTCAATTTTGGGTTTTCAATATTATTGACAAGAGTCATTTTATTGA
ATATTTGTTTTGTTTACTACATTAAAGGTGATAGGTACTTTTAGTTTTTAAAAATTGTTTTGTTCAAATT
GTTTATCTTTTTCTTCTTCTTCTACTTGCTTTGTTTTCTGTTTTCGGTTCATAGTTGATAGCTTTTAATA
AATACCCCTTTTTTTTTACAAT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Candida albicans strains lacking Hwp1 were unable to form stable attachments to human buccal epithelial cells and had a reduced capacity to cause systemic candidiasis in mice (Staab et al., 1999).
References
Staab et al., 1999: Staab JF, Bradway SD, Fidel PL, Sundstrom P. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. Science (New York, N.Y.). 1999; 283(5407); 1535-1538. [PubMed: 10066176].