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HOG1

Victor ID 4636
Gene Name HOG1
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3637270
NCBI Protein GI 68469771
Locus Tag CaO19.8514
Genbank Accession AACQ01000018
Protein Accession XP_721137
Taxonomy ID 237561
Chromosome No 2
Gene Starting Position 215620
Gene Ending Position 216753
Gene Strand (Orientation) +
Protein pI 4.82
Protein Weight 40465.84
Protein Length 377
DNA Sequence 
>gi|68469802:215620-216753 Candida albicans SC5314 chromosome 2 Ctg19-20076, whole genome shotgun sequence
AATGTCTGCAGATGGAGAATTTACAAGAACCCAGATATTTGGGACTGTTTTTGAAATCACCAATAGATAC
ACTGAGCTAAATCCCGTGGGAATGGGAGCATTTGGTTTGGTGTGCTCAGCCGTTGATAGATTAACTGGTC
AAAATGTTGCAGTGAAAAAAGTCATGAAACCTTTTCTGACCTCAGTATTGGCAAAAAGAACCTACAGAGA
ATTAAAGTTATTGAAACATTTGAAACATGAGAATTTGATTACCTTGGATGATATTTTCATATCTCCTTTG
GAGGATATTTACTTTGTCAATGAATTGCAAGGTACTGATTTGCATAGGTTATTGAACTCAAGACCTTTGG
AGAAACAATTTATTCAATATTTCACATACCAAATAATGAGAGGTTTAAAATACATTCATTCTGCCGGTGT
TATTCATCGTGATTTGAAACCATCCAACATCTTGATCAATGAAAACTGTGACTTGAAAATCTGTGACTTT
GGTCTTGCAAGACTTCAAGATCCACAAATGACGGGTTACGTGTCAACCAGATATTATCGAGCACCAGAAA
TCATGTTAACTTGGCAAAAATACGACACTGAAGTCGACTTGTGGTCTGTGGGTTGTATCTTAGCGGAAAT
GATTGAAGGGAAACCACTATTCCCCGGGAAAGATCACGTGCATCAATTCTCCATTATAACAGAATTATTG
GGCTCACCTCCTGCTGATGTGATCGATACTATTTGTTCCGAAAACACTTTAAGATTTGTCCAATCATTAC
CACATAGAGACCCTATCCCATTTAGTGAAAGATTTGCTTCCTGTACTCACGTTGAACCGGAGGCTATTGA
TTTATTGGCTAAATTGTTGGTTTTTGACCCTAAGAAAAGAATCAGTGCTGTTGAAGGTTTGACCCATCCT
TATATGGAGGCATACCATGATCCAACCGATGAGCCTGTTTGTGAGAGTAAATTCGATTGGAGTTTTAATG
ACGCAGACTTGCCAGTGGATACTTGGAGAGTTATGATGTACAGTGAAATTTTAGACTTTCATCAAACTGT
TGGTGTGGCAAATGAAACTGAGGGTTCCGAACAACCAGACCTGCAAGTGGAGCAAAACAACTTGGATTCC
GCCAACGGAGCTTA
Protein Sequence 
>gi|68469771|ref|XP_721137.1| likely protein kinase [Candida albicans SC5314]
MSADGEFTRTQIFGTVFEITNRYTELNPVGMGAFGLVCSAVDRLTGQNVAVKKVMKPFSTSVLAKRTYRE
LKLLKHLKHENLITLDDIFISPLEDIYFVNELQGTDLHRLLNSRPLEKQFIQYFTYQIMRGLKYIHSAGV
IHRDLKPSNILINENCDLKICDFGLARLQDPQMTGYVSTRYYRAPEIMLTWQKYDTEVDLWSVGCILAEM
IEGKPLFPGKDHVHQFSIITELLGSPPADVIDTICSENTLRFVQSLPHRDPIPFSERFASCTHVEPEAID
LLAKLLVFDPKKRISAVEGLTHPYMEAYHDPTDEPVCESKFDWSFNDADLPVDTWRVMMYSEILDFHQTV
GVANETEGSEQPDSQVEQNNLDSANGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hog1 mutant is attenuated in mice (Alonso-Monge et al., 1999).
References
Alonso-Monge et al., 1999: Alonso-Monge R, Navarro-García F, Molero G, Diez-Orejas R, Gustin M, Pla J, Sánchez M, Nombela C. Role of the mitogen-activated protein kinase Hog1p in morphogenesis and virulence of Candida albicans. Journal of bacteriology. 1999; 181(10); 3058-3068. [PubMed: 10322006].