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GAT1

Victor ID 4632
Gene Name GAT1
Sequence Strain (Species/Organism) Candida albicans
NCBI Nucleotide GI 31559063
NCBI Protein GI 31559064
Protein Accession AAP50501.1
Taxonomy ID 5476
Gene Strand (Orientation) ?
Protein Name nitrogen regulatory GATA-factor
DNA Sequence 
>gi|31559063|gb|AY293736.1| Candida albicans nitrogen regulatory GATA-factor (GAT1) gene, complete cds
ATGACAATGAATTTTAATCAAACAGGTAAATATCAATCTCCATATGTTAAATCGCCATCATCAACCACGT
CAACCTTCCCACCAGCAACAAAATCAAACAAACAACAACTGCTACCATTGCAGCTTAACTCGTTCACAGC
CACTACACCCTTATCACAAGTGATAAGTAAAGAGCAAGATCATATTGAAAATGTATGGAAAATGTACTAC
CGTGCTCGTCACTCATTGCCTTATCAAAAAAGAATGGAGAACTTGACTTGGAGGATGATGTATATTAACA
ACAAATCGATTTTCACTAATACTAACAATGCACCTAAAGAGGTTTTTGAACAAAGTTTGGATCCTGAAAT
TGATGATTTTGATTATGTGGCACATATAAAAAAGATTGGTCAATTTAATCAGCAAAAAACACAACAACAA
CAAGATCATTTGCAATCAAATTTAGACAATCACAATAGTATATTTGCTGATAACACTGGTTTTTCTAACA
ACAATGACAGAGGTAGTTCAGGTGGTGGTATGACTTCCATAAGTAGTTTACTGAAGAAAAGACCAGCTCC
ATTTTCGCCAATGATTCAACCAGAAAAGACGACAATCATCCCCACTGCCACTAATACAATGTCCCAATTA
TCACAACAATTAAATGAATTCAATAAATTTAACCACCCCAGTCAAACATCCAATTTTAATGACGTTAATC
ATCATATGGAAATTTCAACGTCCCATATAGCCCCTACTTCTTCGGCTTTTGAGTTTTCCTTAGATCCATT
GGCATTTGAAGGTCCAAATCAAAATTTCCAACCTGAACCGCACCATGATTTCAACACCAACTCTTTTGAT
TCTATGACATCATCATATGAGAGACCCTTGTTTGACGATTTTCTTCCTCGTGATCATCATAATATTCAAA
GCTCAAGTGTGCCTACTTCAGCATCGTCATTTTCAACAATTGTGCCGAAAAATACCCAATTCTCAACGTC
AGCATCAATAACATCGCCAACGTCAACATTTTCCAATCAAGGCAATAATAGCAGTAATTTCCACCGATTG
AATTCTACTGTCAGTATAACGGCAACCCCGGGTAATTTATTACGTCAAGAATCAATGGTCAGCTTACCAG
ATTATGCCAACCATTTACGATCAATGTCGCAAACTCCAACTATGAATAGTAGTAATGCACCATTCTCGCA
TAGTTTTAATGATAGTGGTAGCTATTTTATGAATAATTTTACTGGAATCACATTACCTAGTCAACCGTCA
CCACAACCTATTCATTTTGATAATAAACCAAAAGATGATCATTTTAATACTTCGTTATCTGTGTCACAAC
AGCAACCTTCTGCCAAAAAACTGAAACGAAAATCGACCATTACAAAATCGAAAAAGAAAGCTGCAAGTCC
TGAAACCACAATAACCAGTACTGGAAGCACTATTACGACGAAATCAACGAACTCAAATTCAACTGGTAAG
GGAACAGCGACCGGACCAGCAGCACTGAATACTGGTGTTTCTTGTACAAATTGTGGAACAAAAACTACTC
CATTATGGAGACGAAATCCCCAAGGTCAACCATTGTGTAATGCATGTGGTTTATTTTTGAAATTGCATGG
GGTGGTGCGTCCATTGAGTTTGAAAACAGATGTGATCAAGAAACGTCAACGTGGTAACAATAATGGTAGT
GGAAATAGCAGTGGCACAACAAACAATAGTAATAATAACAATAATAAATCAATTAGTAAAAAGAATGAGA
TTGATGATGGTGATGATTTAAACCCTACTTCGATAACTAATAATACGGGTTTGACAAACAATAATAATAG
TAAATCTCCGGCCAAATCAAAAAAGAAATCAAATTTTGACAACAACAGTAACAGTGCTCTTAACAACTTG
GATAAATCTAAATTGAAAATCAATACTAATGAGATCACAAACATTTCTGAGACCACATCGAATAGCTCAT
CACCAGTGATTAACTTGAATCACGGGGGAAGATCTTCTGGAGTGTTTGGTAATACCCCAGATTATTTAAA
TGGAATAACTTCACCCGCAGTGTCCCTTGTTAAATCTGAGATTGATAATCCTCATCAATTAAATAATAGC
AATAGTAATGGAATGTTGATGACGATGCATCAGTCACTGCATCAACTGTCGCTACTGACAACGTTTGATC
ATGAGGTAGAATCAAATAATGAGGGTTCCAATTCTAGTGGAGTCAATACATCAACTGCTAATAATCAAGA
TTGGGATTGGTTAAACATGAATTATTAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gat1 mutants are highly attenuated in a murine model of disseminated candidiasis (Limjindaporn et al., 2003).
References
Limjindaporn et al., 2003: Limjindaporn T, Khalaf RA, Fonzi WA. Nitrogen metabolism and virulence of Candida albicans require the GATA-type transcriptional activator encoded by GAT1. Molecular microbiology. 2003; 50(3); 993-991004. [PubMed: 14617156].