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FKH2

Victor ID 4631
Gene Name FKH2
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3640536
Uniprot ID Q5A7S7
NCBI Protein GI 68476229
Locus Tag CaO19.5389
Genbank Accession AACQ01000050
Protein Accession XP_717764
Taxonomy ID 237561
Chromosome No 3
Gene Starting Position 38238
Gene Ending Position 39818
Gene Strand (Orientation) +
Protein pI 9.86
Protein Weight 57416.49
Protein Length 526
DNA Sequence 
>gi|68476394:38238-39818 Candida albicans SC5314 chromosome 3 Ctg19-10227, whole genome shotgun sequence
AATGTCAGCACAATTTATCACACCGAAAAAGCGTCCCCACTCACCACTAGATAGTAATGAATTACTTCCT
TCTTTTGAAGATCCCCAGGATATGATAAATGCAGTGGTATCTACGTTACTGGCTCCAGAGGAGAAAACCA
ATGTTTCTATTGCATATGCCAATGAGAAAAATCAAGCCACAGAAATCCAAGCCTATGCTAAGATTGCTGG
TAAGGATTGGACATTTTATGTCAAGTCATTGGCAGTTTCGATAGGAAGAAATATTGAATTATCCGCACCC
AGTAATACTAATATAACTACACCTTTAATAGATATTGACTTGGGCCCAGCTAAAGTAGTCAGTAGACTGC
ATGCCGCTATTACTTATAATCTAGATTTAAGATGTTGGGAGTTAAAAGTTCTTGGAAGAAATGGTGCAAG
AATAGACGGTCAAAAAGTTAATGTTGATTCACCAAATGTTAATGCATTACATTCAGGGGCAATTTTGGAT
ATTGGTGGTACCCAAATGATGTTTATTTTGCCTGATGCTCCAGCAGTTGTTGCCCCGAAAATGTTGGAGA
AATGTCTTCTCAGATACAAGGAGCAACAACAACAACAGAACAAACGAATTTCAAGTGGACCTGGTATCGG
TGGCTCCACAAGTTTTCAAATGTTTGATAAAGCTCATCTAACTCATTCCCCTTCATCTATTTCAGCAAAC
TCGCTCCAATCAAATTTGGATCAAGACTTGTCAAAAGAGGAAGCCAAAGATATCAAGCCTCCCTATTCTT
ATGCGACAATGATTACGCAAGCAATCTTATCGAATCCTCAAGGAGTAATGTCATTATCTGAGATTTACAA
TTGGATTGCTGATCATTACGCATACTATAAATACTCGAAAACTGGTTGGCAAAATTCGATTAGACACAAT
TTGTCCTTGAATAAAGCGTTTGAAAAAGTTCCAAGAAGACCAAATGAACCAGGAAAAGGTATGAAATGGC
AAATTAGTGAATCATACAAGGAAGAATTTTTAAACAAAATTTCTGATGGAACCATCCTGAAAACAAGAAG
AGGTTCTTCAGTTTCTAGACAATTGAGTTTACATTTGGCTACTCATAACCAATTACCCGAATCACACAAG
TATACAATGGATCAACAAATACACAACGGTACCGCTGCTTCAATACCTCAGCAACAAAAACAACAACAAC
AACAACAAAAACGACCACCACAACAACAGAATTCACAGCCACACTTGTCGCAACCCCATTACACAATTCC
TTCTAATCCCATGCAAACCAATTCCATGGGATACATACCACAATCCAATATTTACAATATGTCAAATAGC
GATCGTCGTTATACACCATACCAACAACTGCAAAACCCACTTATGTATCAACATCAACAGCAACATATTG
GCCAAACATATAACCAATTAGGGCGACCACAAGGCCAGCTAGGACAACCAATGATGCAACCTCAACAACA
AAGCTACACCCTGAGTAACATTAAAACCGAGCCCAGTTCTCCAAAAAGAAATCCATCTATTTCTAACAAC
ACACCAAAGATGGCTAAAGGCACAGGTATGTATTTTAAATA
Protein Sequence 
>gi|68476229|ref|XP_717764.1| potential forkhead-like transcriptional regulator [Candida albicans SC5314]
MSAQFITPKKRPHSPLDSNELLPSFEDPQDMINAVVSTLSAPEEKTNVSIAYANEKNQATEIQAYAKIAG
KDWTFYVKSLAVSIGRNIELSAPSNTNITTPLIDIDLGPAKVVSRSHAAITYNLDLRCWELKVLGRNGAR
IDGQKVNVDSPNVNALHSGAILDIGGTQMMFILPDAPAVVAPKMLEKCLLRYKEQQQQQNKRISSGPGIG
GSTSFQMFDKAHLTHSPSSISANSLQSNLDQDLSKEEAKDIKPPYSYATMITQAILSNPQGVMSLSEIYN
WIADHYAYYKYSKTGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWQISESYKEEFLNKISDGTISKTRR
GSSVSRQLSLHLATHNQLPESHKYTMDQQIHNGTAASIPQQQKQQQQQQKRPPQQQNSQPHLSQPHYTIP
SNPMQTNSMGYIPQSNIYNMSNSDRRYTPYQQSQNPLMYQHQQQHIGQTYNQLGRPQGQLGQPMMQPQQQ
SYTSSNIKTEPSSPKRNPSISNNTPKMAKGTGMYFK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fkh2 mutant are unable to damage human epithelial or endothelial cells in vitro (Bensen et al., 2002).
Predicted Interacting Host Protein A6NCE0; A6NIR3; A8MT82; A8MTJ6; A8MUV4; A8MYZ6; B0QYV8; B0QYV9; B3KNZ8; B4DIT1; B5B2M6; B5B2M7; B7ZAP5; B7ZBM3; B8ZZY2; B9UN80; C9J0F0; C9J808; C9JN36; C9JTA7;
C9JUY9; C9JVP0; C9JZR4; D6R992; D6RC45; D6RDI9; D6RF93; D6RH30; E5RGL6; E5RHC5; E5RIU2; E7ETU6; E7EU13; E7EUN2; E7EV62; E9PFD3; E9PI38; E9PIY6; E9PJR1; E9PJT7;
E9PJZ9; E9PK28; E9PKH5; E9PKV4; E9PM18; E9PM37; E9PM47; E9PM63; E9PMD5; E9PMR9; E9PMU9; E9PN48; E9PN69; E9PNK5; E9PNV4; E9PNY8; E9PPI7; E9PQP3; E9PQS6; E9PRX2;
F5GXM9; F5H4S8; F6XZ68; F8VVT9; F8VWB3; F8VXI9; F8W7V0; F8W822; F8WAK2; G3V3A7; G5E965; G5E9L0; G5E9Y3; H0Y873; H0Y882; H0YBF7; H0YDX1; H0YE36; H0YG99; H0YJ22;
H0YJ54; H0YJ94; H0YJG3; H3BR83; H3BRS1; H7BY03; H7BZL0; H7C0A7; H7C1Y6; H7C3K3; H7C3T5; I3L3K7; J3KNM6; J3KQL4; J3KRL6; J3KT45; J3KT70; J3QRA6; J3QRD3; J3QRU8;
K7EN79; K7ER53; M0R119; M0R279; O00358; O00409; O15353; O15409; O43150; O43524; O43638; O60548; O75593; O75689; O94916; O95081; O95644; P19838; P32314; P52594;
P55316; P55317; P55318; P58012; P85037; P98177; Q00653; Q01167; Q01201; Q04206; Q04864; Q08050; Q0PRL4; Q12778; Q12946; Q12947; Q12948; Q12950; Q12951; Q12952;
Q12968; Q13461; Q13469; Q14161; Q14934; Q15027; Q15057; Q16676; Q17RU2; Q2TAM5; Q2V6Q1; Q3SYB3; Q5SRD3; Q5T2P9; Q5VTM2; Q5VUJ5; Q5VV16; Q5VW22; Q5VYV0; Q6PIV2;
Q6PJQ5; Q6VB84; Q6VB85; Q6ZQN5; Q8IVH2; Q8IYB5; Q8N6H7; Q8N6T3; Q8TDY4; Q8TF27; Q8WU79; Q8WWN8; Q8WXT5; Q8WZ64; Q92949; Q96NZ1; Q96P47; Q96P48; Q96P50; Q96P64;
Q99490; Q99853; Q99958; Q9BYG3; Q9BZS1; Q9C009; Q9H334; Q9NP61; Q9NPF8; Q9NU39; Q9P0K8; Q9UJU5; Q9ULH1; Q9UPQ3; Q9UPW0; Q9Y261; Q9Y2X7; R4GNB7
References
Bensen et al., 2002: Bensen ES, Filler SG, Berman J. A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans. Eukaryotic cell. 2002; 1(5); 787-798. [PubMed: 12455696].