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UTR2

Victor ID 4623
Gene Name UTR2
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3636747
NCBI Protein GI 68468620
Locus Tag CaO19.9240
Genbank Accession AACQ01000013
Protein Accession XP_721629
Taxonomy ID 237561
Chromosome No 3
Gene Starting Position 148154
Gene Ending Position 149566
Gene Strand (Orientation) +
Protein pI 4.31
Protein Weight 49521.82
Protein Length 470
DNA Sequence 
>gi|68468731:148154-149566 Candida albicans SC5314 chromosome 3 Ctg19-20123, whole genome shotgun sequence
TATGAGATTTTCAACACTTCATTTTGCCTTTTTGGCAACATTATCGAGCATTTTCACTGTCGTGGCTGCT
TCTGACACTACTACTTGTAGTTCAAGTAAACATTGTCCTGAAGATAAACCATGCTGTTCTCAATTTGGTA
TCTGTGGTACTGGGGCTTATTGTTTAGGCGGTTGTGATATTAGATATTCTTATAATTTGACTGCTTGTAT
GCCTATGCCTAGAATGAGTACATTCCAAGAATCATTTGATTCTAAAGATAAAGTTAAAGAAATTGAATTA
CAATCGGATTATTTAGGTAATTCTACTGAAGCTGACTGGGTTTATACTGGTTGGGTTGATTATTATGACA
ATTCTTTATTAATTCAAATGCCAAATCATACCACTGGTACCGTTGTTTCATCGACTAAATACTTATGGTA
CGGTAAAGTTGGGGCAACATTGAAAACATCTCATGATGGTGGGGTTGTTACTGCTTTTATTTTGTTTTCT
GATGTTCAAGATGAAATTGATTATGAATTTGTTGGGTATAATTTAACTAATCCTCAATCAAATTATTATT
CTCAAGGGATTTTAAATTATAATAATTCGAGAAATTCTTCCGTAAATAATACTTTTGAATATTATCATAA
TTATGAAATGGATTGGACTGAAGATAAAATTGAATGGTACATTGATGGAGAAAAAGTCCGTACTTTAAAT
AAAAATGATACTTGGAATGAAACTAGTAATCGTTATGATTACCCTCAAACTCCTTCAAGAATTCAATTTT
CTTTATGGCCCGGTGGTGATTCTTCAAATGCTAAAGGTACTATTGAATGGGCTGGTGGATTAATCAATTG
GGATTCTGAAGATATTAAGAAATATGGATATTATTATGCTCACATTAAAGAGATTTATGCCACTGCCTAT
GATATACCCAATGATGTTAAATTGGATGGTAATTCCACTAAAGAATCAGATTATCATGCTTTCCTTTATA
ATAGTACTGATGGTGATGCTAGTAACATTATGTTGACCACGAAAAAGACTTGGTTAGGTAGCGATGACGC
TACTGGATTTGATCCACAAAATGATGATGAAGATAGTAGTAGTAACAAAGCTCAAGAAACTACCATCACT
TCAGTTAGTGGGTCATCTACTATAACTAGTGTTAAAACTGATTCAACTAAAAAAACTGCTAATGTTCCTG
CTCAAAACACTGCCGCAGCAGCACAAGCAACTGCTAAAAGTTCTACTGGTACCAACACCTATGATCCAAG
TGCTGGAGTTGGTGGATTTGTTCAAGATTCAAAATCTACTGATTCTGGTAGTAGTGGAAGCAGTTCTCAA
GGTGTTGCCAATTCATTAAATGAAAGTGTTATCAGTGGTATATTTGCTTCCATTTGCTTGGGTATATTAT
CATTTTTCATGTA
Protein Sequence 
>gi|68468620|ref|XP_721629.1| hypothetical protein CaO19.9240 [Candida albicans SC5314]
MRFSTLHFAFLATLSSIFTVVAASDTTTCSSSKHCPEDKPCCSQFGICGTGAYCLGGCDIRYSYNLTACM
PMPRMSTFQESFDSKDKVKEIELQSDYLGNSTEADWVYTGWVDYYDNSLLIQMPNHTTGTVVSSTKYLWY
GKVGATLKTSHDGGVVTAFILFSDVQDEIDYEFVGYNLTNPQSNYYSQGILNYNNSRNSSVNNTFEYYHN
YEMDWTEDKIEWYIDGEKVRTLNKNDTWNETSNRYDYPQTPSRIQFSLWPGGDSSNAKGTIEWAGGLINW
DSEDIKKYGYYYAHIKEIYATAYDIPNDVKLDGNSTKESDYHAFLYNSTDGDASNIMLTTKKTWLGSDDA
TGFDPQNDDEDSSSNKAQETTITSVSGSSTITSVKTDSTKKTANVPAQNTAAAAQATAKSSTGTNTYDPS
AGVGGFVQDSKSTDSGSSGSSSQGVANSLNESVISGIFASICLGILSFFM
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: csf4 (UTR2) mutant has reduction in adherence to mammalian cells and attenuated virulence in an immunocompetent mouse model of disseminated candidiasis (Alberti-Segui et al., 2004).
References
Alberti-Segui et al., 2004: Alberti-Segui C, Morales AJ, Xing H, Kessler MM, Willins DA, Weinstock KG, Cottarel G, Fechtel K, Rogers B. Identification of potential cell-surface proteins in Candida albicans and investigation of the role of a putative cell-surface glycosidase in adhesion and virulence. Yeast (Chichester, England). 2004; 21(4); 285-302. [PubMed: 15042589].